Mlycd | ENSMUSG00000074064 | NCBI 56690

Details for: Mlycd

Gene ID: 56690

Symbol: Mlycd

Ensembl ID: ENSMUSG00000074064

Description: malonyl-CoA decarboxylase

Associated with

Beta-oxidation of very long chain fatty acids
(R-MMU-390247)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Peroxisomal lipid metabolism
(R-MMU-390918)
Peroxisomal protein import
(R-MMU-9033241)
Protein localization
(R-MMU-9609507)
Acetyl-coa biosynthetic process
(GO:0006085)
Carboxy-lyase activity
(GO:0016831)
Cytoplasm
(GO:0005737)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Fatty acid oxidation
(GO:0019395)
Identical protein binding
(GO:0042802)
Lipid metabolic process
(GO:0006629)
Lyase activity
(GO:0016829)
Malonyl-coa catabolic process
(GO:2001294)
Malonyl-coa decarboxylase activity
(GO:0050080)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Positive regulation of fatty acid oxidation
(GO:0046321)
Protein binding
(GO:0005515)
Regulation of fatty acid beta-oxidation
(GO:0031998)
Regulation of fatty acid oxidation
(GO:0046320)
Regulation of glucose metabolic process
(GO:0010906)
Response to ischemia
(GO:0002931)

Other Information

Proteins

DCMC_MOUSE

Genular Protein ID: 1295707797

Symbol: DCMC_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q99J39 Q7TNL6

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17030679

Title: Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury.

PubMed ID: 17030679

DOI: 10.1161/circulationaha.106.642009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23746352

Title: SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.

PubMed ID: 23746352

DOI: 10.1016/j.molcel.2013.05.012

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 492
Mass: 54736
Checksum: CEBDA62714A21DC1
Sequence:

MRGLGPGLRA RRLLPLRSPP RPPGPRGRRL CGGLAASAMD ELLRRAVPPT PAYELREKTP 
APAEGQCADF VSFYGGLAEA SQRAELLGRL AQGFGVDHGQ VAEQSAGVLQ LRQQAREAAV 
LLQAEDRLRY ALVPRYRGLF HHISKLDGGV RFLVQLRADL LEAQALKLVE GPHVREMNGV 
LKSMLSEWFS SGFLNLERVT WHSPCEVLQK ISECEAVHPV KNWMDMKRRV GPYRRCYFFS 
HCSTPGEPLV VLHVALTGDI SNNIQGIVKE CPPTETEERN RIAAAIFYSI SLTQQGLQGV 
ELGTFLIKRV VKELQKEFPQ LGAFSSLSPI PGFTKWLLGL LNVQGKEHGR NELFTDSECQ 
EISAVTGNPV HESLKGFLSS GEWVKSEKLT QALQGPLMRL CAWYLYGEKH RGYALNPVAN 
FHLQNGAVMW RINWMADSSL KGLTSSCGLM VNYRYYLEET GPNSISYLGS KNIKASEQIL 
SLVAQFQNNS KL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mlycd

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury. PubMed ID: 17030679

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. PubMed ID: 23746352

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753