Details for: FMN2

Gene ID: 56776

Symbol: FMN2

Ensembl ID: ENSG00000155816

Description: formin 2

Associated with

Other Information

Genular Protein ID: 2614169064

Symbol: FMN2_HUMAN

Name: Formin-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 10781961

Title: Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system.

PubMed ID: 10781961

DOI: 10.1016/s0925-4773(00)00276-8

PubMed ID: 20082305

Title: Effects of genistein on beta-catenin signaling and subcellular distribution of actin-binding proteins in human umbilical CD105-positive stromal cells.

PubMed ID: 20082305

DOI: 10.1002/jcp.22051

PubMed ID: 22330775

Title: Differential role of actin-binding proteins in controlling the adipogenic differentiation of human CD105-positive Wharton's Jelly cells.

PubMed ID: 22330775

DOI: 10.1016/j.bbagen.2012.01.014

PubMed ID: 23375502

Title: Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21.

PubMed ID: 23375502

DOI: 10.1016/j.molcel.2012.12.023

PubMed ID: 25480035

Title: Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability.

PubMed ID: 25480035

DOI: 10.1016/j.ajhg.2014.10.016

PubMed ID: 26287480

Title: DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-1/2 that promotes efficient DNA repair.

PubMed ID: 26287480

DOI: 10.7554/elife.07735

PubMed ID: 21705804

Title: Molecular basis of actin nucleation factor cooperativity: crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND)*formin-2 formin SPIR interaction motif (FSI) complex.

PubMed ID: 21705804

DOI: 10.1074/jbc.m111.257782

PubMed ID: 21730168

Title: Structure and function of the interacting domains of Spire and Fmn-family formins.

PubMed ID: 21730168

DOI: 10.1073/pnas.1105703108

Sequence Information:

  • Length: 1722
  • Mass: 180106
  • Checksum: 26525AC7868A949C
  • Sequence:
  • MGNQDGKLKR SAGDALHEGG GGAEDALGPR DVEATKKGSG GKKALGKHGK GGGGGGGGGE 
    SGKKKSKSDS RASVFSNLRI RKNLSKGKGA GGSREDVLDS QALQTGELDS AHSLLTKTPD 
    LSLSADEAGL SDTECADPFE VTGPGGPGPA EARVGGRPIA EDVETAAGAQ DGQRTSSGSD 
    TDIYSFHSAT EQEDLLSDIQ QAIRLQQQQQ QQLQLQLQQQ QQQQQLQGAE EPAAPPTAVS 
    PQPGAFLGLD RFLLGPSGGA GEAPGSPDTE QALSALSDLP ESLAAEPREP QQPPSPGGLP 
    VSEAPSLPAA QPAAKDSPSS TAFPFPEAGP GEEAAGAPVR GAGDTDEEGE EDAFEDAPRG 
    SPGEEWAPEV GEDAPQRLGE EPEEEAQGPD APAAASLPGS PAPSQRCFKP YPLITPCYIK 
    TTTRQLSSPN HSPSQSPNQS PRIKRRPEPS LSRGSRTALA SVAAPAKKHR ADGGLAAGLS 
    RSADWTEELG ARTPRVGGSA HLLERGVASD SGGGVSPALA AKASGAPAAA DGFQNVFTGR 
    TLLEKLFSQQ ENGPPEEAEK FCSRIIAMGL LLPFSDCFRE PCNQNAQTNA ASFDQDQLYT 
    WAAVSQPTHS LDYSEGQFPR RVPSMGPPSK PPDEEHRLED AETESQSAVS ETPQKRSDAV 
    QKEVVDMKSE GQATVIQQLE QTIEDLRTKI AELERQYPAL DTEVASGHQG LENGVTASGD 
    VCLEALRLEE KEVRHHRILE AKSIQTSPTE EGGVLTLPPV DGLPGRPPCP PGAESGPQTK 
    FCSEISLIVS PRRISVQLDS HQPTQSISQP PPPPSLLWSA GQGQPGSQPP HSISTEFQTS 
    HEHSVSSAFK NSCNIPSPPP LPCTESSSSM PGLGMVPPPP PPLPGMTVPT LPSTAIPQPP 
    PLQGTEMLPP PPPPLPGAGI PPPPPLPGAG ILPLPPLPGA GIPPPPPLPG AAIPPPPPLP 
    GAGIPLPPPL PGAGIPPPPP LPGAGIPPPP PLPGAGIPPP PPLPGAGIPP PPPLPGAGIP 
    PPPPLPGAGI PPPPPLPGAG IPPPPPLPGA GIPPPPPLPG AGIPPPPPLP GAGIPPPPPL 
    PGAGIPPPPP LPGAGIPPPP PLPGVGIPPP PPLPGAGIPP PPPLPGAGIP PPPPLPGAGI 
    PPPPPLPRVG IPPPPPLPGA GIPPPPPLPG AGIPPPPPLP GVGIPPPPPL PGVGIPPPPP 
    LPGAGIPPPP PLPGMGIPPA PAPPLPPPGT GIPPPPLLPV SGPPLLPQVG SSTLPTPQVC 
    GFLPPPLPSG LFGLGMNQDK GSRKQPIEPC RPMKPLYWTR IQLHSKRDSS TSLIWEKIEE 
    PSIDCHEFEE LFSKTAVKER KKPISDTISK TKAKQVVKLL SNKRSQAVGI LMSSLHLDMK 
    DIQHAVVNLD NSVVDLETLQ ALYENRAQSD ELEKIEKHGR SSKDKENAKS LDKPEQFLYE 
    LSLIPNFSER VFCILFQSTF SESICSIRRK LELLQKLCET LKNGPGVMQV LGLVLAFGNY 
    MNGGNKTRGQ ADGFGLDILP KLKDVKSSDN SRSLLSYIVS YYLRNFDEDA GKEQCLFPLP 
    EPQDLFQASQ MKFEDFQKDL RKLKKDLKAC EVEAGKVYQV SSKEHMQPFK ENMEQFIIQA 
    KIDQEAEENS LTETHKCFLE TTAYFFMKPK LGEKEVSPNA FFSIWHEFSS DFKDFWKKEN 
    KLLLQERVKE AEEVCRQKKG KSLYKIKPRH DSGIKAKISM KT

Genular Protein ID: 3737806720

Symbol: Q9HBL1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 199
  • Mass: 23511
  • Checksum: 5BC81339BC23DD9E
  • Sequence:
  • MSRAVTIAEA FCHILFRIIS EILMRMLGKE QCLFPLPEPR DLFQASQMKF EVFQKDLRKL 
    RKDLKACEVE AGKVYQVSSK EHMQPFKENM EQFIIQAKID QEAEENSLTE THKCFLETTA 
    YFFMKPKLGE KEVSPNAFFS IWHEFSSDFK DFWKKENKLL LQERVKEAEE VCRQKKGKSL 
    YKIKPRHDSG IKAKISMKT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.