Details for: Trpm5

Gene ID: 56843

Symbol: Trpm5

Ensembl ID: ENSMUSG00000009246

Description: transient receptor potential cation channel, subfamily M, member 5

Associated with

Other Information

Genular Protein ID: 836228138

Symbol: TRPM5_MOUSE

Name: Transient receptor potential cation channel subfamily M member 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10907850

Title: Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human.

PubMed ID: 10907850

DOI: 10.1093/dnares/7.3.195

PubMed ID: 10903843

Title: Mtr1, a novel biallelically expressed gene in the center of the mouse distal chromosome 7 imprinting cluster, is a member of the Trp gene family.

PubMed ID: 10903843

DOI: 10.1006/geno.2000.6234

PubMed ID: 10915772

Title: Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.

PubMed ID: 10915772

DOI: 10.1093/hmg/9.12.1829

PubMed ID: 12842017

Title: TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel.

PubMed ID: 12842017

DOI: 10.1016/s0960-9822(03)00431-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 12368808

Title: A transient receptor potential channel expressed in taste receptor cells.

PubMed ID: 12368808

DOI: 10.1038/nn952

PubMed ID: 14657398

Title: Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5.

PubMed ID: 14657398

DOI: 10.1073/pnas.2334159100

PubMed ID: 15670874

Title: Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.

PubMed ID: 15670874

DOI: 10.1016/j.ceca.2004.11.001

PubMed ID: 15731110

Title: Extracellular acid block and acid-enhanced inactivation of the Ca2+-activated cation channel TRPM5 involve residues in the S3-S4 and S5-S6 extracellular domains.

PubMed ID: 15731110

DOI: 10.1074/jbc.m414072200

PubMed ID: 16355226

Title: Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.

PubMed ID: 16355226

DOI: 10.1038/nature04248

PubMed ID: 16935556

Title: Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells.

PubMed ID: 16935556

DOI: 10.1016/j.bbalip.2006.07.005

PubMed ID: 16436689

Title: Trpm5 null mice respond to bitter, sweet, and umami compounds.

PubMed ID: 16436689

DOI: 10.1093/chemse/bjj027

PubMed ID: 17610722

Title: TRPM5, a taste-signaling transient receptor potential ion-channel, is a ubiquitous signaling component in chemosensory cells.

PubMed ID: 17610722

DOI: 10.1186/1471-2202-8-49

PubMed ID: 17522321

Title: The transduction channel TRPM5 is gated by intracellular calcium in taste cells.

PubMed ID: 17522321

DOI: 10.1523/jneurosci.4973-06.2007

PubMed ID: 17267604

Title: Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals.

PubMed ID: 17267604

DOI: 10.1073/pnas.0610201104

Sequence Information:

  • Length: 1158
  • Mass: 130844
  • Checksum: F0A5237EC67867CE
  • Sequence:
  • MQTTQSSCPG SPPDTEDGWE PILCRGEINF GGSGKKRGKF VKVPSSVAPS VLFELLLTEW 
    HLPAPNLVVS LVGEERPLAM KSWLRDVLRK GLVKAAQSTG AWILTSALHV GLARHVGQAV 
    RDHSLASTST KIRVVAIGMA SLDRILHRQL LDGVHQKEDT PIHYPADEGN IQGPLCPLDS 
    NLSHFILVES GALGSGNDGL TELQLSLEKH ISQQRTGYGG TSCIQIPVLC LLVNGDPNTL 
    ERISRAVEQA APWLILAGSG GIADVLAALV SQPHLLVPQV AEKQFREKFP SECFSWEAIV 
    HWTELLQNIA AHPHLLTVYD FEQEGSEDLD TVILKALVKA CKSHSQEAQD YLDELKLAVA 
    WDRVDIAKSE IFNGDVEWKS CDLEEVMTDA LVSNKPDFVR LFVDSGADMA EFLTYGRLQQ 
    LYHSVSPKSL LFELLQRKHE EGRLTLAGLG AQQARELPIG LPAFSLHEVS RVLKDFLHDA 
    CRGFYQDGRR MEERGPPKRP AGQKWLPDLS RKSEDPWRDL FLWAVLQNRY EMATYFWAMG 
    REGVAAALAA CKIIKEMSHL EKEAEVARTM REAKYEQLAL DLFSECYGNS EDRAFALLVR 
    RNHSWSRTTC LHLATEADAK AFFAHDGVQA FLTKIWWGDM ATGTPILRLL GAFTCPALIY 
    TNLISFSEDA PQRMDLEDLQ EPDSLDMEKS FLCSRGGQLE KLTEAPRAPG DLGPQAAFLL 
    TRWRKFWGAP VTVFLGNVVM YFAFLFLFTY VLLVDFRPPP QGPSGSEVTL YFWVFTLVLE 
    EIRQGFFTDE DTHLVKKFTL YVEDNWNKCD MVAIFLFIVG VTCRMVPSVF EAGRTVLAID 
    FMVFTLRLIH IFAIHKQLGP KIIIVERMMK DVFFFLFFLS VWLVAYGVTT QALLHPHDGR 
    LEWIFRRVLY RPYLQIFGQI PLDEIDEARV NCSLHPLLLE SSASCPNLYA NWLVILLLVT 
    FLLVTNVLLM NLLIAMFSYT FQVVQGNADM FWKFQRYHLI VEYHGRPALA PPFILLSHLS 
    LVLKQVFRKE AQHKRQHLER DLPDPLDQKI ITWETVQKEN FLSTMEKRRR DSEGEVLRKT 
    AHRVDLIAKY IGGLREQEKR IKCLESQANY CMLLLSSMTD TLAPGGTYSS SQNCGCRSQP 
    ASARDREYLE SGLPPSDT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.