Txnip | ENSMUSG00000038393 | NCBI 56338

Details for: Txnip

Gene ID: 56338

Symbol: Txnip

Ensembl ID: ENSMUSG00000038393

Description: thioredoxin interacting protein

Associated with

Immune system
(R-MMU-168256)
Inflammasomes
(R-MMU-622312)
Innate immune system
(R-MMU-168249)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-MMU-168643)
The nlrp3 inflammasome
(R-MMU-844456)
Cell cycle
(GO:0007049)
Cellular response to tumor cell
(GO:0071228)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enzyme inhibitor activity
(GO:0004857)
Keratinocyte differentiation
(GO:0030216)
Negative regulation of cell division
(GO:0051782)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Platelet-derived growth factor receptor signaling pathway
(GO:0048008)
Positive regulation of apoptotic process
(GO:0043065)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Protein transport
(GO:0015031)
Regulation of cell population proliferation
(GO:0042127)
Response to oxidative stress
(GO:0006979)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Thioredoxin-interacting protein

Genular Protein ID: 4282733730

Symbol: TXNIP_MOUSE

Name: Thioredoxin-interacting protein

UniProtKB Accession Codes:

Q8BG60 Q8BGQ0 Q8K2B2 Q9DC00 Q9EP90 Q9R115

Database IDs:

Citations:

PubMed ID: 10843682

Title: Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function.

PubMed ID: 10843682

DOI: 10.4049/jimmunol.164.12.6287

PubMed ID: 11376942

Title: Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene.

PubMed ID: 11376942

DOI: 10.1016/s0378-1119(01)00455-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15930262

Title: Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1.

PubMed ID: 15930262

DOI: 10.1158/0008-5472.can-04-2271

PubMed ID: 15723808

Title: VDUP1 is required for the development of natural killer cells.

PubMed ID: 15723808

DOI: 10.1016/j.immuni.2004.12.012

Sequence Information:

Length: 397
Mass: 44363
Checksum: C160781B207C99A6
Sequence:

MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS 
QQCKQTLDYL RYEDTLLLEE QPTAGENEMV IMRPGNKYEY KFGFELPQGP LGTSFKGKYG 
CVDYWVKAFL DRPSQPTQEA KKNFEVMDLV DVNTPDLMAP VSAKKEKKVS CMFIPDGRVS 
VSARIDRKGF CEGDDISIHA DFENTCSRIV VPKAAIVARH TYLANGQTKV FTQKLSSVRG 
NHIISGTCAS WRGKSLRVQK IRPSILGCNI LKVEYSLLIY VSVPGSKKVI LDLPLVIGSR 
SGLSSRTSSM ASRTSSEMSW IDLNIPDTPE APPCYMDIIP EDHRLESPTT PLLDDVDDSQ 
DSPIFMYAPE FQFMPPPTYT EVDPCVLNNN NNNNNVQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Txnip

Associated with

Other Information

Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. PubMed ID: 10843682

Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene. PubMed ID: 11376942

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. PubMed ID: 15930262