Details for: TTC7A

Gene ID: 57217

Symbol: TTC7A

Ensembl ID: ENSG00000068724

Description: tetratricopeptide repeat domain 7A

Associated with

Other Information

Genular Protein ID: 4027935379

Symbol: TTC7A_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10574461

Title: Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

PubMed ID: 10574461

DOI: 10.1093/dnares/6.5.329

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23229899

Title: PtdIns4P synthesis by PI4KIIIalpha at the plasma membrane and its impact on plasma membrane identity.

PubMed ID: 23229899

DOI: 10.1083/jcb.201206095

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25546680

Title: Multiple intestinal atresia with combined immune deficiency related to TTC7A defect is a multiorgan pathology: study of a French-Canadian-based cohort.

PubMed ID: 25546680

DOI: 10.1097/md.0000000000000327

PubMed ID: 34415310

Title: Biallelic PI4KA variants cause neurological, intestinal and immunological disease.

PubMed ID: 34415310

DOI: 10.1093/brain/awab313

PubMed ID: 23830146

Title: Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias.

PubMed ID: 23830146

DOI: 10.1016/j.jaci.2013.06.013

PubMed ID: 23423984

Title: Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia.

PubMed ID: 23423984

DOI: 10.1136/jmedgenet-2012-101483

PubMed ID: 24417819

Title: Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

PubMed ID: 24417819

DOI: 10.1053/j.gastro.2014.01.015

PubMed ID: 24931897

Title: Tetratricopeptide repeat domain 7A (TTC7A) mutation in a newborn with multiple intestinal atresia and combined immunodeficiency.

PubMed ID: 24931897

DOI: 10.1007/s10875-014-0067-7

PubMed ID: 24292712

Title: TTC7A mutations disrupt intestinal epithelial apicobasal polarity.

PubMed ID: 24292712

DOI: 10.1172/jci71471

PubMed ID: 25745186

Title: Hypomorphic mutation in TTC7A causes combined immunodeficiency with mild structural intestinal defects.

PubMed ID: 25745186

DOI: 10.1182/blood-2014-08-595397

PubMed ID: 25534311

Title: Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency.

PubMed ID: 25534311

DOI: 10.1111/cge.12553

Sequence Information:

  • Length: 858
  • Mass: 96185
  • Checksum: 9D10411B48478171
  • Sequence:
  • MAAKGAHGSY LKVESELERC RAEGHWDRMP ELVRQLQTLS MPGGGGNRRG SPSAAFTFPD 
    TDDFGKLLLA EALLEQCLKE NHAKIKDSMP LLEKNEPKMS EAKNYLSSIL NHGRLSPQYM 
    CEAMLILGKL HYVEGSYRDA ISMYARAGID DMSMENKPLY QMRLLSEAFV IKGLSLERLP 
    NSIASRFRLT EREEEVITCF ERASWIAQVF LQELEKTTNN STSRHLKGCH PLDYELTYFL 
    EAALQSAYVK NLKKGNIVKG MRELREVLRT VETKATQNFK VMAAKHLAGV LLHSLSEECY 
    WSPLSHPLPE FMGKEESSFA TQALRKPHLY EGDNLYCPKD NIEEALLLLL ISESMATRDV 
    VLSRVPEQEE DRTVSLQNAA AIYDLLSITL GRRGQYVMLS ECLERAMKFA FGEFHLWYQV 
    ALSMVACGKS AYAVSLLREC VKLRPSDPTV PLMAAKVCIG SLRWLEEAEH FAMMVISLGE 
    EAGEFLPKGY LALGLTYSLQ ATDATLKSKQ DELHRKALQT LERAQQLAPS DPQVILYVSL 
    QLALVRQISS AMEQLQEALK VRKDDAHALH LLALLFSAQK HHQHALDVVN MAITEHPENF 
    NLMFTKVKLE QVLKGPEEAL VTCRQVLRLW QTLYSFSQLG GLEKDGSFGE GLTMKKQSGM 
    HLTLPDAHDA DSGSRRASSI AASRLEEAMS ELTMPSSVLK QGPMQLWTTL EQIWLQAAEL 
    FMEQQHLKEA GFCIQEAAGL FPTSHSVLYM RGRLAEVKGN LEEAKQLYKE ALTVNPDGVR 
    IMHSLGLMLS RLGHKSLAQK VLRDAVERQS TCHEAWQGLG EVLQAQGQNE AAVDCFLTAL 
    ELEASSPVLP FSIIPREL

Genular Protein ID: 1763361524

Symbol: I6L9J2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 504
  • Mass: 55992
  • Checksum: 305C2BA5669DFBB2
  • Sequence:
  • MATRDVVLSR VPEQEEDRTV SLQNAAAIYD LLSITLGRRG QYVMLSECLE RAMKFAFGEF 
    HLWYQVALSM VACGKSAYAV SLLRECVKLR PSDPTVPLMA AKVCIGSLRW LEEAEHFAMM 
    VISLGEEAGE FLPKGYLALG LTYSLQATDA TLKSKQDELH RKALQTLERA QQLAPSDPQV 
    ILYVSLQLAL VRQISSAMEQ LQEALKVRKD DAHALHLLAL LFSAQKHHQH ALDVVNMAIT 
    EHPGNFNLMF TKVKLEQVLK GPEEALVTCR QVLRLWQTLY SFSQLGGLEK DGSFGEGLTM 
    KKQSGMHLTL PDAHDADSGS RRASSIAASR LEEAMSELTM PSSVLKQGPM QLWTTLEQIW 
    LQAAELFMEQ QHLKEAGFCI QEAAGLFPTS HSVLYMRGRL AEVKGNLEEA KQLYKEALTV 
    NPDGVRIMHS LGLMLSRLGH KSLAQKVLRD AVERQSTCHE AWQGLGEVLQ AQGQNEAAVD 
    CFLTALELEA SSPVLPFSII PREL

Genular Protein ID: 2902825244

Symbol: B3KPK7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 824
  • Mass: 92654
  • Checksum: 94DAC75126DACE02
  • Sequence:
  • MVPSSSRTPG FKQSSHHLRL PKCWDYRDDF GKLLLAEALL EQCLKENHAK INDSMPLLEK 
    NEPKMSEAKN YLSSILNHGR LSPQYMCEAM LILGKLHYVE GSYRDAISMY ARAGIDDMSM 
    ENKPLYQMRL LSEAFVIKGL SLERLPNSIA SRFRLTEREE EVITCFERAS WIAQVFLQEL 
    EKTTNNSTSR HLKGCHPLDY ELTYFLEAAL QSAYVKNLKK GNIVKGMREL REVLRTVETK 
    ATQNFKVMAA KHLAGVLLHS LSEECYWSPL SHPLPEFMGK EESSFATQAL RKPHLYEGDN 
    LYCPKDNIEE ALLLLLISES MATRDVVLSR VPEQEEDRTV SLQNAAAIYD LLSITLGRRG 
    QYVMLSECLE RAMKFAFGEF HLWYQVALSM VACGKSAYAV SLLRECVKLR PSDPTVPLMA 
    AKVCIGSLRW LEEAEHFAMM VISLGEEAGE FLPKGYLALG LTYSLQATDA TLKSKQDELH 
    RKALQTLERA QQLAPSDPQV ILYVSLQLAL VRQISSAMEQ LQEALKVRKD DAHALHLLAL 
    LFSAQKHHQH ALDVVNMAIT EHPENFNLMF TKVKLEQVLK GPEEALVTCR QVLRLWQTLY 
    SFSQLGGLEK DGSFGEGLTM KKQSGMHLTL PDAHDADSGS RRASSIAASR LEEAMSELTM 
    PSSVLKQGPM QLWTTLGQIW LQAAELFMEQ QHLKEAGFCI QEAAGLFPTS HSVLYMRGRL 
    AEVKGNLEEA KQLYKEALTV NPDGVRIMHS LGLMLSRLGH KSLAQKVLRD AVERQSTCHE 
    AWQGLGEVLQ AQGQNEAAVD CFLTALELEA SSPVLPFSII PREL

Genular Protein ID: 1628415614

Symbol: G5E9G4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 824
  • Mass: 92740
  • Checksum: 610374DF00425F0E
  • Sequence:
  • MVPSSSRTPG FKQSSHHLRL PKCWDYRDDF GKLLLAEALL EQCLKENHAK IKDSMPLLEK 
    NEPKMSEAKN YLSSILNHGR LSPQYMCEAM LILGKLHYVE GSYRDAISMY ARAGIDDMSM 
    ENKPLYQMRL LSEAFVIKGL SLERLPNSIA SRFRLTEREE EVITCFERAS WIAQVFLQEL 
    EKTTNNSTSR HLKGCHPLDY ELTYFLEAAL QSAYVKNLKK GNIVKGMREL REVLRTVETK 
    ATQNFKVMAA KHLAGVLLHS LSEECYWSPL SHPLPEFMGK EESSFATQAL RKPHLYEGDN 
    LYCPKDNIEE ALLLLLISES MATRDVVLSR VPEQEEDRTV SLQNAAAIYD LLSITLGRRG 
    QYVMLSECLE RAMKFAFGEF HLWYQVALSM VACGKSAYAV SLLRECVKLR PSDPTVPLMA 
    AKVCIGSLRW LEEAEHFAMM VISLGEEAGE FLPKGYLALG LTYSLQATDA TLKSKQDELH 
    RKALQTLERA QQLAPSDPQV ILYVSLQLAL VRQISSAMEQ LQEALKVRKD DAHALHLLAL 
    LFSAQKHHQH ALDVVNMAIT EHPENFNLMF TKVKLEQVLK GPEEALVTCR QVLRLWQTLY 
    SFSQLGGLEK DGSFGEGLTM KKQSGMHLTL PDAHDADSGS RRASSIAASR LEEAMSELTM 
    PSSVLKQGPM QLWTTLEQIW LQAAELFMEQ QHLKEAGFCI QEAAGLFPTS HSVLYMRGRL 
    AEVKGNLEEA KQLYKEALTV NPDGVRIMHS LGLMLSRLGH KSLAQKVLRD AVERQSTCHE 
    AWQGLGEVLQ AQGQNEAAVD CFLTALELEA SSPVLPFSII PREL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.