Diaph3 | ENSMUSG00000022021 | NCBI 56419

Details for: Diaph3

Gene ID: 56419

Symbol: Diaph3

Ensembl ID: ENSMUSG00000022021

Description: diaphanous related formin 3

Associated with

Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rhoa gtpase cycle
(R-MMU-8980692)
Rhob gtpase cycle
(R-MMU-9013026)
Rhoc gtpase cycle
(R-MMU-9013106)
Rhod gtpase cycle
(R-MMU-9013405)
Rhof gtpase cycle
(R-MMU-9035034)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Rhoq gtpase cycle
(R-MMU-9013406)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Actin binding
(GO:0003779)
Actin crosslink formation
(GO:0051764)
Actin cytoskeleton organization
(GO:0030036)
Actin filament
(GO:0005884)
Actin filament bundle
(GO:0032432)
Actin filament bundle assembly
(GO:0051017)
Actin filament organization
(GO:0007015)
Actin filament polymerization
(GO:0030041)
Actin nucleation
(GO:0045010)
Autophagosome-lysosome fusion
(GO:0061909)
Cell projection organization
(GO:0030030)
Cellular component organization
(GO:0016043)
Chromosome segregation
(GO:0007059)
Cleavage furrow
(GO:0032154)
Cytokinesis
(GO:0000910)
Cytoplasm
(GO:0005737)
Cytoskeletal protein binding
(GO:0008092)
Cytoskeleton organization
(GO:0007010)
Endosomal transport
(GO:0016197)
Erythrocyte differentiation
(GO:0030218)
Erythrocyte enucleation
(GO:0043131)
Escrt i complex
(GO:0000813)
Establishment of cell polarity
(GO:0030010)
Filamentous actin
(GO:0031941)
Gene expression
(GO:0010467)
Head development
(GO:0060322)
Inner ear receptor cell differentiation
(GO:0060113)
Integrin-mediated signaling pathway
(GO:0007229)
In utero embryonic development
(GO:0001701)
Macrophage differentiation
(GO:0030225)
Microtubule binding
(GO:0008017)
Microtubule cytoskeleton organization
(GO:0000226)
Microtubule organizing center
(GO:0005815)
Microtubule polymerization
(GO:0046785)
Negative regulation of microtubule depolymerization
(GO:0007026)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Organelle organization
(GO:0006996)
Podosome assembly
(GO:0071800)
Protein-containing complex remodeling
(GO:0034367)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of deacetylase activity
(GO:0150065)
Ribbon synapse
(GO:0097470)
Sensory perception of sound
(GO:0007605)
Small gtpase binding
(GO:0031267)
Spindle checkpoint signaling
(GO:0031577)
Spindle pole
(GO:0000922)
Stereocilia tip-link density
(GO:1990427)

Other Information

Proteins

Protein diaphanous homolog 3

Genular Protein ID: 147785033

Symbol: DIAP3_MOUSE

Name: Protein diaphanous homolog 3

UniProtKB Accession Codes:

Q9Z207

Database IDs:

Citations:

PubMed ID: 9535835

Title: Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7.

PubMed ID: 9535835

DOI: 10.1074/jbc.273.15.8616

PubMed ID: 10678165

Title: Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling.

PubMed ID: 10678165

DOI: 10.1016/s1097-2765(00)80399-8

PubMed ID: 19117945

Title: mDia2 shuttles between the nucleus and the cytoplasm through the importin-{alpha}/{beta}- and CRM1-mediated nuclear transport mechanism.

PubMed ID: 19117945

DOI: 10.1074/jbc.m806191200

PubMed ID: 23558171

Title: Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

PubMed ID: 23558171

DOI: 10.1126/science.1235038

PubMed ID: 19457867

Title: Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division.

PubMed ID: 19457867

DOI: 10.1074/jbc.m109.000885

Sequence Information:

Length: 1171
Mass: 133686
Checksum: 95347A854CABC7CF
Sequence:

MERHRARALG RDSKSSRRKG LQSAPPAGPY EPGEKRPKLH LNIRTLTDDM LDKFASIRIP 
GSKKERPPLP HLKTVSGISD SSSLSSETME NNPKALPESE VLKLFEKMME DMNLNEDKKA 
PLREKDFGIK KEMVMQYINT ASKTGSLRSS RQISPQEFLH ELKMGYTDER LFTYLESLRV 
SLTSHPVSWV QSFGHEGLGL LLDILEKLIN GQIQEKVVKK TQHKVIQCLR ALMNTQYGLE 
RIMSDKRSLS LLAKAMDPRQ PAMMADVVKL LSAVCIVGEE SILEEVLEAL TSAGEERKID 
RFFSIVEGLR HNSVNLQVAC MQLINALVTS PDDLDFRLHL RNEFMRCGLK EILPNLKGIK 
NDGLDIQLKV FDEHKEEDLS EFFHRLEDIR AELDEASDVY SMLWDTVKET RAEGHFLSIL 
QHLLLIRNDR FIREQYFKLI DECVSQIVLH RDGTDPDFTY RKRLDLDLSQ FVDVCIDQAK 
LDEWEEKASE HCKKFEKECT DHQETQAQLQ KREAKINELQ AELQAFKSQF GALPPGTKIP 
LQPSVEGEAG PSALPPAPPA LSGGVPPPPP PPPPPPPPLP GMPMPFGGPV PPPPPLGFLG 
GQSSIPLNLP FGLKPKKEFK PEISMRRLNW LKIGPNEMSE NCFWIKVNEN KYENRDLLCK 
LENTFCCQEK EKRNTNDFDE KKVIKKRMKE LKFLDPKIAQ NLSIFLSSFR VPYEKIRTMI 
LEVDETQLSE SMIQNLIKHL PDEEQLKSLS QFRSDYNSLC EPEQFAVVMS NVKRLRPRLS 
AILFKLQFEE QVNNIKPDIM AVSTACEEIK KSKGFSKLLE LVLLMGNYMN AGSRNAQTFG 
FDLSSLCKLK DTKSADQKTT LLHFLVDVCE EKHADILHFV DDLAHLDKAS RVSVEMLEKN 
VKQMGRQLQQ LEKNLETFPP PEDLHDKFVI KMSSFVISAN EQYEKLSTLL GSMTQLYQSI 
MGYYAVDMKK VSVEEFFNDL NNFRTSFMLA LKENIKKREA AEKEKRARIA KERAEKERLE 
RQQEKKRLLE MKTEGDETGV MDSLLEALQS GAAFRDRRKR TPKLKDIRQS LSPMSQRPVL 
KVCNHENQKM QLTEGSRPHH SINCNSTRTP VAKELNYNLD THASTGRIKA VEKEACNAES 
NKKKEMELLG SVAKSESVPE VEALLARLRA L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Diaph3

Associated with

Other Information

Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. PubMed ID: 9535835

Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. PubMed ID: 10678165

mDia2 shuttles between the nucleus and the cytoplasm through the importin-{alpha}/{beta}- and CRM1-mediated nuclear transport mechanism. PubMed ID: 19117945