Akap8 | ENSMUSG00000024045 | NCBI 56399

Details for: Akap8

Gene ID: 56399

Symbol: Akap8

Ensembl ID: ENSMUSG00000024045

Description: A kinase anchor protein 8

Associated with

Cell cycle g2/m phase transition
(GO:0044839)
Cellular response to lipopolysaccharide
(GO:0071222)
Cellular response to prostaglandin e stimulus
(GO:0071380)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Condensed chromosome
(GO:0000793)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Double-stranded dna binding
(GO:0003690)
Female pronucleus
(GO:0001939)
Histone deacetylase binding
(GO:0042826)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Metal ion binding
(GO:0046872)
Mitotic chromosome condensation
(GO:0007076)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Nf-kappab binding
(GO:0051059)
Nuclear matrix
(GO:0016363)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein kinase a regulatory subunit binding
(GO:0034237)
Protein transport
(GO:0015031)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

A-kinase anchor protein 8

Genular Protein ID: 1526847024

Symbol: AKAP8_MOUSE

Name: A-kinase anchor protein 8

UniProtKB Accession Codes:

Q9DBR0 Q9R0L8

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 12414807

Title: AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.

PubMed ID: 12414807

DOI: 10.1074/jbc.m206387200

PubMed ID: 12082153

Title: Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes.

PubMed ID: 12082153

DOI: 10.1242/jcs.115.14.2931

PubMed ID: 14641107

Title: A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95.

PubMed ID: 14641107

DOI: 10.1042/bj20031765

PubMed ID: 16227597

Title: A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.

PubMed ID: 16227597

DOI: 10.1128/mcb.25.21.9469-9477.2005

PubMed ID: 16751186

Title: Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse.

PubMed ID: 16751186

DOI: 10.1074/jbc.m603626200

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19531803

Title: Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105.

PubMed ID: 19531803

DOI: 10.1126/scisignal.2000202

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 687
Mass: 76294
Checksum: BC1E320216A47E10
Sequence:

MEQGYGGYGA WSAGPANTQG TYGSGMTSWQ GYENYNYYNA QNTSVPAGTP YSYGPASWEA 
TKTNDGGLAA GSPAMHVASF APEPCTDNSD SLIAKINQRL DMLSKEGGRG GISSGGEGVQ 
DRDSSFRFQP YESYDARPCI PEHNPYRPGY GYDYDFDLGT DRNGSFGGTF NDCRDPAPER 
GSLDGFLRGR GQGRFQDRSN SSTFIRSDPF MPPSASEPLS TTWNELNYMG GRGLGGPSTS 
RPPPSLFSQS MAPDYSMMGM QGVGGFGGTM PYGCGRSQTR IRDWPRRRGF ERFGPDNMGR 
KRKQFPLYEE PDAKLARADS DGDLSENDDG AGDLRSGDEE FRGEDDLCDS RKQRGEKEDE 
DEDVKKRREK QRRRDRMRDR AADRIQFACS VCKFRSFEDE EIQKHLQSKF HKETLRFIST 
KLPDKTVEFL QEYIINRNKK IEKRRQELLE KESPKPKPDP FKGIGQEHFF KKIEAAHCLA 
CDMLIPAQHQ LLQRHLHSVD HNHNRRLAAE QFKKTSLHVA KSVLNNKHIV KMLEKYLKGE 
DPFVNETADL ETEGDENVGE EKEETPEEVA AEVLAEVITA AVKAVEGEGE PAAAHSDVLT 
EVEGPVDTAE ASSDPHTEKL LEEQTCEAAS ETRSIEDKTR GEAAEARNEA AMPTADAGST 
LPVIAIPGIM EDELEQTGAE AKDIPTE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Akap8

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex. PubMed ID: 12414807

Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes. PubMed ID: 12082153

A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95. PubMed ID: 14641107

A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association. PubMed ID: 16227597

Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse. PubMed ID: 16751186

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105. PubMed ID: 19531803

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315