Details for: PNPLA2
Associated with
Other Information
Genular Protein ID: 1622245871
Symbol: PLPL2_HUMAN
Name: Desnutrin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15550674
Title: Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
PubMed ID: 15550674
PubMed ID: 15498874
Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.
PubMed ID: 15498874
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15364929
Title: Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.
PubMed ID: 15364929
PubMed ID: 16249444
Title: Adipocyte lipases and defect of lipolysis in human obesity.
PubMed ID: 16249444
PubMed ID: 16150821
Title: Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.
PubMed ID: 16150821
PubMed ID: 16705060
Title: The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma.
PubMed ID: 16705060
PubMed ID: 16239926
Title: ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells.
PubMed ID: 16239926
PubMed ID: 17032652
Title: Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor.
PubMed ID: 17032652
PubMed ID: 17603008
Title: A comparative study of human GS2, its paralogues, and its rat orthologue.
PubMed ID: 17603008
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22733971
Title: Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase.
PubMed ID: 22733971
DOI: 10.1210/en.2012-1127
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23297223
Title: Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
PubMed ID: 23297223
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 34903883
Title: Peroxisomal beta-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis.
PubMed ID: 34903883
PubMed ID: 35676490
Title: ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.
PubMed ID: 35676490
PubMed ID: 16644682
Title: The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes.
PubMed ID: 16644682
DOI: 10.2337/db05-1498
PubMed ID: 17187067
Title: The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy.
PubMed ID: 17187067
DOI: 10.1038/ng1951
Sequence Information:
- Length: 504
- Mass: 55316
- Checksum: D9C16F942AB0B3C7
- Sequence:
MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTR VSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQ GYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVP EDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQ LAGPAPLLST PAPEARPVIG ALGL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.