Details for: ACKR3
Associated with
Other Information
Genular Protein ID: 274480374
Symbol: ACKR3_HUMAN
Name: C-X-C chemokine receptor type 7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1675791
Title: Cloning and expression of the human vasoactive intestinal peptide receptor.
PubMed ID: 1675791
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1315461
PubMed ID: 16107333
Title: The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.
PubMed ID: 16107333
PubMed ID: 16940167
Title: A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.
PubMed ID: 16940167
DOI: 10.1084/jem.20052144
PubMed ID: 16455976
Title: Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells.
PubMed ID: 16455976
PubMed ID: 17804806
Title: Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.
PubMed ID: 17804806
PubMed ID: 18653785
Title: A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
PubMed ID: 18653785
DOI: 10.1189/jlb.0208088
PubMed ID: 19380869
Title: CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.
PubMed ID: 19380869
PubMed ID: 19641136
Title: Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands.
PubMed ID: 19641136
PubMed ID: 19255243
Title: AMD3100 is a CXCR7 ligand with allosteric agonist properties.
PubMed ID: 19255243
PubMed ID: 20388803
Title: The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
PubMed ID: 20388803
PubMed ID: 20373092
Title: Chemokine decoy receptors: structure-function and biological properties.
PubMed ID: 20373092
DOI: 10.1007/82_2010_19
PubMed ID: 20887389
Title: CXCR7: a new SDF-1-binding receptor in contrast to normal CD34(+) progenitors is functional and is expressed at higher level in human malignant hematopoietic cells.
PubMed ID: 20887389
PubMed ID: 20161793
Title: CXCR7 functions as a scavenger for CXCL12 and CXCL11.
PubMed ID: 20161793
PubMed ID: 20018651
Title: Beta-arrestin- but not G protein-mediated signaling by the 'decoy' receptor CXCR7.
PubMed ID: 20018651
PubMed ID: 21655198
Title: CXCR7 protein expression in human adult brain and differentiated neurons.
PubMed ID: 21655198
PubMed ID: 22698181
Title: The biochemistry and biology of the atypical chemokine receptors.
PubMed ID: 22698181
PubMed ID: 22300987
Title: Carboxy-terminus of CXCR7 regulates receptor localization and function.
PubMed ID: 22300987
PubMed ID: 22457824
Title: Ubiquitination of CXCR7 controls receptor trafficking.
PubMed ID: 22457824
PubMed ID: 23356288
Title: Atypical chemokine receptors: from silence to sound.
PubMed ID: 23356288
DOI: 10.1042/bst20120246
PubMed ID: 23153575
Title: CXCR7 impact on CXCL12 biology and disease.
PubMed ID: 23153575
PubMed ID: 31211835
Title: Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans.
PubMed ID: 31211835
DOI: 10.1093/hmg/ddz137
Sequence Information:
- Length: 362
- Mass: 41493
- Checksum: A863EC1AFB5B158B
- Sequence:
MDLHLFDYSE PGNFSDISWP CNSSDCIVVD TVMCPNMPNK SVLLYTLSFI YIFIFVIGMI ANSVVVWVNI QAKTTGYDTH CYILNLAIAD LWVVLTIPVW VVSLVQHNQW PMGELTCKVT HLIFSINLFG SIFFLTCMSV DRYLSITYFT NTPSSRKKMV RRVVCILVWL LAFCVSLPDT YYLKTVTSAS NNETYCRSFY PEHSIKEWLI GMELVSVVLG FAVPFSIIAV FYFLLARAIS ASSDQEKHSS RKIIFSYVVV FLVCWLPYHV AVLLDIFSIL HYIPFTCRLE HALFTALHVT QCLSLVHCCV NPVLYSFINR NYRYELMKAF IFKYSAKTGL TKLIDASRVS ETEYSALEQS TK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.