Details for: TCIM

Gene ID: 56892

Symbol: TCIM

Ensembl ID: ENSG00000176907

Description: transcriptional and immune response regulator

Associated with

Other Information

Genular Protein ID: 3454527523

Symbol: TCIM_HUMAN

Name: Thyroid cancer protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11056052

Title: Cloning of TC-1 (C8orf4), a novel gene found to be overexpressed in thyroid cancer.

PubMed ID: 11056052

DOI: 10.1006/geno.2000.6348

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15087392

Title: TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer.

PubMed ID: 15087392

DOI: 10.1158/0008-5472.can-03-2093

PubMed ID: 16424001

Title: TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby.

PubMed ID: 16424001

DOI: 10.1158/0008-5472.can-05-3124

PubMed ID: 16730711

Title: TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells.

PubMed ID: 16730711

DOI: 10.1016/j.febslet.2006.05.036

PubMed ID: 17603013

Title: TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response.

PubMed ID: 17603013

DOI: 10.1016/j.bbrc.2007.06.077

PubMed ID: 18959821

Title: TC1 (C8orf4) is involved in ERK1/2 pathway-regulated G(1)- to S-phase transition.

PubMed ID: 18959821

DOI: 10.5483/bmbrep.2008.41.10.733

PubMed ID: 19684084

Title: TC1(C8orf4) is a novel endothelial inflammatory regulator enhancing NF-kappaB activity.

PubMed ID: 19684084

DOI: 10.4049/jimmunol.0900956

PubMed ID: 24941347

Title: TC-1 overexpression promotes cell proliferation in human non-small cell lung cancer that can be inhibited by PD173074.

PubMed ID: 24941347

DOI: 10.1371/journal.pone.0100075

PubMed ID: 25985737

Title: C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.

PubMed ID: 25985737

DOI: 10.1038/ncomms8122

Sequence Information:

  • Length: 106
  • Mass: 12337
  • Checksum: 2D5C93B7E1E7AE09
  • Sequence:
  • MKAKRSHQAV IMSTSLRVSP SIHGYHFDTA SRKKAVGNIF ENTDQESLER LFRNSGDKKA 
    EERAKIIFAI DQDVEEKTRA LMALKKRTKD KLFQFLKLRK YSIKVH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.