Trim17 | ENSMUSG00000036964 | NCBI 56631

Details for: Trim17

Gene ID: 56631

Symbol: Trim17

Ensembl ID: ENSMUSG00000036964

Description: tripartite motif-containing 17

Associated with

Autophagy
(GO:0006914)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Lysosome
(GO:0005764)
Metal ion binding
(GO:0046872)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein autoubiquitination
(GO:0051865)
Protein ubiquitination
(GO:0016567)
Regulation of gene expression
(GO:0010468)
Regulation of protein localization
(GO:0032880)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase TRIM17

Genular Protein ID: 2392686117

Symbol: TRI17_MOUSE

Name: E3 ubiquitin-protein ligase TRIM17

UniProtKB Accession Codes:

Q7TPM3 A2AB82 Q99PP8

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 20559321

Title: Trim17, a novel E3 ubiquitin-ligase, initiates neuronal apoptosis.

PubMed ID: 20559321

DOI: 10.1038/cdd.2010.73

PubMed ID: 22976837

Title: Trim17-mediated ubiquitination and degradation of Mcl-1 initiate apoptosis in neurons.

PubMed ID: 22976837

DOI: 10.1038/cdd.2012.124

PubMed ID: 25215946

Title: Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17.

PubMed ID: 25215946

DOI: 10.1038/cdd.2014.141

PubMed ID: 30485814

Title: The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate alpha-Synuclein Expression by Regulating ZSCAN21.

PubMed ID: 30485814

DOI: 10.1016/j.celrep.2018.11.002

Sequence Information:

Length: 477
Mass: 54863
Checksum: E05066304224A1AE
Sequence:

MDAVELARRL QEEATCSICL DYFTDPVMTA CGHNFCRECI QMSWEKGKVK KGKKKQKGSF 
PCPECREMSP QRNLRPNRLL TKVAEMARQH PGLQKRDLCQ AHQEPLKLFC QDDQSPICVV 
CREAQEHRMH RVLPLDEAAR EYKLKLEEDI KYLREEMMKT ETLQAKEEQT LTEWQERVKE 
RRERILEEFQ KVVLFLVEEE RRILQVLKKE EEDTLGKLQD SKASLDHQSR SLDLILLQLE 
ERSQQEPLQM LQDVKDTLNR KESFSVQYPE VVLPAAIKTL CRVPGQIEVL KSFQEDVMPD 
PSSAYPYLLL YESRQRRYLS PPPEGSAPYS KDRFVAYPCA VGQKSFSSGR HYWEVGMNLT 
GDALWALGVC RDNVSRKDRV LKSPENGFWV VQLSKGKKQL SLLPNSTLVT LTEPPSHMGI 
FLDFQAGEVS FYSVNDGSHL HSFSQAAFPG PLLPFFCLGA PKSGQMVIST VTMWVKG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Trim17

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The tripartite motif family identifies cell compartments. PubMed ID: 11331580

Trim17, a novel E3 ubiquitin-ligase, initiates neuronal apoptosis. PubMed ID: 20559321

Trim17-mediated ubiquitination and degradation of Mcl-1 initiate apoptosis in neurons. PubMed ID: 22976837

Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17. PubMed ID: 25215946

The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate alpha-Synuclein Expression by Regulating ZSCAN21. PubMed ID: 30485814