Details for: Mettl3
Associated with
Other Information
Genular Protein ID: 882448582
Symbol: MTA70_MOUSE
Name: N6-adenosine-methyltransferase subunit METTL3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9409616
Title: Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.
PubMed ID: 9409616
PubMed ID: 11389549
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
PubMed ID: 11389549
DOI: 10.1002/mrd.1017
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 24209618
Title: RNA-methylation-dependent RNA processing controls the speed of the circadian clock.
PubMed ID: 24209618
PubMed ID: 25456834
Title: m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.
PubMed ID: 25456834
PubMed ID: 24394384
Title: N-methyladenosine modification destabilizes developmental regulators in embryonic stem cells.
PubMed ID: 24394384
DOI: 10.1038/ncb2902
PubMed ID: 25683224
Title: m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
PubMed ID: 25683224
PubMed ID: 25569111
Title: Stem cells. m6A mRNA methylation facilitates resolution of naive pluripotency toward differentiation.
PubMed ID: 25569111
PubMed ID: 28809392
Title: Mettl3-mediated m(6)A regulates spermatogonial differentiation and meiosis initiation.
PubMed ID: 28809392
DOI: 10.1038/cr.2017.100
PubMed ID: 28965759
Title: Temporal control of mammalian cortical neurogenesis by m(6)A methylation.
PubMed ID: 28965759
PubMed ID: 28914256
Title: Mettl3-/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis.
PubMed ID: 28914256
DOI: 10.1038/cr.2017.117
PubMed ID: 28637692
Title: m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
PubMed ID: 28637692
PubMed ID: 28792938
Title: m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.
PubMed ID: 28792938
DOI: 10.1038/nature23450
PubMed ID: 28869969
Title: m(6)A modulates haematopoietic stem and progenitor cell specification.
PubMed ID: 28869969
DOI: 10.1038/nature23883
PubMed ID: 29535189
Title: Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
PubMed ID: 29535189
PubMed ID: 29547716
Title: Zc3h13 regulates nuclear RNA m6A methylation and mouse embryonic stem cell self-renewal.
PubMed ID: 29547716
PubMed ID: 32943573
Title: Context-dependent functional compensation between Ythdf m6A reader proteins.
PubMed ID: 32943573
Sequence Information:
- Length: 580
- Mass: 64616
- Checksum: 0DBDA2392A37A018
- Sequence:
MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSSG PKPSTTSVAP ELATDPELEK KLLHHLSDLA LTLPTDAVSI RLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAMMGAV ADKKGLGEVA GTIAGQKRRA EQDLTTVTTF ASSLASGLAS SASEPAKEPA KKSRKHAASD VDLEIESLLN QQSTKEQQSK KVSQEILELL NTTTAKEQSI VEKFRSRGRA QVQEFCDYGT KEECMKASDA DRPCRKLHFR RIINKHTDES LGDCSFLNTC FHMDTCKYVH YEIDACVDSE SPGSKEHMPS QELALTQSVG GDSSADRLFP PQWICCDIRY LDVSILGKFA VVMADPPWDI HMELPYGTLT DDEMRRLNIP VLQDDGFLFL WVTGRAMELG RECLNLWGYE RVDEIIWVKT NQLQRIIRTG RTGHWLNHGK EHCLVGVKGN PQGFNQGLDC DVIVAEVRST SHKPDEIYGM IERLSPGTRK IELFGRPHNV QPNWITLGNQ LDGIHLLDPD VVARFKQRYP DGIISKPKNL
Genular Protein ID: 1226343927
Symbol: A0A0R4J041_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 580
- Mass: 64630
- Checksum: B86E7869DF058ED0
- Sequence:
MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSSG PKPSTTSVAP ELATDPELEK KLLHHLSDLA LTLPTDAVSI RLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAMMGAV AEKKGLGEVA GTIAGQKRRA EQDLTTVTTF ASSLASGLAS SASEPAKEPA KKSRKHAASD VDLEIESLLN QQSTKEQQSK KVSQEILELL NTTTAKEQSI VEKFRSRGRA QVQEFCDYGT KEECMKASDA DRPCRKLHFR RIINKHTDES LGDCSFLNTC FHMDTCKYVH YEIDACVDSE SPGSKEHMPS QELALTQSVG GDSSADRLFP PQWICCDIRY LDVSILGKFA VVMADPPWDI HMELPYGTLT DDEMRRLNIP VLQDDGFLFL WVTGRAMELG RECLNLWGYE RVDEIIWVKT NQLQRIIRTG RTGHWLNHGK EHCLVGVKGN PQGFNQGLDC DVIVAEVRST SHKPDEIYGM IERLSPGTRK IELFGRPHNV QPNWITLGNQ LDGIHLLDPD VVARFKQRYP DGIISKPKNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.