Mlst8 | ENSMUSG00000024142 | NCBI 56716

Details for: Mlst8

Gene ID: 56716

Symbol: Mlst8

Ensembl ID: ENSMUSG00000024142

Description: MTOR associated protein, LST8 homolog (S. cerevisiae)

Associated with

Adaptive immune system
(R-MMU-1280218)
Amino acids regulate mtorc1
(R-MMU-9639288)
Autophagy
(R-MMU-9612973)
Cd28 co-stimulation
(R-MMU-389356)
Cd28 dependent pi3k/akt signaling
(R-MMU-389357)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to heat stress
(R-MMU-3371556)
Cellular response to starvation
(R-MMU-9711097)
Costimulation by the cd28 family
(R-MMU-388841)
Energy dependent regulation of mtor by lkb1-ampk
(R-MMU-380972)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hsf1-dependent transactivation
(R-MMU-3371571)
Immune system
(R-MMU-168256)
Intracellular signaling by second messengers
(R-MMU-9006925)
Macroautophagy
(R-MMU-1632852)
Mtorc1-mediated signalling
(R-MMU-166208)
Mtor signalling
(R-MMU-165159)
Pip3 activates akt signaling
(R-MMU-1257604)
Pten regulation
(R-MMU-6807070)
Regulation of pten gene transcription
(R-MMU-8943724)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 degradation
(R-MMU-6804757)
Regulation of tp53 expression and degradation
(R-MMU-6806003)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated vascular permeability
(R-MMU-5218920)
Cellular response to hypoxia
(GO:0071456)
Cellular response to nutrient levels
(GO:0031669)
Cellular response to osmotic stress
(GO:0071470)
Cytoplasm
(GO:0005737)
Cytoskeleton organization
(GO:0007010)
Dna damage response
(GO:0006974)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of autophagy
(GO:0010507)
Positive regulation of actin filament polymerization
(GO:0030838)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of glycolytic process
(GO:0045821)
Positive regulation of lipid biosynthetic process
(GO:0046889)
Positive regulation of pentose-phosphate shunt
(GO:1905857)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of tor signaling
(GO:0032008)
Protein serine/threonine kinase activator activity
(GO:0043539)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of gtpase activity
(GO:0043087)
Torc1 complex
(GO:0031931)
Torc1 signaling
(GO:0038202)
Torc2 complex
(GO:0031932)
Tor signaling
(GO:0031929)

Other Information

Proteins

G protein beta subunit-like
A0A3Q4EC26_MOUSE

Genular Protein ID: 3906584017

Symbol: LST8_MOUSE

Name: G protein beta subunit-like

UniProtKB Accession Codes:

Q9DCJ1 Q8BNG8 Q8C882 Q9JKK6

Database IDs:

Citations:

PubMed ID: 11182770

Title: Insulin regulation of a novel WD-40 repeat protein in adipocytes.

PubMed ID: 11182770

DOI: 10.1677/joe.0.1680325

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12718876

Title: GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.

PubMed ID: 12718876

DOI: 10.1016/s1097-2765(03)00114-x

PubMed ID: 17141160

Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

PubMed ID: 17141160

DOI: 10.1016/j.devcel.2006.10.007

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20801936

Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

PubMed ID: 20801936

DOI: 10.1101/gad.1956410

Sequence Information:

Length: 326
Mass: 35851
Checksum: 2F6E75383905667A
Sequence:

MNTTPGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSQVNALEI TPDRSMIAAA 
GYQHIRMYDL NSNNPNPIIS YDGVSKNIAS VGFHEDGRWM YTGGEDCTAR IWDLRSRNLQ 
CQRIFQVNAP INCVCLHPNQ AELIVGDQSG AIHIWDLKTD HNEQLIPEPE SSITSAHIDP 
DASYMAAVNS AGNCYVWNLT GGIGDDVTQL IPKTKIPAHT RYALQCRFSP DSTLLATCSA 
DQTCKIWRTS NFSLMTELSI KSSNPGESSR GWMWGCAFSG DSQYIVTASS DNLARLWCVE 
TGEIKREYGG HQKAVVCLAF NDSVLG

Genular Protein ID: 2611975042

Symbol: A0A3Q4EC26_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A3Q4EC26

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 260
Mass: 28675
Checksum: 3F6E3AD0E4C0E954
Sequence:

MYDLNSNNPN PIISYDGVSK NIASVGFHED GRWMYTGGED CTARIWDLRS RNLQCQRIFQ 
VNAPINCVCL HPNQAELIVG DQSGAIHIWD LKTDHNEQLI PEPESSITSA HIDPDASYMA 
AVNSAGNCYV WNLTGGIGDD VTQLIPKTKI PAHTRYALQC RFSPDSTLLA TCSADQTCKI 
WRTSNFSLMT ELSIKSSNPG ESSRGWMWGC AFSGDSQYIV TASSDNLARL WCVETGEIKR 
EYGGHQKAVV CLAFNDSVLG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mlst8

Associated with

Other Information

Insulin regulation of a novel WD-40 repeat protein in adipocytes. PubMed ID: 11182770

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. PubMed ID: 12718876

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. PubMed ID: 17141160

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. PubMed ID: 20801936

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303