BAAT | ENSG00000136881 | NCBI 570

Details for: BAAT

Gene ID: 570

Symbol: BAAT

Ensembl ID: ENSG00000136881

Description: bile acid-CoA:amino acid N-acyltransferase

Associated with

Bile acid and bile salt metabolism
(R-HSA-194068)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Metabolism of steroids
(R-HSA-8957322)
Peroxisomal protein import
(R-HSA-9033241)
Protein localization
(R-HSA-9609507)
Recycling of bile acids and salts
(R-HSA-159418)
Synthesis of bile acids and bile salts
(R-HSA-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-HSA-193368)
Acyl-coa metabolic process
(GO:0006637)
Acyltransferase activity
(GO:0016746)
Animal organ regeneration
(GO:0031100)
Bile acid biosynthetic process
(GO:0006699)
Bile acid conjugation
(GO:0002152)
Bile acid metabolic process
(GO:0008206)
Carboxylic ester hydrolase activity
(GO:0052689)
Choloyl-coa hydrolase activity
(GO:0033882)
Cytosol
(GO:0005829)
Fatty acid metabolic process
(GO:0006631)
Fatty acyl-coa hydrolase activity
(GO:0047617)
Glycine metabolic process
(GO:0006544)
Glycine n-choloyltransferase activity
(GO:0047963)
Intracellular membrane-bounded organelle
(GO:0043231)
Liver development
(GO:0001889)
Long-chain fatty acyl-coa hydrolase activity
(GO:0052816)
Medium-chain fatty acyl-coa hydrolase activity
(GO:0052815)
N-acyltransferase activity
(GO:0016410)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Protein binding
(GO:0005515)
Taurine metabolic process
(GO:0019530)
Very long-chain fatty acyl-coa hydrolase activity
(GO:0052817)

Other Information

Proteins

Choloyl-CoA hydrolase

Genular Protein ID: 2155909131

Symbol: BAAT_HUMAN

Name: Choloyl-CoA hydrolase

UniProtKB Accession Codes:

Q14032 Q3B7W9 Q96L31

Database IDs:

Citations:

PubMed ID: 8034703

Title: Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.

PubMed ID: 8034703

DOI: 10.1016/s0021-9258(17)32178-6

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2037576

Title: Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver.

PubMed ID: 2037576

DOI: 10.1016/s0021-9258(18)99213-6

PubMed ID: 12239217

Title: Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.

PubMed ID: 12239217

DOI: 10.1074/jbc.m207463200

PubMed ID: 12810727

Title: The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.

PubMed ID: 12810727

DOI: 10.1074/jbc.m300987200

PubMed ID: 23415802

Title: Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency.

PubMed ID: 23415802

DOI: 10.1053/j.gastro.2013.02.004

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12704386

Title: Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT.

PubMed ID: 12704386

DOI: 10.1038/ng1147

Sequence Information:

Length: 418
Mass: 46299
Checksum: 4B290BAEE97F23B3
Sequence:

MIQLTATPVS ALVDEPVHIR ATGLIPFQMV SFQASLEDEN GDMFYSQAHY RANEFGEVDL 
NHASSLGGDY MGVHPMGLFW SLKPEKLLTR LLKRDVMNRP FQVQVKLYDL ELIVNNKVAS 
APKASLTLER WYVAPGVTRI KVREGRLRGA LFLPPGEGLF PGVIDLFGGL GGLLEFRASL 
LASRGFASLA LAYHNYEDLP RKPEVTDLEY FEEAANFLLR HPKVFGSGVG VVSVCQGVQI 
GLSMAIYLKQ VTATVLINGT NFPFGIPQVY HGQIHQPLPH SAQLISTNAL GLLELYRTFE 
TTQVGASQYL FPIEEAQGQF LFIVGEGDKT INSKAHAEQA IGQLKRHGKN NWTLLSYPGA 
GHLIEPPYSP LCCASTTHDL RLHWGGEVIP HAAAQEHAWK EIQRFLRKHL IPDVTSQL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: BAAT

Associated with

Other Information

Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. PubMed ID: 8034703

DNA sequence and analysis of human chromosome 9. PubMed ID: 15164053

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver. PubMed ID: 2037576

Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase. PubMed ID: 12239217

The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine. PubMed ID: 12810727

Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. PubMed ID: 23415802

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. PubMed ID: 12704386