Details for: SLC2A9

Gene ID: 56606

Symbol: SLC2A9

Ensembl ID: ENSG00000109667

Description: solute carrier family 2 member 9

Associated with

Other Information

Genular Protein ID: 1667173740

Symbol: GTR9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10860667

Title: Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9).

PubMed ID: 10860667

DOI: 10.1006/geno.2000.6195

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11991658

Title: Human articular chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9.

PubMed ID: 11991658

DOI: 10.1006/cbir.2001.0850

PubMed ID: 14739288

Title: Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking.

PubMed ID: 14739288

DOI: 10.1074/jbc.m312226200

PubMed ID: 17710649

Title: A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.

PubMed ID: 17710649

DOI: 10.1080/09687680701298143

PubMed ID: 18842065

Title: SLC2A9 is a high-capacity urate transporter in humans.

PubMed ID: 18842065

DOI: 10.1371/journal.pmed.0050197

PubMed ID: 22647630

Title: Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses.

PubMed ID: 22647630

DOI: 10.1152/ajprenal.00134.2012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24409316

Title: Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells.

PubMed ID: 24409316

DOI: 10.1371/journal.pone.0084996

PubMed ID: 28083649

Title: Reassessment of GLUT7 and GLUT9 as putative fructose and glucose transporters.

PubMed ID: 28083649

DOI: 10.1007/s00232-016-9945-7

PubMed ID: 28117388

Title: Identification of Key Residues for Urate Specific Transport in Human Glucose Transporter 9 (hSLC2A9).

PubMed ID: 28117388

DOI: 10.1038/srep41167

PubMed ID: 36749388

Title: Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations.

PubMed ID: 36749388

DOI: 10.1007/s00424-023-02792-1

PubMed ID: 19026395

Title: Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia.

PubMed ID: 19026395

DOI: 10.1016/j.ajhg.2008.11.001

PubMed ID: 18701466

Title: Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans.

PubMed ID: 18701466

DOI: 10.1074/jbc.c800156200

PubMed ID: 18327256

Title: SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.

PubMed ID: 18327256

DOI: 10.1038/ng.107

PubMed ID: 18327257

Title: SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.

PubMed ID: 18327257

DOI: 10.1038/ng.106

PubMed ID: 19926891

Title: Homozygous SLC2A9 mutations cause severe renal hypouricemia.

PubMed ID: 19926891

DOI: 10.1681/asn.2009040406

PubMed ID: 22132964

Title: Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2).

PubMed ID: 22132964

DOI: 10.1080/15257770.2011.623685

PubMed ID: 21810765

Title: Two novel homozygous SLC2A9 mutations cause renal hypouricemia type 2.

PubMed ID: 21810765

DOI: 10.1093/ndt/gfr419

PubMed ID: 22527535

Title: Acute kidney injury in two children caused by renal hypouricaemia type 2.

PubMed ID: 22527535

DOI: 10.1007/s00467-012-2174-0

PubMed ID: 25268603

Title: Complex analysis of urate transporters SLC2A9, SLC22A12 and functional characterization of non-synonymous allelic variants of GLUT9 in the Czech population: no evidence of effect on hyperuricemia and gout.

PubMed ID: 25268603

DOI: 10.1371/journal.pone.0107902

PubMed ID: 29967582

Title: Human Mutations in SLC2A9 (Glut9) Affect Transport Capacity for Urate.

PubMed ID: 29967582

DOI: 10.3389/fphys.2018.00476

Sequence Information:

  • Length: 540
  • Mass: 58702
  • Checksum: EEA40123DB5233B4
  • Sequence:
  • MARKQNRNSK ELGLVPLTDD TSHAGPPGPG RALLECDHLR SGVPGGRRRK DWSCSLLVAS 
    LAGAFGSSFL YGYNLSVVNA PTPYIKAFYN ESWERRHGRP IDPDTLTLLW SVTVSIFAIG 
    GLVGTLIVKM IGKVLGRKHT LLANNGFAIS AALLMACSLQ AGAFEMLIVG RFIMGIDGGV 
    ALSVLPMYLS EISPKEIRGS LGQVTAIFIC IGVFTGQLLG LPELLGKEST WPYLFGVIVV 
    PAVVQLLSLP FLPDSPRYLL LEKHNEARAV KAFQTFLGKA DVSQEVEEVL AESRVQRSIR 
    LVSVLELLRA PYVRWQVVTV IVTMACYQLC GLNAIWFYTN SIFGKAGIPP AKIPYVTLST 
    GGIETLAAVF SGLVIEHLGR RPLLIGGFGL MGLFFGTLTI TLTLQDHAPW VPYLSIVGIL 
    AIIASFCSGP GGIPFILTGE FFQQSQRPAA FIIAGTVNWL SNFAVGLLFP FIQKSLDTYC 
    FLVFATICIT GAIYLYFVLP ETKNRTYAEI SQAFSKRNKA YPPEEKIDSA VTDGKINGRP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.