Details for: CD177

Gene ID: 57126

Symbol: CD177

Ensembl ID: ENSG00000204936

Description: CD177 molecule

Associated with

Other Information

Genular Protein ID: 2893143379

Symbol: CD177_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10753836

Title: Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera.

PubMed ID: 10753836

PubMed ID: 11465086

Title: Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immunenneutropenia and transfusion reactions.

PubMed ID: 11465086

DOI: 10.1002/1521-4141(200105)31:5<1301::aid-immu1301>3.0.co;2-j

PubMed ID: 12010833

Title: Molecular basis of NB1 (HNA-2a, CD177) deficiency.

PubMed ID: 12010833

DOI: 10.1182/blood.v99.11.4231

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 12239154

Title: Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera.

PubMed ID: 12239154

DOI: 10.1182/blood-2002-03-0949

PubMed ID: 12377969

Title: Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia.

PubMed ID: 12377969

DOI: 10.1200/jco.2002.11.507

PubMed ID: 12675722

Title: Expression of human neutrophil antigen-2a (NB1) is increased in pregnancy.

PubMed ID: 12675722

DOI: 10.1046/j.1537-2995.2003.00320.x

PubMed ID: 17244676

Title: NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.

PubMed ID: 17244676

DOI: 10.1182/blood-2006-10-055327

PubMed ID: 17580308

Title: The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).

PubMed ID: 17580308

DOI: 10.1074/jbc.m701120200

PubMed ID: 18462208

Title: Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing.

PubMed ID: 18462208

DOI: 10.1111/j.1365-2249.2008.03663.x

PubMed ID: 21193407

Title: Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.

PubMed ID: 21193407

DOI: 10.1074/jbc.m110.171256

PubMed ID: 23202369

Title: Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function.

PubMed ID: 23202369

DOI: 10.1161/atvbaha.112.300474

PubMed ID: 23461681

Title: Surface receptor CD177/NB1 does not confer a recruitment advantage to neutrophilic granulocytes during human peritonitis.

PubMed ID: 23461681

DOI: 10.1111/ejh.12095

PubMed ID: 24926686

Title: Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177.

PubMed ID: 24926686

DOI: 10.1371/journal.pone.0099671

PubMed ID: 28807980

Title: CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation.

PubMed ID: 28807980

DOI: 10.1182/blood-2017-03-768507

PubMed ID: 28240246

Title: Characterization of the CD177 interaction with the ANCA antigen proteinase 3.

PubMed ID: 28240246

DOI: 10.1038/srep43328

PubMed ID: 12623849

Title: Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP-neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms.

PubMed ID: 12623849

DOI: 10.1182/blood-2002-09-2831

PubMed ID: 14692971

Title: CD177 polymorphisms: correlation between high-frequency single nucleotide polymorphisms and neutrophil surface protein expression.

PubMed ID: 14692971

DOI: 10.1046/j.0041-1132.2004.00606.x

PubMed ID: 27227454

Title: Heterogeneity of human neutrophil CD177 expression results from CD177P1 pseudogene conversion.

PubMed ID: 27227454

DOI: 10.1371/journal.pgen.1006067

Sequence Information:

  • Length: 437
  • Mass: 46363
  • Checksum: 3D4716F221934910
  • Sequence:
  • MSAVLLLALL GFILPLPGVQ ALLCQFGTVQ HVWKVSDLPR QWTPKNTSCD SGLGCQDTLM 
    LIESGPQVSL VLSKGCTEAK DQEPRVTEHR MGPGLSLISY TFVCRQEDFC NNLVNSLPLW 
    APQPPADPGS LRCPVCLSME GCLEGTTEEI CPKGTTHCYD GLLRLRGGGI FSNLRVQGCM 
    PQPGCNLLNG TQEIGPVGMT ENCNRKDFLT CHRGTTIMTH GNLAQEPTDW TTSNTEMCEV 
    GQVCQETLLL LDVGLTSTLV GTKGCSTVGA QNSQKTTIHS APPGVLVASY THFCSSDLCN 
    SASSSSVLLN SLPPQAAPVP GDRQCPTCVQ PLGTCSSGSP RMTCPRGATH CYDGYIHLSG 
    GGLSTKMSIQ GCVAQPSSFL LNHTRQIGIF SAREKRDVQP PASQHEGGGA EGLESLTWGV 
    GLALAPALWW GVVCPSC

Genular Protein ID: 425400624

Symbol: A0A087WVM2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 437
  • Mass: 46381
  • Checksum: FDA06DDFCD610575
  • Sequence:
  • MSAVLLLALL GFILPLPGVQ ALLCQFGTVQ HVWKVSDLPR QWTPKNTSCD SGLGCQDTLM 
    LIESGPQVSL VLSKGCTEAK DQEPRVTEHR MGPGLSLISY TFVCRQEDFC NNLVNSLPLW 
    APQPPADPGS LRCPVCLSME GCLEGTTEEI CPKGTTHCYD GLLRLRGGGI FSNLRVQGCM 
    PQPVCNLLNG TQEIGPVGMT ENCDMKDFLT CHRGTTIMTH GNLAQEPTDW TTSNTEMCEV 
    GQVCQETLLL LDVGLTSTLV GTKGCSTVGA QNSQKTTIHS APPGVLVASY THFCSSDLCN 
    SASSSSVLLN SLPPQAAPVP GDRQCPTCVQ PLGTCSSGSP RMTCPRGATH CYDGYIHLSG 
    GGLSTKMSIQ GCVAQPSSFL LNHTRQIGIF SAREKRDVQP PASQHEGGGA EGLESLTWGV 
    GLALAPALWW GVVCPSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.