Associated with
Other Information
Genular Protein ID: 2759101381
Symbol: RTN4_HUMAN
Name: Foocen
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10773680
Title: Assignment of the human reticulon 4 gene (RTN4) to chromosome 2p14-->2p13 by radiation hybrid mapping.
PubMed ID: 10773680
DOI: 10.1159/000015499
PubMed ID: 10667780
PubMed ID: 11126360
Title: A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity.
PubMed ID: 11126360
PubMed ID: 11866689
Title: Expression of a novel reticulon-like gene in human testis.
PubMed ID: 11866689
PubMed ID: 12488097
Title: Genomic structure and functional characterisation of the promoters of human and mouse nogo/rtn4.
PubMed ID: 12488097
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 15498874
Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.
PubMed ID: 15498874
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10667797
Title: Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein.
PubMed ID: 10667797
DOI: 10.1038/35000226
PubMed ID: 11201742
Title: Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration.
PubMed ID: 11201742
DOI: 10.1038/35053072
PubMed ID: 11891768
Title: Nogos and the Nogo-66 receptor: factors inhibiting CNS neuron regeneration.
PubMed ID: 11891768
DOI: 10.1002/jnr.10134
PubMed ID: 12811824
Title: Pro-apoptotic ASY/Nogo-B protein associates with ASYIP.
PubMed ID: 12811824
DOI: 10.1002/jcp.10297
PubMed ID: 15034570
Title: A new role for Nogo as a regulator of vascular remodeling.
PubMed ID: 15034570
DOI: 10.1038/nm1020
PubMed ID: 15286784
Title: Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.
PubMed ID: 15286784
DOI: 10.1038/nm1088
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16965550
Title: Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein.
PubMed ID: 16965550
PubMed ID: 16979658
Title: Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins.
PubMed ID: 16979658
PubMed ID: 16835300
Title: Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells.
PubMed ID: 16835300
PubMed ID: 19052207
Title: Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.
PubMed ID: 19052207
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19665976
Title: A class of dynamin-like GTPases involved in the generation of the tubular ER network.
PubMed ID: 19665976
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 19699797
Title: GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth.
PubMed ID: 19699797
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21183689
Title: Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation.
PubMed ID: 21183689
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24262037
Title: Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.
PubMed ID: 24262037
DOI: 10.1042/bj20131186
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25612671
Title: Identification and characterization of TMEM33 as a reticulon-binding protein.
PubMed ID: 25612671
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27619977
Title: Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.
PubMed ID: 27619977
DOI: 10.7554/elife.18605
PubMed ID: 26906412
Title: Transmembrane protein TMEM170A is a novel regulator of ER and NE morphogenesis in human cells.
PubMed ID: 26906412
DOI: 10.1242/jcs.175273
PubMed ID: 27786289
Title: NOGO-A/RTN4A and NOGO-B/RTN4B are simultaneously expressed in epithelial, fibroblast and neuronal cells and maintain ER morphology.
PubMed ID: 27786289
DOI: 10.1038/srep35969
PubMed ID: 32075961
Title: REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
PubMed ID: 32075961
PubMed ID: 33826365
Title: RTN4B interacting protein FAM134C promotes ER membrane curvature and has a functional role in autophagy.
PubMed ID: 33826365
PubMed ID: 16877707
Title: Nogo goes in the pure water: solution structure of Nogo-60 and design of the structured and buffer-soluble Nogo-54 for enhancing CNS regeneration.
PubMed ID: 16877707
DOI: 10.1110/ps.062306906
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 1192
- Mass: 129931
- Checksum: CDE239BBF31589CA
- Sequence:
MEDLDQSPLV SSSDSPPRPQ PAFKYQFVRE PEDEEEEEEE EEEDEDEDLE ELEVLERKPA AGLSAAPVPT APAAGAPLMD FGNDFVPPAP RGPLPAAPPV APERQPSWDP SPVSSTVPAP SPLSAAAVSP SKLPEDDEPP ARPPPPPPAS VSPQAEPVWT PPAPAPAAPP STPAAPKRRG SSGSVDETLF ALPAASEPVI RSSAENMDLK EQPGNTISAG QEDFPSVLLE TAASLPSLSP LSAASFKEHE YLGNLSTVLP TEGTLQENVS EASKEVSEKA KTLLIDRDLT EFSELEYSEM GSSFSVSPKA ESAVIVANPR EEIIVKNKDE EEKLVSNNIL HNQQELPTAL TKLVKEDEVV SSEKAKDSFN EKRVAVEAPM REEYADFKPF ERVWEVKDSK EDSDMLAAGG KIESNLESKV DKKCFADSLE QTNHEKDSES SNDDTSFPST PEGIKDRSGA YITCAPFNPA ATESIATNIF PLLGDPTSEN KTDEKKIEEK KAQIVTEKNT STKTSNPFLV AAQDSETDYV TTDNLTKVTE EVVANMPEGL TPDLVQEACE SELNEVTGTK IAYETKMDLV QTSEVMQESL YPAAQLCPSF EESEATPSPV LPDIVMEAPL NSAVPSAGAS VIQPSSSPLE ASSVNYESIK HEPENPPPYE EAMSVSLKKV SGIKEEIKEP ENINAALQET EAPYISIACD LIKETKLSAE PAPDFSDYSE MAKVEQPVPD HSELVEDSSP DSEPVDLFSD DSIPDVPQKQ DETVMLVKES LTETSFESMI EYENKEKLSA LPPEGGKPYL ESFKLSLDNT KDTLLPDEVS TLSKKEKIPL QMEELSTAVY SNDDLFISKE AQIRETETFS DSSPIEIIDE FPTLISSKTD SFSKLAREYT DLEVSHKSEI ANAPDGAGSL PCTELPHDLS LKNIQPKVEE KISFSDDFSK NGSATSKVLL LPPDVSALAT QAEIESIVKP KVLVKEAEKK LPSDTEKEDR SPSAIFSAEL SKTSVVDLLY WRDIKKTGVV FGASLFLLLS LTVFSIVSVT AYIALALLSV TISFRIYKGV IQAIQKSDEG HPFRAYLESE VAISEELVQK YSNSALGHVN CTIKELRRLF LVDDLVDSLK FAVLMWVFTY VGALFNGLTL LILALISLFS VPVIYERHQA QIDHYLGLAN KNVKDAMAKI QAKIPGLKRK AE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.