Details for: Lgi1

Gene ID: 56839

Symbol: Lgi1

Ensembl ID: ENSMUSG00000067242

Description: leucine-rich repeat LGI family, member 1

Associated with

Other Information

Genular Protein ID: 1933360145

Symbol: LGI1_MOUSE

Name: Leucine-rich glioma-inactivated protein 1

UniProtKB Accession Codes:

Q9JIA1 A0A0G2JFT0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 14 Gene3D 1 GeneTree 1 Genevisible 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MGI 2 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10920229

Title: Identification of the promoter, genomic structure, and mouse ortholog of LGI1.

PubMed ID: 10920229

DOI: 10.1007/s0033500101280

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15857855

Title: ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsy.

PubMed ID: 15857855

DOI: 10.1093/hmg/ddi169

PubMed ID: 16787412

Title: The LGI1/epitempin gene encodes two protein isoforms differentially expressed in human brain.

PubMed ID: 16787412

DOI: 10.1111/j.1471-4159.2006.03939.x

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 18974846

Title: LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11.

PubMed ID: 18974846

DOI: 10.7150/ijbs.4.387

PubMed ID: 19833108

Title: Regional distribution of the leucine-rich glioma inactivated (LGI) gene family transcripts in the adult mouse brain.

PubMed ID: 19833108

DOI: 10.1016/j.brainres.2009.10.013

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26269648

Title: Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing.

PubMed ID: 26269648

DOI: 10.1523/jneurosci.1346-15.2015

Sequence Information:

  • Length: 557
  • Mass: 63644
  • Checksum: 2692D53F13DEC431
  • Sequence:
    • MESESSRRMG NACIPLKRIA YFLCLFSVVL LTEGKKPAKP KCPAVCTCSK DNALCENARS 
IPRTVPPDVI SLSFVRSGFT EISEGSFLFT PSLQLLLFTS NSFDVISDDA FIGLPHLEYL 
FIENNNIKSI SRHTFRGLKS LIHLSLANNN LQTLPKDIFK GLDSLTNVDL RGNAFNCDCK 
LKWLVEWLGH TNATVEDIYC EGPPEYKKRK INSLSPKDFD CIITEFAKSQ DLPYQSLSID 
TFSYLNDEYV VIAQPFTGKC IFLEWDHVEK TFRNYDNITG TSTVVCKPIV IDTQLYVIVA 
QLFGGSHIYK RDGFANKFIK IQDIEVLKIR KPNDIETFKI EDNWYFVVAD SSKAGFTTIY 
KWNGNGFYSH QSLHAWYRDT DVEYLEIARP PLALRTPHLI LSSSSQRPVI YQWSKATQLF 
TNQTDIPNME DVYAVKHFSV KGDVYICLTR FIGDSKVMKW GGSSFQDIQR MPSRGSMVFQ 
PLQINNYQYA ILGSDYSFTQ VYNWDAEKAK FVKFQELNVQ APRSFTHVSI NKRNFLFASS 
FKGNTQIYKH VIVDLSA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.