TBX20 | ENSG00000164532 | NCBI 57057

Details for: TBX20

Gene ID: 57057

Symbol: TBX20

Ensembl ID: ENSG00000164532

Description: T-box transcription factor 20

Associated with

Cardiogenesis
(R-HSA-9733709)
Developmental biology
(R-HSA-1266738)
Aortic valve morphogenesis
(GO:0003180)
Atrial septum morphogenesis
(GO:0060413)
Atrioventricular canal development
(GO:0036302)
Atrioventricular valve development
(GO:0003171)
Blood circulation
(GO:0008015)
Branching involved in blood vessel morphogenesis
(GO:0001569)
Cardiac chamber formation
(GO:0003207)
Cardiac muscle tissue morphogenesis
(GO:0055008)
Cardiac right ventricle morphogenesis
(GO:0003215)
Cardiac septum development
(GO:0003279)
Cell fate specification
(GO:0001708)
Cell population proliferation
(GO:0008283)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dorsal/ventral pattern formation
(GO:0009953)
Embryonic heart tube elongation
(GO:0036306)
Embryonic heart tube morphogenesis
(GO:0003143)
Endocardial cushion formation
(GO:0003272)
Endocardial cushion morphogenesis
(GO:0003203)
Endoderm formation
(GO:0001706)
Foramen ovale closure
(GO:0035922)
Heart looping
(GO:0001947)
Lateral mesoderm formation
(GO:0048370)
Mesenchymal cell development
(GO:0014031)
Motor neuron migration
(GO:0097475)
Muscle contraction
(GO:0006936)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of smad protein signal transduction
(GO:0060392)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Outflow tract septum morphogenesis
(GO:0003148)
Pericardium morphogenesis
(GO:0003344)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of bmp signaling pathway
(GO:0030513)
Positive regulation of cardiac muscle cell proliferation
(GO:0060045)
Positive regulation of cell cycle process
(GO:0090068)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Pulmonary valve formation
(GO:0003193)
Pulmonary vein morphogenesis
(GO:0060577)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sequence-specific double-stranded dna binding
(GO:1990837)
Tricuspid valve development
(GO:0003175)
Vasculogenesis
(GO:0001570)
Visceral motor neuron differentiation
(GO:0021524)

Other Information

Proteins

T-box transcription factor TBX20

Genular Protein ID: 3399622976

Symbol: TBX20_HUMAN

Name: T-box transcription factor TBX20

UniProtKB Accession Codes:

Q9UMR3 A4D1Y6 Q000T4 Q0IJ70 Q0VAS1 Q9Y2N5

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10936053

Title: Characterization of the human TBX20 gene, a new member of the T-box gene family closely related to the Drosophila H15 gene.

PubMed ID: 10936053

DOI: 10.1006/geno.2000.6249

PubMed ID: 17668378

Title: Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.

PubMed ID: 17668378

DOI: 10.1086/519530

PubMed ID: 19762328

Title: A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects.

PubMed ID: 19762328

DOI: 10.1136/jmg.2009.069997

Sequence Information:

Length: 447
Mass: 49232
Checksum: A6B43488373D81D1
Sequence:

MEFTASPKPQ LSSRANAFSI AALMSSGGSK EKEATENTIK PLEQFVEKSS CAQPLGELTS 
LDAHGEFGGG SGSSPSSSSL CTEPLIPTTP IIPSEEMAKI ACSLETKELW DKFHELGTEM 
IITKSGRRMF PTIRVSFSGV DPEAKYIVLM DIVPVDNKRY RYAYHRSSWL VAGKADPPLP 
ARLYVHPDSP FTGEQLLKQM VSFEKVKLTN NELDQHGHII LNSMHKYQPR VHIIKKKDHT 
ASLLNLKSEE FRTFIFPETV FTAVTAYQNQ LITKLKIDSN PFAKGFRDSS RLTDIERESV 
ESLIQKHSYA RSPIRTYGGE EDVLGDESQT TPNRGSAFTT SDNLSLSSWV SSSSSFPGFQ 
HPQSLTALGT STASIATPIP HPIQGSLPPY SRLGMPLTPS AIASSMQGSG PTFPSFHMPR 
YHHYFQQGPY AAIQGLRHSS AVMTPFV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TBX20

Associated with

Other Information

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the human TBX20 gene, a new member of the T-box gene family closely related to the Drosophila H15 gene. PubMed ID: 10936053

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. PubMed ID: 17668378