Details for: SUCNR1

Gene ID: 56670

Symbol: SUCNR1

Ensembl ID: ENSG00000198829

Description: succinate receptor 1

Associated with

Other Information

Genular Protein ID: 510454432

Symbol: SUCR1_HUMAN

Name: G-protein coupled receptor 91

UniProtKB Accession Codes:

Q9BXA5 A8K305 Q8TDQ8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EMBL 7 Ensembl 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 neXtProt 1

Citations:

PubMed ID: 11273702

Title: An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors.

PubMed ID: 11273702

DOI: 10.1006/jmbi.2001.4520

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15141213

Title: Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors.

PubMed ID: 15141213

DOI: 10.1038/nature02488

PubMed ID: 18820681

Title: Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.

PubMed ID: 18820681

DOI: 10.1038/ni.1657

PubMed ID: 23770096

Title: Succinate receptor GPR91, a Galpha(i) coupled receptor that increases intracellular calcium concentrations through PLCbeta.

PubMed ID: 23770096

DOI: 10.1016/j.febslet.2013.05.067

PubMed ID: 34133934

Title: Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.

PubMed ID: 34133934

DOI: 10.1016/j.celrep.2021.109246

Sequence Information:

  • Length: 334
  • Mass: 38698
  • Checksum: 33146E1AD87F0E81
  • Sequence:
    • MLGIMAWNAT CKNWLAAEAA LEKYYLSIFY GIEFVVGVLG NTIVVYGYIF SLKNWNSSNI 
YLFNLSVSDL AFLCTLPMLI RSYANGNWIY GDVLCISNRY VLHANLYTSI LFLTFISIDR 
YLIIKYPFRE HLLQKKEFAI LISLAIWVLV TLELLPILPL INPVITDNGT TCNDFASSGD 
PNYNLIYSMC LTLLGFLIPL FVMCFFYYKI ALFLKQRNRQ VATALPLEKP LNLVIMAVVI 
FSVLFTPYHV MRNVRIASRL GSWKQYQCTQ VVINSFYIVT RPLAFLNSVI NPVFYFLLGD 
HFRDMLMNQL RHNFKSLTSF SRWAHELLLS FREK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.