Details for: BCCIP

Gene ID: 56647

Symbol: BCCIP

Ensembl ID: ENSG00000107949

Description: BRCA2 and CDKN1A interacting protein

Associated with

Other Information

Genular Protein ID: 919418361

Symbol: BCCIP_HUMAN

Name: BRCA2 and CDKN1A-interacting protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10878006

Title: TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase.

PubMed ID: 10878006

DOI: 10.1074/jbc.m003031200

PubMed ID: 12527204

Title: Genomic structure of the human BCCIP gene and its expression in cancer.

PubMed ID: 12527204

DOI: 10.1016/s0378-1119(02)01098-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11313963

Title: Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2.

PubMed ID: 11313963

DOI: 10.1038/sj.onc.1204098

PubMed ID: 14726710

Title: Inhibition of G1 to S cell cycle progression by BCCIP beta.

PubMed ID: 14726710

PubMed ID: 15539944

Title: BCCIP functions through p53 to regulate the expression of p21Waf1/Cip1.

PubMed ID: 15539944

DOI: 10.4161/cc.3.11.1213

PubMed ID: 15713648

Title: The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair.

PubMed ID: 15713648

DOI: 10.1128/mcb.25.5.1949-1957.2005

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17947333

Title: BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage.

PubMed ID: 17947333

DOI: 10.1093/nar/gkm732

PubMed ID: 18440304

Title: LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells.

PubMed ID: 18440304

DOI: 10.1016/j.bbrc.2008.04.084

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28931820

Title: The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.

PubMed ID: 28931820

DOI: 10.1038/s41467-017-00578-5

PubMed ID: 28394342

Title: Regulation of spindle integrity and mitotic fidelity by BCCIP.

PubMed ID: 28394342

DOI: 10.1038/onc.2017.92

Sequence Information:

  • Length: 314
  • Mass: 35979
  • Checksum: 203CA32F7BE0A806
  • Sequence:
  • MASRSKRRAV ESGVPQPPDP PVQRDEEEEK EVENEDEDDD DSDKEKDEED EVIDEEVNIE 
    FEAYSLSDND YDGIKKLLQQ LFLKAPVNTA ELTDLLIQQN HIGSVIKQTD VSEDSNDDMD 
    EDEVFGFISL LNLTERKGTQ CVEQIQELVL RFCEKNCEKS MVEQLDKFLN DTTKPVGLLL 
    SERFINVPPQ IALPMYQQLQ KELAGAHRTN KPCGKCYFYL LISKTFVEAG KNNSKKKPSN 
    KKKAALMFAN AEEEFFYEKA ILKFNYSVQE ESDTCLGGKW SFDDVPMTPL RTVMLIPGDK 
    MNEIMDKLKE YLSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.