Details for: Ascl3

Gene ID: 56787

Symbol: Ascl3

Ensembl ID: ENSMUSG00000035951

Description: achaete-scute family bHLH transcription factor 3

Associated with

  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Epithelium development
    (GO:0060429)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein dimerization activity
    (GO:0046983)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Salivary gland development
    (GO:0007431)
  • Sensory epithelium regeneration
    (GO:0070654)
  • Tissue homeostasis
    (GO:0001894)
  • Transcription regulator complex
    (GO:0005667)

Other Information

Genular Protein ID: 3738588562

Symbol: ASCL3_MOUSE

Name: Achaete-scute homolog 3

UniProtKB Accession Codes:

Q9JJR7 Q3SXE3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 1 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11784080

Title: Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice.

PubMed ID: 11784080

DOI: 10.1006/dbio.2001.0473

PubMed ID: 11528127

Title: Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7.

PubMed ID: 11528127

DOI: 10.1159/000056999

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18572159

Title: Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands.

PubMed ID: 18572159

DOI: 10.1016/j.ydbio.2008.04.018

PubMed ID: 21377457

Title: Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration.

PubMed ID: 21377457

DOI: 10.1016/j.ydbio.2011.02.025

PubMed ID: 27910949

Title: Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium.

PubMed ID: 27910949

DOI: 10.1038/srep38199

Sequence Information:

  • Length: 174
  • Mass: 20245
  • Checksum: D89E56C8A9D3440B
  • Sequence:
    • MDTRSYPSPP DRLSVFAESA HLPLSRPFYL DPMVTVHLCP ETPVPASYTD ELPLLPFSSD 
TLIMNNYGDP YPFPFPMPYT NYRRCDYTYG PAFIRKRNER ERQRVKCVNE GYARLRRHLP 
EDYLEKRLSK VETLRAAIKY ISYLQSLLYP DESETKKNPR TASCGSLDPA LRVI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.