Details for: Eif3c

Gene ID: 56347

Symbol: Eif3c

Ensembl ID: ENSMUSG00000030738

Description: eukaryotic translation initiation factor 3, subunit C

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-MMU-72662)
  • Cap-dependent translation initiation
    (R-MMU-72737)
  • Eukaryotic translation initiation
    (R-MMU-72613)
  • Formation of a pool of free 40s subunits
    (R-MMU-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-MMU-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-MMU-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-MMU-156827)
  • Metabolism of proteins
    (R-MMU-392499)
  • Ribosomal scanning and start codon recognition
    (R-MMU-72702)
  • Translation initiation complex formation
    (R-MMU-72649)
  • Cytoplasm
    (GO:0005737)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Eukaryotic translation initiation factor 3 complex, eif3m
    (GO:0071541)
  • Ribosome binding
    (GO:0043022)
  • Rna binding
    (GO:0003723)
  • Translation
    (GO:0006412)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)
  • Translation initiation factor binding
    (GO:0031369)

Other Information

Genular Protein ID: 1072274722

Symbol: EIF3C_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8R1B4 Q8R3M7

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17622165

Title: A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.

PubMed ID: 17622165

DOI: 10.1021/pr070122r

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 911
  • Mass: 105531
  • Checksum: A88282C5B4C55AEB
  • Sequence:
    • MSRFFTTGSD SESESSLSGE ELVTKPVSGN YGKQPLLLSE DEEDTKRVVR SAKDKRFEEL 
TNLIRTIRNA MKIRDVTKCL EEFELLGKAY GKAKSIVDKE GVPRFYIRIL ADLEDYLNEL 
WEDKEGKKKM NKNNAKALST LRQKIRKYNR DFESHITNYK QNPEQSADED AEKNEEDSEG 
SSDEDEDEDG VGNTTFLKKK QESSGESRKF HKKMEDDDED SEDSEDEEWD TSSTSSDSDS 
EEEEGKQTVL ASKFLKKAPT TEEDKKAAEK KREDKAKKKH DRKSKRLDEE EEDNEGGEWE 
RVRGGVPLVK EKPKMFAKGT EITHAVVIKK LNEILQVRGK KGTDRATQIE LLQLLVQIAA 
ENNLGVGVIV KIKFNIIASL YDYNPNLATY MKPEMWQMCL DCINELMDTL VAHSNIFVGE 
NILEESENLH NFDQPLRVRG CILTLVERMD EEFTKIMQNT DPHSQEYVEH LKDEAQVCAI 
IERVQRYLEE KGTTEEICQI YLRRILHTYY KFDYKAHQRQ LTPPEGSSKS EQDQAENEGE 
DSAVLMERLC KYIYAKDRTD RIRTCAILCH IYHHALHSRW YQARDLMLMS HLQDNIQHAD 
PPVQILYNRT MVQLGICAFR QGLTKDAHNA LLDIQSSGRA KELLGQGLLL RSLQERNQEQ 
EKVERRRQVP FHLHINLELL ECVYLVSAML LEIPYMAAHE SDARRRMISK QFHHQLRVGE 
RQPLLGPPES MREHVVAASK AMKMGDWKTC HSFIINEKMN GKVWDLFPEA DKVRTMLVRK 
IQEESLRTYL FTYSSVYDSI SMETLSDMFE LDLPTVHSII SKMIINEELM ASLDQPTQTV 
VMHRTEPTAQ QNLALQLAEK LGSLVENNER VFDHKQGTYG GYFRDQKDGY RKNEGYMRRG 
GYRQQQSQTA Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.