Rybp | ENSMUSG00000072872 | NCBI 56353

Details for: Rybp

Gene ID: 56353

Symbol: Rybp

Ensembl ID: ENSMUSG00000072872

Description: RING1 and YY1 binding protein

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-MMU-8939243)
Transcriptional regulation by e2f6
(R-MMU-8953750)
Transcriptional regulation by runx1
(R-MMU-8878171)
Apoptotic process
(GO:0006915)
Chromatin remodeling
(GO:0006338)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Metal ion binding
(GO:0046872)
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032435)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleic acid binding
(GO:0003676)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pcg protein complex
(GO:0031519)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of dna-templated transcription
(GO:0045893)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Transcription coregulator activity
(GO:0003712)
Transcription corepressor activity
(GO:0003714)

Other Information

Proteins

RING1 and YY1-binding protein

Genular Protein ID: 1635351197

Symbol: RYBP_MOUSE

Name: RING1 and YY1-binding protein

UniProtKB Accession Codes:

Q8CCI5 B2RRB6 Q9WVK2

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10369680

Title: RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1.

PubMed ID: 10369680

DOI: 10.1093/emboj/18.12.3404

PubMed ID: 14765135

Title: Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.

PubMed ID: 14765135

DOI: 10.1038/sj.cdd.4401391

PubMed ID: 16055728

Title: Rybp/DEDAF is required for early postimplantation and for central nervous system development.

PubMed ID: 16055728

DOI: 10.1128/mcb.25.16.7193-7202.2005

PubMed ID: 17070805

Title: The Polycomb-associated protein Rybp is a ubiquitin binding protein.

PubMed ID: 17070805

DOI: 10.1016/j.febslet.2006.10.027

PubMed ID: 17874297

Title: Rybp interacts with Hippi and enhances Hippi-mediated apoptosis.

PubMed ID: 17874297

DOI: 10.1007/s10495-007-0131-3

PubMed ID: 19170609

Title: The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA.

PubMed ID: 19170609

DOI: 10.1021/bi801933c

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22325148

Title: RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.

PubMed ID: 22325148

DOI: 10.1016/j.cell.2011.12.029

PubMed ID: 22226355

Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

PubMed ID: 22226355

DOI: 10.1016/j.stem.2011.12.006

PubMed ID: 27748911

Title: RING1 and YY1 binding protein suppresses breast cancer growth and metastasis.

PubMed ID: 27748911

DOI: 10.3892/ijo.2016.3718

PubMed ID: 28596365

Title: PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.

PubMed ID: 28596365

DOI: 10.1126/science.aal2512

Sequence Information:

Length: 228
Mass: 24777
Checksum: 80E4D647244E213D
Sequence:

MTMGDKKSPT RPKRQAKPAA DEGFWDCSVC TFRNSAEAFK CSICDVRKGT STRKPRINSQ 
LVAQQVAQQY ATPPPPKKEK KEKVEKPDKE KPEKDKDISP SVTKKNTNKK TKPKSDILKD 
PPSEANSIQS ANATTKTSET NHTSRPRLKN VDRSTAQQLA VTVGNVTVII TDFKEKTRSS 
STSSSTVTSS AGSEQQNQSS SGSESTDKGS SRSSTPKGDM SAVNDESF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rybp

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1. PubMed ID: 10369680

Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing. PubMed ID: 14765135

Rybp/DEDAF is required for early postimplantation and for central nervous system development. PubMed ID: 16055728

The Polycomb-associated protein Rybp is a ubiquitin binding protein. PubMed ID: 17070805

Rybp interacts with Hippi and enhances Hippi-mediated apoptosis. PubMed ID: 17874297

The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA. PubMed ID: 19170609

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. PubMed ID: 22325148

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. PubMed ID: 22226355

RING1 and YY1 binding protein suppresses breast cancer growth and metastasis. PubMed ID: 27748911

PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. PubMed ID: 28596365