Details for: SLURP1

Gene ID: 57152

Symbol: SLURP1

Ensembl ID: ENSG00000126233

Description: secreted LY6/PLAUR domain containing 1

Associated with

Other Information

Genular Protein ID: 684503806

Symbol: SLUR1_HUMAN

Name: Secreted Ly-6/uPAR-related protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16354194

Title: Biological effects of SLURP-1 on human keratinocytes.

PubMed ID: 16354194

DOI: 10.1111/j.0022-202x.2005.23973.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8742060

Title: Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes.

PubMed ID: 8742060

DOI: 10.1006/cyto.1996.0001

PubMed ID: 10211827

Title: Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily.

PubMed ID: 10211827

DOI: 10.1110/ps.8.4.810

PubMed ID: 14721776

Title: ARS component B: structural characterization, tissue expression and regulation of the gene and protein (SLURP-1) associated with Mal de Meleda.

PubMed ID: 14721776

PubMed ID: 14506129

Title: Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda.

PubMed ID: 14506129

DOI: 10.1093/hmg/ddg320

PubMed ID: 17008884

Title: SLURP1 is a late marker of epidermal differentiation and is absent in Mal de Meleda.

PubMed ID: 17008884

DOI: 10.1038/sj.jid.5700551

PubMed ID: 17286989

Title: Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands.

PubMed ID: 17286989

DOI: 10.1016/j.lfs.2006.12.028

PubMed ID: 11285253

Title: Mutations in the gene encoding SLURP-1 in Mal de Meleda.

PubMed ID: 11285253

DOI: 10.1093/hmg/10.8.875

PubMed ID: 20621062

Title: Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions.

PubMed ID: 20621062

DOI: 10.1016/j.bbrc.2010.07.006

PubMed ID: 25168896

Title: SLURP-1 modulates corneal homeostasis by serving as a soluble scavenger of urokinase-type plasminogen activator.

PubMed ID: 25168896

DOI: 10.1167/iovs.14-15107

PubMed ID: 25919322

Title: Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda.

PubMed ID: 25919322

DOI: 10.1111/bjd.13868

PubMed ID: 26905431

Title: Human secreted Ly-6/uPAR related protein-1 (SLURP-1) is a selective allosteric antagonist of alpha7 nicotinic acetylcholine receptor.

PubMed ID: 26905431

DOI: 10.1371/journal.pone.0149733

PubMed ID: 23581991

Title: Human neuromodulator SLURP-1: bacterial expression, binding to muscle-type nicotinic acetylcholine receptor, secondary structure, and conformational heterogeneity in solution.

PubMed ID: 23581991

DOI: 10.1134/s0006297913020090

PubMed ID: 33019770

Title: Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.

PubMed ID: 33019770

DOI: 10.3390/ijms21197280

PubMed ID: 12950349

Title: A novel mutation in the ARS (component B) gene encoding SLURP-1 in a family with Mal de Meleda.

PubMed ID: 12950349

DOI: 10.1046/j.1365-2230.2003.01342.x

PubMed ID: 12483299

Title: Mal de Meleda (MDM) caused by mutations in the gene for SLURP-1 in patients from Germany, Turkey, Palestine, and the United Arab Emirates.

PubMed ID: 12483299

DOI: 10.1007/s00439-002-0838-8

PubMed ID: 14756676

Title: Heterozygous manifestations in female carriers of Mal de Meleda.

PubMed ID: 14756676

DOI: 10.1111/j.0009-9163.2004.00224.x

PubMed ID: 19120323

Title: Compound heterozygosity for ARS component B mutations in a Dutch patient with mal de Meleda.

PubMed ID: 19120323

DOI: 10.1111/j.1365-2133.2008.08980.x

PubMed ID: 21690549

Title: A novel homozygous missense mutation in SLURP1 causing Mal de Meleda with an atypical phenotype.

PubMed ID: 21690549

DOI: 10.1001/archdermatol.2011.138

PubMed ID: 24604124

Title: Palmoplantar keratoderma of the Gamborg-Nielsen type is caused by mutations in the SLURP1 gene and represents a variant of Mal de Meleda.

PubMed ID: 24604124

DOI: 10.2340/00015555-1840

Sequence Information:

  • Length: 103
  • Mass: 11186
  • Checksum: 07AAF6BCA8031282
  • Sequence:
  • MASRWAVQLL LVAAWSMGCG EALKCYTCKE PMTSASCRTI TRCKPEDTAC MTTLVTVEAE 
    YPFNQSPVVT RSCSSSCVAT DPDSIGAAHL IFCCFRDLCN SEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.