Details for: Cacna2d2
Associated with
Other Information
Genular Protein ID: 3475973436
Symbol: CA2D2_MOUSE
Name: Voltage-dependent calcium channel subunit alpha-2/delta-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11130987
Title: Genomic organization of the mouse and human alpha2delta2 voltage-dependent calcium channel subunit genes.
PubMed ID: 11130987
PubMed ID: 11487633
Title: Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells.
PubMed ID: 11487633
PubMed ID: 14660671
Title: entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse.
PubMed ID: 14660671
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12465718
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
PubMed ID: 12465718
PubMed ID: 10766861
Title: Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2).
PubMed ID: 10766861
PubMed ID: 10762351
Title: Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit.
PubMed ID: 10762351
PubMed ID: 11306709
Title: Calcium channel alpha(2)delta subunits-structure and Gabapentin binding.
PubMed ID: 11306709
PubMed ID: 11756448
Title: The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function.
PubMed ID: 11756448
PubMed ID: 15331424
Title: Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene.
PubMed ID: 15331424
PubMed ID: 16061813
Title: The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of alpha2delta subunits is key to trafficking voltage-gated Ca2+ channels.
PubMed ID: 16061813
PubMed ID: 17052222
Title: Do voltage-gated calcium channel alpha2delta subunits require proteolytic processing into alpha2 and delta to be functional?
PubMed ID: 17052222
DOI: 10.1042/bst0340894
PubMed ID: 16928863
Title: The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.
PubMed ID: 16928863
PubMed ID: 17135419
Title: The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression.
PubMed ID: 17135419
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1154
- Mass: 130385
- Checksum: AE4F646D89A96053
- Sequence:
MAVPARTCGA SWPGPVRTAR PWPGRGPRPC PDPRGPASGP ARPLLLLLPP LLLLPLLTAP GASAYSFPQQ HTMQHWARRL EQEIDGVMRI FGGVQQLREI YKDNRNLFEV QENEPQKLVE KVAGDIESLL DRKVQALKRL ADAAENFQKA HRWQDNIKEE DIMYYDAKAD AELDDPESED MERGSKTSAL RLDFIEDPNF KNKVNYSYTA VQIPTDIYKG STVILNELNW TEALENVFIE NRRQDPTLLW QVFGSATGVT RYYPATPWRA PKKIDLYDVR RRPWYIQGAS SPKDMVIIVD VSGSVSGLTL KLMKTSVCEM LDTLSDDDYV NVASFNEKAQ PVSCFTHLVQ ANVRNKKVFK EAVQGMVAKG TTGYKAGFEY AFDQLQNSNI TRANCNKMIM MFTDGGEDRV QDVFEKYNWP NRTVRVFTFS VGQHNYDVTP LQWMACTNKG YYFEIPSIGA IRINTQEYLD VLGRPMVLAG KDAKQVQWTN VYEDALGLGL VVTGTLPVFN LTQDGPGEKK NQLILGVMGI DVALNDIKRL TPNYTLGANG YVFAIDLNGY VLLHPNLKPQ TTNFREPVTL DFLDAELEDE NKEEIRRSMI DGDKGHKQIR TLVKSLDERY IDEVIRNYTW VPIRSTNYSL GLVLPPYSTY YLQANLSDQI LQVKLPISKL KDFEFLLPSS FESEGHVFIA PREYCKDLNA SDNNTEFLKN FIELMEKVTP DSKQCNNFLL HNLILDTGIT QQLVERVWRD QDLNTYSLLA VFAATDGGIT RVFPNKAAED WTENPEPFNA SFYRRSLDNH GYIFKPPHQD SLLRPLELEN DTVGVLVSTA VELSLGRRTL RPAVVGVKLD LEAWAEKFKV LASNRTHQDQ PQKCGPSSHC EMDCEVNNED LLCVLIDDGG FLVLSNQNHQ WDQVGRFFSE VDANLMLALY NNSFYTRKES YDYQAACAPQ PPGNLGAAPR GVFVPTIADF LNLAWWTSAA AWSLFQQLLY GLIYHSWFQA DPAEAEGSPE TRESSCVMKQ TQYYFGSVNA SYNAIIDCGN CSRLFHAQRL TNTNLLFVVA EKPLCSQCEA GRLLQKETHS DGPEQCELVQ RPRYRRGPHI CFDYNATEDT SDCGRGASFP PSLGVLVSLQ LLLLLGLPPR PQPQVHSFAA SRHL
Genular Protein ID: 3381608319
Symbol: A0A411ACZ2_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 30683685
Title: Presynaptic alpha2delta-2 calcium channel subunits regulate postsynaptic GABAA-receptor abundance and axonal wiring.
PubMed ID: 30683685
Sequence Information:
- Length: 1147
- Mass: 129653
- Checksum: 9DEBB0CE22DCD170
- Sequence:
MAVPARTCGA SWPGPVRTAR PWPGRGPRPC PDPRGPASGP ARPLLLLLPP LLLLPLLTAP GASAYSFPQQ HTMQHWARRL EQEIDGVMRI FGGVQQLREI YKDNRNLFEV QENEPQKLVE KVAGDIESLL DRKVQALKRL ADAAENFQKA HRWQDNIKEE DIMYYDAKAD AELDDPESED MERGSKTSAL RLDFIEDPNF KNKVNYSYTA VQIPTDIYKG STVILNELNW TEALENVFIE NRRQDPTLLW QVFGSATGVT RYYPATPWRA PKKIDLYDVR RRPWYIQGAS SPKDMVIIVD VSGSVSGLTL KLMKTSVCEM LDTLSDDDYV NVASFNEKAQ PVSCFTHLVQ ANVRNKKVFK EAVQGMVAKG TTGYKAGFEY AFDQLQNSNI TRANCNKMIM MFTDGGEDRV QDVFEKYNWP NRTVRVFTFS VGQHNYDVTP LQWMACTNKG YYFEIPSIGA IRINTQEYLD VLGRPMVLAG KDAKQVQWTN VYEDALGLGL VVTGTLPVFN LTQDGPGEKK NQLILGVMGI DVALNDIKRL TPNYTLGANG YVFAIDLNGY VLLHPNLKPQ TTNFREPVTL DFLDAELEDE NKEEIRRSMI DGDKGHKQIR TLVKSLDERY IDEVIRNYTW VPIRSTNYSL GLVLPPYSTY YLQANLSDQI LQVKYFEFLL PSSFESEGHV FIAPREYCKD LNASDNNTEF LKNFIELMEK VTPDSKQCNN FLLHNLILDT GITQQLVERV WRDQDLNTYS LLAVFAATDG GITRVFPNKA AEDWTENPEP FNASFYRRSL DNHGYIFKPP HQDSLLRPLE LENDTVGVLV STAVELSLGR RTLRPAVVGV KLDLEAWAEK FKVLASNRTH QDQPQKCGPS SHCEMDCEVN NEDLLCVLID DGGFLVLSNQ NHQWDQVGRF FSEVDANLML ALYNNSFYTR KESYDYQAAC APQPPGNLGA APRGVFVPTI ADFLNLAWWT SAAAWSLFQQ LLYGLIYHSW FQADPAEAEG SPETRESSCV MKQTQYYFGS VNASYNAIID CGNCSRLFHA QRLTNTNLLF VVAEKPLCSQ CEAGRLLQKE THSDGPEQCE LVQRPRYRRG PHICFDYNAT EDTSDCGRGA SFPPSLGVLV SLQLLLLLGL PPRPQPQVHS FAASRHL
Genular Protein ID: 2892890177
Symbol: A0A411ACW5_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 30683685
Title: Presynaptic alpha2delta-2 calcium channel subunits regulate postsynaptic GABAA-receptor abundance and axonal wiring.
PubMed ID: 30683685
Sequence Information:
- Length: 1150
- Mass: 129965
- Checksum: CC37C76BB5CE5EB9
- Sequence:
MAVPARTCGA SWPGPVRTAR PWPGRGPRPC PDPRGPASGP ARPLLLLLPP LLLLPLLTAP GASAYSFPQQ HTMQHWARRL EQEIDGVMRI FGGVQQLREI YKDNRNLFEV QENEPQKLVE KVAGDIESLL DRKVQALKRL ADAAENFQKA HRWQDNIKEE DIMYYDAKAD AELDDPESED MERGSKTSAL RLDFIEDPNF KNKVNYSYTA VQIPTDIYKG STVILNELNW TEALENVFIE NRRQDPTLLW QVFGSATGVT RYYPATPWRA PKKIDLYDVR RRPWYIQGAS SPKDMVIIVD VSGSVSGLTL KLMKTSVCEM LDTLSDDDYV NVASFNEKAQ PVSCFTHLVQ ANVRNKKVFK EAVQGMVAKG TTGYKAGFEY AFDQLQNSNI TRANCNKMIM MFTDGGEDRV QDVFEKYNWP NRTVRVFTFS VGQHNYDVTP LQWMACTNKG YYFEIPSIGA IRINTQEYLD VLGRPMVLAG KDAKQVQWTN VYEDALGLGL VVTGTLPVFN LTQDGPGEKK NQLILGVMGI DVALNDIKRL TPNYTLGANG YVFAIDLNGY VLLHPNLKPQ TTNFREPVTL DFLDAELEDE NKEEIRRSMI DGDKGHKQIR TLVKSLDERY IDEVIRNYTW VPIRSTNYSL GLVLPPYSTY YLQANLSDQI LQVKYFEFLL PSSFESEGHV FIAPREYCKD LNASDNNTEF LKNFIELMEK VTPDSKQCNN FLLHNLILDT GITQQLVERV WRDQDLNTYS LLAVFAATDG GITRVFPNKA AEDWTENPEP FNASFYRRSL DNHGYIFKPP HQDSLLRPLE LENDTVGVLV STAVELSLGR RTLRPAVVGV KLDLEAWAEK FKVLASNRTH QDQPQKQCGP SSHCEMDCEV NNEDLLCVLI DDGGFLVLSN QNHQWDQVGR FFSEVDANLM LALYNNSFYT RKESYDYQAA CAPQPPGNLG AAPRGVFVPT IADFLNLAWW TSAAAWSLFQ QLLYGLIYHS WFQADPAEAE GSPETRESSC VMKQTQYYFG SVNASYNAII DCGNCSRLFH AQRLTNTNLL FVVAEKPLCS QCEAGRLLQK ETHCPADGPE QCELVQRPRY RRGPHICFDY NATEDTSDCG RGASFPPSLG VLVSLQLLLL LGLPPRPQPQ VHSFAASRHL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.