Details for: UBQLN4

Gene ID: 56893

Symbol: UBQLN4

Ensembl ID: ENSG00000160803

Description: ubiquilin 4

Associated with

Other Information

Genular Protein ID: 222582144

Symbol: UBQL4_HUMAN

Name: Ataxin-1 ubiquitin-like-interacting protein A1U

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11001934

Title: Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein.

PubMed ID: 11001934

DOI: 10.1093/oxfordjournals.hmg.a018922

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10575211

Title: Identification of two paralogous regions mapping to the short and long arms of human chromosome 2 comprising LIS1 pseudogenes.

PubMed ID: 10575211

DOI: 10.1159/000015344

PubMed ID: 15280365

Title: The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up.

PubMed ID: 15280365

DOI: 10.1074/jbc.m406284200

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18307982

Title: Herp enhances ER-associated protein degradation by recruiting ubiquilins.

PubMed ID: 18307982

DOI: 10.1016/j.bbrc.2008.02.086

PubMed ID: 20702650

Title: Mumps virus small hydrophobic protein targets ataxin-1 ubiquitin-like interacting protein (ubiquilin 4).

PubMed ID: 20702650

DOI: 10.1099/vir.0.024638-0

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23459205

Title: Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery.

PubMed ID: 23459205

DOI: 10.1038/embor.2013.22

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24674348

Title: The ubiquilin gene family: evolutionary patterns and functional insights.

PubMed ID: 24674348

DOI: 10.1186/1471-2148-14-63

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27113755

Title: UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation.

PubMed ID: 27113755

DOI: 10.15252/embr.201541402

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28463112

Title: A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis.

PubMed ID: 28463112

DOI: 10.7554/elife.25453

PubMed ID: 29666234

Title: Nuclear export of ubiquitinated proteins via the UBIN-POST system.

PubMed ID: 29666234

DOI: 10.1073/pnas.1711017115

PubMed ID: 30612738

Title: UBQLN4 represses homologous recombination and is overexpressed in aggressive tumors.

PubMed ID: 30612738

DOI: 10.1016/j.cell.2018.11.024

PubMed ID: 34245648

Title: UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

PubMed ID: 34245648

DOI: 10.1002/1878-0261.13058

Sequence Information:

  • Length: 601
  • Mass: 63853
  • Checksum: E57B9FFEF90793FE
  • Sequence:
  • MAEPSGAETR PPIRVTVKTP KDKEEIVICD RASVKEFKEE ISRRFKAQQD QLVLIFAGKI 
    LKDGDTLNQH GIKDGLTVHL VIKTPQKAQD PAAATASSPS TPDPASAPST TPASPATPAQ 
    PSTSGSASSD AGSGSRRSSG GGPSPGAGEG SPSATASILS GFGGILGLGS LGLGSANFME 
    LQQQMQRQLM SNPEMLSQIM ENPLVQDMMS NPDLMRHMIM ANPQMQQLME RNPEISHMLN 
    NPELMRQTME LARNPAMMQE MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMFSAAREQ 
    FGNNPFSSLA GNSDSSSSQP LRTENREPLP NPWSPSPPTS QAPGSGGEGT GGSGTSQVHP 
    TVSNPFGINA ASLGSGMFNS PEMQALLQQI SENPQLMQNV ISAPYMRSMM QTLAQNPDFA 
    AQMMVNVPLF AGNPQLQEQL RLQLPVFLQQ MQNPESLSIL TNPRAMQALL QIQQGLQTLQ 
    TEAPGLVPSL GSFGISRTPA PSAGSNAGST PEAPTSSPAT PATSSPTGAS SAQQQLMQQM 
    IQLLAGSGNS QVQTPEVRFQ QQLEQLNSMG FINREANLQA LIATGGDINA AIERLLGSQL 
    S

Genular Protein ID: 3569045768

Symbol: Q59F94_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 600
  • Mass: 63740
  • Checksum: DFBA259E8A40BACD
  • Sequence:
  • AEPSGAETRP PIRVTVKTPK DKEEIVICDR ASVKEFKEEI SRRFKAQQDQ LVLIFAGKIL 
    KDGDTLNQHG IKDGLTVHLV IKTPQKAQDP AAATASSPST PDPASAPSTT PASPATPAQP 
    STSGSASSDA GSGSRRSSGG GPSPGAGEGS PSATASILSG FGGILGLGSL GLGSANFMEL 
    QQQMQRQLMS NPEMLSQIME NPLVQDMMSN PDLMRHMIMA NPQMQQLMER NPEISHMLNN 
    PELMRQTMEL ARNPAMMQEM MRNQDRALSN LESIPGGYNA LRRMYTDIQE PMFSAAREQF 
    GNNPFSSLAG NSDSSSSQPL RTENREPLPN PWSPSPPTSQ APGSGGEGTG GSGTSQVHPT 
    VSNPFGINAA SLGSGMFNSP EMQALLQQIS ENPQLMQNVI SAPYMRSMMQ TLAQNPDFAA 
    QMMVNVPLFA GNPQLQEQLR LQLPVFLQQM QNPESLSILT NPRAMQALLQ IQQGLQTLQT 
    EAPGLVPSLG SFGMSRTPAP SAGSNAGSTP EAPTSSPATP ATSSPTGASS AQQQLMQQMI 
    QLLAGSGNSQ VQTPEVRFQQ QLEQLNSMGF INREANLQAL IATGGDINAA IERLLGSQLS

Genular Protein ID: 2796000473

Symbol: B4DZF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 581
  • Mass: 62185
  • Checksum: A786637F8276CD26
  • Sequence:
  • MAEPSGAETR PPIRVTVKTP KDKEEIVICD RASVKEFKEE ISRRFKAQQD QLVLIFAGKI 
    LKDGDTLNQH GIKDGLTVHL VIKTPQKAQD PAAATASSPS TPDPASAPST TPASPATPAQ 
    PSTSGSASSD AGSGSRRSSA GFGGILGLGS LGLGSANFME LQQQMQRQLM SNPEMLSQIM 
    ENPLVQDMMS NPDLMRHMIM ANPQMQQLME RNPEISHMLN NPELMRQTME LARNPAMMQE 
    MMRNQDRALS NLESIPGGYN ALRRMYTDIQ EPMFSAAREQ FGNNPFSSLA GNSDSSSSQP 
    LRTENREPLP NPWSPSPPTS QAPGSGGEGT GGSGTSQVHP TVSNPFGINA ASLGSGMFNS 
    PEMQALLQQI SENPQLMQNV ISAPYMRSMM QTLAQNPDFA AQMMVNVPLF AGNPQLQEQL 
    RLQLPVFLQQ MQNPESLSIL TNPRAMQALL QIQQGLQTLQ TEAPGLVPSL GSFGISRTPA 
    PSAGSNAGST PEAPTSSPAT PATSSPTGAS SAQQQLMQQM IQLLAGSGNS QVQTPEVRFQ 
    QQLEQLNSMG FINREANLQA LIATGGDINA AIERLLGSQL S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.