XAB2 | ENSG00000076924 | NCBI 56949

Details for: XAB2

Gene ID: 56949

Symbol: XAB2

Ensembl ID: ENSG00000076924

Description: XPA binding protein 2

Associated with

Dna repair
(R-HSA-73894)
Dual incision in tc-ner
(R-HSA-6782135)
Formation of tc-ner pre-incision complex
(R-HSA-6781823)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-HSA-6782210)
Metabolism of rna
(R-HSA-8953854)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Nucleotide excision repair
(R-HSA-5696398)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-HSA-6781827)
Blastocyst development
(GO:0001824)
Catalytic step 2 spliceosome
(GO:0071013)
Dna-templated transcription
(GO:0006351)
Generation of catalytic spliceosome for first transesterification step
(GO:0000349)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Mrna splicing, via spliceosome
(GO:0000398)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Post-mrna release spliceosomal complex
(GO:0071014)
Protein binding
(GO:0005515)
Prp19 complex
(GO:0000974)
Transcription-coupled nucleotide-excision repair
(GO:0006283)
U2-type catalytic step 2 spliceosome
(GO:0071007)

Other Information

Proteins

Pre-mRNA-splicing factor SYF1

Genular Protein ID: 2189339915

Symbol: SYF1_HUMAN

Name: Pre-mRNA-splicing factor SYF1

UniProtKB Accession Codes:

Q9HCS7 Q8TET6 Q96HB0 Q96IW0 Q9NRG6 Q9ULP3

Database IDs:

Citations:

PubMed ID: 10944529

Title: XAB2, a novel tetratricopeptide repeat protein, involved in transcription-coupled DNA repair and transcription.

PubMed ID: 10944529

DOI: 10.1074/jbc.m004936200

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10574461

Title: Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

PubMed ID: 10574461

DOI: 10.1093/dnares/6.5.329

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 17981804

Title: Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair.

PubMed ID: 17981804

DOI: 10.1074/jbc.m706647200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25599396

Title: The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes.

PubMed ID: 25599396

DOI: 10.1038/nsmb.2951

PubMed ID: 28502770

Title: An Atomic Structure of the Human Spliceosome.

PubMed ID: 28502770

DOI: 10.1016/j.cell.2017.04.033

PubMed ID: 28076346

Title: Cryo-EM structure of a human spliceosome activated for step 2 of splicing.

PubMed ID: 28076346

DOI: 10.1038/nature21079

Sequence Information:

Length: 855
Mass: 100010
Checksum: CF766917CD65F6FD
Sequence:

MVVMARLSRP ERPDLVFEEE DLPYEEEIMR NQFSVKCWLR YIEFKQGAPK PRLNQLYERA 
LKLLPCSYKL WYRYLKARRA QVKHRCVTDP AYEDVNNCHE RAFVFMHKMP RLWLDYCQFL 
MDQGRVTHTR RTFDRALRAL PITQHSRIWP LYLRFLRSHP LPETAVRGYR RFLKLSPESA 
EEYIEYLKSS DRLDEAAQRL ATVVNDERFV SKAGKSNYQL WHELCDLISQ NPDKVQSLNV 
DAIIRGGLTR FTDQLGKLWC SLADYYIRSG HFEKARDVYE EAIRTVMTVR DFTQVFDSYA 
QFEESMIAAK METASELGRE EEDDVDLELR LARFEQLISR RPLLLNSVLL RQNPHHVHEW 
HKRVALHQGR PREIINTYTE AVQTVDPFKA TGKPHTLWVA FAKFYEDNGQ LDDARVILEK 
ATKVNFKQVD DLASVWCQCG ELELRHENYD EALRLLRKAT ALPARRAEYF DGSEPVQNRV 
YKSLKVWSML ADLEESLGTF QSTKAVYDRI LDLRIATPQI VINYAMFLEE HKYFEESFKA 
YERGISLFKW PNVSDIWSTY LTKFIARYGG RKLERARDLF EQALDGCPPK YAKTLYLLYA 
QLEEEWGLAR HAMAVYERAT RAVEPAQQYD MFNIYIKRAA EIYGVTHTRG IYQKAIEVLS 
DEHAREMCLR FADMECKLGE IDRARAIYSF CSQICDPRTT GAFWQTWKDF EVRHGNEDTI 
KEMLRIRRSV QATYNTQVNF MASQMLKVSG SATGTVSDLA PGQSGMDDMK LLEQRAEQLA 
AEAERDQPLR AQSKILFVRS DASREELAEL AQQVNPEEIQ LGEDEDEDEM DLEPNEVRLE 
QQSVPAAVFG SLKED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: XAB2

Associated with

Other Information

XAB2, a novel tetratricopeptide repeat protein, involved in transcription-coupled DNA repair and transcription. PubMed ID: 10944529

Large-scale cDNA transfection screening for genes related to cancer development and progression. PubMed ID: 15498874

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. PubMed ID: 10574461

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. PubMed ID: 11991638

Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. PubMed ID: 17981804

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. PubMed ID: 25599396

An Atomic Structure of the Human Spliceosome. PubMed ID: 28502770

Cryo-EM structure of a human spliceosome activated for step 2 of splicing. PubMed ID: 28076346