Anapc7 | ENSMUSG00000029466 | NCBI 56317

Details for: Anapc7

Gene ID: 56317

Symbol: Anapc7

Ensembl ID: ENSMUSG00000029466

Description: anaphase promoting complex subunit 7

Associated with

Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-MMU-176814)
Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Apc-cdc20 mediated degradation of nek2a
(R-MMU-179409)
Apc/c-mediated degradation of cell cycle proteins
(R-MMU-174143)
Apc/c:cdc20 mediated degradation of cyclin b
(R-MMU-174048)
Apc/c:cdc20 mediated degradation of mitotic proteins
(R-MMU-176409)
Apc/c:cdc20 mediated degradation of securin
(R-MMU-174154)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-MMU-174178)
Apc:cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
(R-MMU-179419)
Assembly of the pre-replicative complex
(R-MMU-68867)
Autodegradation of cdh1 by cdh1:apc/c
(R-MMU-174084)
Cdc20:phospho-apc/c mediated degradation of cyclin a
(R-MMU-174184)
Cdk-mediated phosphorylation and removal of cdc6
(R-MMU-69017)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Conversion from apc/c:cdc20 to apc/c:cdh1 in late anaphase
(R-MMU-176407)
Dna replication
(R-MMU-69306)
Dna replication pre-initiation
(R-MMU-69002)
Immune system
(R-MMU-168256)
Inactivation of apc/c via direct inhibition of the apc/c complex
(R-MMU-141430)
Inhibition of the proteolytic activity of apc/c required for the onset of anaphase by mitotic spindle checkpoint components
(R-MMU-141405)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Phosphorylation of the apc/c
(R-MMU-176412)
Regulation of apc/c activators between g1/s and early anaphase
(R-MMU-176408)
Regulation of mitotic cell cycle
(R-MMU-453276)
Senescence-associated secretory phenotype (sasp)
(R-MMU-2559582)
Separation of sister chromatids
(R-MMU-2467813)
S phase
(R-MMU-69242)
Switching of origins to a post-replicative state
(R-MMU-69052)
Synthesis of dna
(R-MMU-69239)
Anaphase-promoting complex
(GO:0005680)
Brain development
(GO:0007420)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Enzyme-substrate adaptor activity
(GO:0140767)
Heterochromatin
(GO:0000792)
Microtubule cytoskeleton
(GO:0015630)
Nucleus
(GO:0005634)
Positive regulation of mitotic metaphase/anaphase transition
(GO:0045842)
Protein k11-linked ubiquitination
(GO:0070979)
Protein phosphatase binding
(GO:0019903)
Protein ubiquitination
(GO:0016567)
Spindle
(GO:0005819)

Other Information

Proteins

Anaphase-promoting complex subunit 7

Genular Protein ID: 1201891311

Symbol: APC7_MOUSE

Name: Anaphase-promoting complex subunit 7

UniProtKB Accession Codes:

Q9WVM3 Q3UBM7 Q8BSR2 Q91W13

Database IDs:

Citations:

PubMed ID: 10515598

Title: A new autoantigen reactive with prediabetic nonobese diabetic mice sera.

PubMed ID: 10515598

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 34942119

Title: APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain.

PubMed ID: 34942119

DOI: 10.1016/j.molcel.2021.11.031

Sequence Information:

Length: 565
Mass: 63021
Checksum: F7DFB8D45FDCD639
Sequence:

MSVIDHVRDM AAAGLHSNVR LLSSLLLTMS NNNPELFSPS QKYQLLVYHA DSLFHDKEYR 
NAVSKYAMAL QQKKALSKTS KVRPSTGNSA STPQSQCLPS EIEVKYKMAE CYTMLKLDKD 
AIAVLDGIPS RQRTPKINMM LANLYKKAGQ ERPSVTSYKE VLRQCPLALD AILGLLSLSV 
KGAEVASMTM NVIQTVPNLD WLSVWIKAYA FVHTGDNSRA INTICSLEKK SLLRDNVDLL 
GSLADLYFRA GDSKNSVLKF EQAQMLDPYL IRGMDVYGYL LAREGRLEDV ENLGCRLFNI 
SDQHAEPWVV SGCHSFYSKR YSRALYLGAK AIQLNSNSVQ ALLLKGAALR NMGRVQEAII 
HFREAIRLAP CRLDCYEGLI ECYLASNSIR EAMVMANNVY KTLGANAQTL TLLATVCLED 
PVTQEKAKTL LDKALAQRPD YVKAVVKKAE LLSREQKYED GIALLRNALA NQSDCVLHRI 
LGDFLVAVNE YQEAMDQYSI ALSLDPNDQK SLEGMQKMEK EESPTDATQE EDVDDMEGSG 
EEGDLEGSDS EAAQWADQEQ WFGMQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Anapc7

Associated with

Other Information

A new autoantigen reactive with prediabetic nonobese diabetic mice sera. PubMed ID: 10515598

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337