Details for: Cib2

Gene ID: 56506

Symbol: Cib2

Ensembl ID: ENSMUSG00000037493

Description: calcium and integrin binding family member 2

Associated with

Other Information

Genular Protein ID: 3271261632

Symbol: CIB2_MOUSE

Name: Calcium and integrin-binding family member 2

UniProtKB Accession Codes:

Q9Z309

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 9 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9931475

Title: Structure, expression profile and chromosomal location of an isolog of DNA-PKcs interacting protein (KIP) gene.

PubMed ID: 9931475

DOI: 10.1016/s0167-4781(98)00253-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18611855

Title: Cib2 binds integrin alpha7Bbeta1D and is reduced in laminin alpha2 chain-deficient muscular dystrophy.

PubMed ID: 18611855

DOI: 10.1074/jbc.m801166200

PubMed ID: 18989529

Title: Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members.

PubMed ID: 18989529

DOI: 10.1160/th08-06-0351

PubMed ID: 23023331

Title: Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.

PubMed ID: 23023331

DOI: 10.1038/ng.2426

PubMed ID: 29084757

Title: CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival.

PubMed ID: 29084757

DOI: 10.15252/emmm.201708087

PubMed ID: 29255404

Title: Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice.

PubMed ID: 29255404

DOI: 10.3389/fnmol.2017.00401

PubMed ID: 28663585

Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.

PubMed ID: 28663585

DOI: 10.1038/s41467-017-00061-1

PubMed ID: 34089643

Title: CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.

PubMed ID: 34089643

DOI: 10.1016/j.neuron.2021.05.007

Sequence Information:

  • Length: 187
  • Mass: 21704
  • Checksum: D21D21DCBD0B6F5C
  • Sequence:
    • MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HARFYELAPN LVPMDYRKSP IVHVPMSLII 
QMPELRENPF KERIVEAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD 
NFICKEDLEM TLARLTKSEL EEDEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL 
STFHIRI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.