Details for: Clcf1

Gene ID: 56708

Symbol: Clcf1

Ensembl ID: ENSMUSG00000040663

Description: cardiotrophin-like cytokine factor 1

Associated with

  • Cytokine signaling in immune system
    (R-MMU-1280215)
  • Il-6-type cytokine receptor ligand interactions
    (R-MMU-6788467)
  • Immune system
    (R-MMU-168256)
  • Interleukin-6 family signaling
    (R-MMU-6783589)
  • Signaling by interleukins
    (R-MMU-449147)
  • B cell differentiation
    (GO:0030183)
  • Cell surface receptor signaling pathway
    (GO:0007166)
  • Ciliary neurotrophic factor receptor binding
    (GO:0005127)
  • Cntfr-clcf1 complex
    (GO:0097059)
  • Crlf-clcf1 complex
    (GO:0097058)
  • Cytokine activity
    (GO:0005125)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Negative regulation of motor neuron apoptotic process
    (GO:2000672)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Positive regulation of astrocyte differentiation
    (GO:0048711)
  • Positive regulation of b cell proliferation
    (GO:0030890)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of corticotropin-releasing hormone secretion
    (GO:0051466)
  • Positive regulation of immunoglobulin production
    (GO:0002639)
  • Positive regulation of isotype switching to ige isotypes
    (GO:0048295)
  • Positive regulation of type 2 immune response
    (GO:0002830)
  • Positive regulation of tyrosine phosphorylation of stat protein
    (GO:0042531)
  • Protein binding
    (GO:0005515)
  • Receptor signaling pathway via jak-stat
    (GO:0007259)
  • Regulation of erk1 and erk2 cascade
    (GO:0070372)
  • Regulation of inflammatory response
    (GO:0050727)
  • Regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051896)
  • Signaling receptor binding
    (GO:0005102)

Other Information

Genular Protein ID: 2956047452

Symbol: CLCF1_MOUSE

Name: Cardiotrophin-like cytokine factor 1

UniProtKB Accession Codes:

Q9QZM3 Q3SXK2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEMBL 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 3 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10500198

Title: Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family.

PubMed ID: 10500198

DOI: 10.1073/pnas.96.20.11458

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 225
  • Mass: 25261
  • Checksum: 68B1FEAAB7F1A950
  • Sequence:
    • MDLRAGDSWG MLACLCTVLW HLPAVPALNR TGDPGPGPSI QKTYDLTRYL EHQLRSLAGT 
YLNYLGPPFN EPDFNPPRLG AETLPRATVN LEVWRSLNDR LRLTQNYEAY SHLLCYLRGL 
NRQAATAELR RSLAHFCTSL QGLLGSIAGV MATLGYPLPQ PLPGTEPAWA PGPAHSDFLQ 
KMDDFWLLKE LQTWLWRSAK DFNRLKKKMQ PPAASVTLHL EAHGF

Genular Protein ID: 1846265671

Symbol: Q3TM06_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TM06

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Google 1 InterPro 2 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 215
  • Mass: 24172
  • Checksum: 0290FAB37D37DE1A
  • Sequence:
    • MLACLCTVLW HLPAVPALNR TGDPGPGPSI QKTYDLTRYL EHQLRSLAGT YLNYLGPPFN 
EPDFNPPRLG AETLPRATVN LEVWRSLNDR LRLTQNYEAY SHLLCYLRGL NRQAATAELR 
RSLAHFCTSL QGLLGSIAGV MATLGYPLPQ PLPGTEPAWA PGPAHSDFLQ KMDDFWLLKE 
LQTWLWRSAK DFNRLKKKMQ PPAASVTLHL EAHGF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.