Pth1r | ENSRNOG00000020948 | NCBI 56813

Details for: Pth1r

Gene ID: 56813

Symbol: Pth1r

Ensembl ID: ENSRNOG00000020948

Description: parathyroid hormone 1 receptor

Associated with

Class b/2 (secretin family receptors)
(R-RNO-373080)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Apical plasma membrane
(GO:0016324)
Basolateral plasma membrane
(GO:0016323)
Bone mineralization
(GO:0030282)
Bone resorption
(GO:0045453)
Brush border membrane
(GO:0031526)
Cell maturation
(GO:0048469)
Cell population proliferation
(GO:0008283)
Cell surface receptor signaling pathway
(GO:0007166)
Chondrocyte differentiation
(GO:0002062)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor signaling pathway
(GO:0007186)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
Intracellular calcium ion homeostasis
(GO:0006874)
In utero embryonic development
(GO:0001701)
Negative regulation of cell population proliferation
(GO:0008285)
Ossification
(GO:0001503)
Osteoblast development
(GO:0002076)
Parathyroid hormone receptor activity
(GO:0004991)
Peptide hormone binding
(GO:0017046)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of inositol phosphate biosynthetic process
(GO:0060732)
Protein homodimerization activity
(GO:0042803)
Protein self-association
(GO:0043621)
Receptor complex
(GO:0043235)
Skeletal system development
(GO:0001501)

Other Information

Proteins

Parathyroid hormone/parathyroid hormone-related peptide receptor

Genular Protein ID: 1117340569

Symbol: PTH1R_RAT

Name: Parathyroid hormone/parathyroid hormone-related peptide receptor

UniProtKB Accession Codes:

P25961

Database IDs:

Citations:

PubMed ID: 1313566

Title: Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

PubMed ID: 1313566

DOI: 10.1073/pnas.89.7.2732

PubMed ID: 8020952

Title: Cloning of a parathyroid hormone/parathyroid hormone-related peptide receptor (PTHR) cDNA from a rat osteosarcoma (UMR 106) cell line: chromosomal assignment of the gene in the human, mouse, and rat genomes.

PubMed ID: 8020952

DOI: 10.1006/geno.1994.1122

Sequence Information:

Length: 591
Mass: 66261
Checksum: 21944F3051B9E9C1
Sequence:

MGAARIAPSL ALLLCCPVLS SAYALVDADD VFTKEEQIFL LHRAQAQCDK LLKEVLHTAA 
NIMESDKGWT PASTSGKPRK EKASGKFYPE SKENKDVPTG SRRRGRPCLP EWDNIVCWPL 
GAPGEVVAVP CPDYIYDFNH KGHAYRRCDR NGSWEVVPGH NRTWANYSEC LKFMTNETRE 
REVFDRLGMI YTVGYSMSLA SLTVAVLILA YFRRLHCTRN YIHMHMFLSF MLRAASIFVK 
DAVLYSGFTL DEAERLTEEE LHIIAQVPPP PAAAAVGYAG CRVAVTFFLY FLATNYYWIL 
VEGLYLHSLI FMAFFSEKKY LWGFTIFGWG LPAVFVAVWV GVRATLANTG CWDLSSGHKK 
WIIQVPILAS VVLNFILFIN IIRVLATKLR ETNAGRCDTR QQYRKLLRST LVLVPLFGVH 
YTVFMALPYT EVSGTLWQIQ MHYEMLFNSF QGFFVAIIYC FCNGEVQAEI RKSWSRWTLA 
LDFKRKARSG SSSYSYGPMV SHTSVTNVGP RAGLSLPLSP RLPPATTNGH SQLPGHAKPG 
APATETETLP VTMAVPKDDG FLNGSCSGLD EEASGSARPP PLLQEEWETV M

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.