Fgf21 | ENSMUSG00000030827 | NCBI 56636

Details for: Fgf21

Gene ID: 56636

Symbol: Fgf21

Ensembl ID: ENSMUSG00000030827

Description: fibroblast growth factor 21

Associated with

Cellular hexose transport
(R-MMU-189200)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of small molecules
(R-MMU-382551)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Growth factor activity
(GO:0008083)
Negative regulation of endothelial cell apoptotic process
(GO:2000352)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of mapkkk cascade by fibroblast growth factor receptor signaling pathway
(GO:0090080)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of triglyceride catabolic process
(GO:0010898)
Regulation of cell migration
(GO:0030334)

Other Information

Proteins

Fibroblast growth factor 21

Genular Protein ID: 1236806001

Symbol: FGF21_MOUSE

Name: Fibroblast growth factor 21

UniProtKB Accession Codes:

Q9JJN1

Database IDs:

Citations:

PubMed ID: 10858549

Title: Identification of a novel FGF, FGF-21, preferentially expressed in the liver.

PubMed ID: 10858549

DOI: 10.1016/s0167-4781(00)00067-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15902306

Title: FGF-21 as a novel metabolic regulator.

PubMed ID: 15902306

DOI: 10.1172/jci23606

PubMed ID: 30389664

Title: HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination.

PubMed ID: 30389664

DOI: 10.15252/embj.201898942

PubMed ID: 30605666

Title: CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance.

PubMed ID: 30605666

DOI: 10.1016/j.celrep.2018.12.031

Sequence Information:

Length: 210
Mass: 23237
Checksum: AE02AABA6477E6F0
Sequence:

MEWMRSRVGT LGLWVRLLLA VFLLGVYQAY PIPDSSPLLQ FGGQVRQRYL YTDDDQDTEA 
HLEIREDGTV VGAAHRSPES LLELKALKPG VIQILGVKAS RFLCQQPDGA LYGSPHFDPE 
ACSFRELLLE DGYNVYQSEA HGLPLRLPQK DSPNQDATSW GPVRFLPMPG LLHEPQDQAG 
FLPPEPPDVG SSDPLSMVEP LQGRSPSYAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgf21

Associated with

Other Information

Identification of a novel FGF, FGF-21, preferentially expressed in the liver. PubMed ID: 10858549

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

FGF-21 as a novel metabolic regulator. PubMed ID: 15902306

HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination. PubMed ID: 30389664