Details for: Lat2

Gene ID: 56743

Symbol: Lat2

Ensembl ID: ENSMUSG00000040751

Description: linker for activation of T cells family, member 2

Associated with

Other Information

Genular Protein ID: 2250587045

Symbol: NTAL_MOUSE

Name: Linker for activation of T-cells family member 2

UniProtKB Accession Codes:

Q9JHL0 Q3UYF6 Q9JJ29

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 10 Ensembl 3 ExpressionAtlas 1 GO 9 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 5 SAM 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 2 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 11124535

Title: Divergent human and mouse orthologs of a novel gene (WBSCR15/Wbscr15) reside within the genomic interval commonly deleted in Williams syndrome.

PubMed ID: 11124535

DOI: 10.1159/000056790

PubMed ID: 11003705

Title: Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23.

PubMed ID: 11003705

DOI: 10.1007/s003350010166

PubMed ID: 12514734

Title: LAB: a new membrane-associated adaptor molecule in B cell activation.

PubMed ID: 12514734

DOI: 10.1038/ni882

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15539154

Title: Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes.

PubMed ID: 15539154

DOI: 10.1016/j.immuni.2004.09.007

PubMed ID: 15477350

Title: Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL.

PubMed ID: 15477350

DOI: 10.1084/jem.20041223

PubMed ID: 15477348

Title: Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.

PubMed ID: 15477348

DOI: 10.1084/jem.20041213

PubMed ID: 15899851

Title: Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function.

PubMed ID: 15899851

DOI: 10.1128/mcb.25.11.4455-4465.2005

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

  • Length: 203
  • Mass: 22876
  • Checksum: 1B21A87D8FBAE097
  • Sequence:
    • MSAELELLWP VSGLLLLLLG ATAWLCVHCS RPGVKRNEKI YEQRNRQENA QSSAAAQTYS 
LARQVWPGPQ MDTAPNKSFE RKNKMLFSHL EGPESPRYQN FYKGSNQEPD AAYVDPIPTN 
YYNWGCFQKP SEDDDSNSYE NVLVCKPSTP ESGVEDFEDY QNSVSIHQWR ESKRTMGAPM 
SLSGSPDEEP DYVNGDVAAA ENI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.