Vav3 | ENSMUSG00000033721 | NCBI 57257

Details for: Vav3

Gene ID: 57257

Symbol: Vav3

Ensembl ID: ENSMUSG00000033721

Description: vav 3 oncogene

Associated with

Axon guidance
(R-MMU-422475)
Azathioprine adme
(R-MMU-9748787)
Cdc42 gtpase cycle
(R-MMU-9013148)
Cell death signalling via nrage, nrif and nade
(R-MMU-204998)
Dap12 interactions
(R-MMU-2172127)
Dap12 signaling
(R-MMU-2424491)
Death receptor signaling
(R-MMU-73887)
Developmental biology
(R-MMU-1266738)
Drug adme
(R-MMU-9748784)
Eph-ephrin mediated repulsion of cells
(R-MMU-3928665)
Eph-ephrin signaling
(R-MMU-2682334)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated ca+2 mobilization
(R-MMU-2871809)
Fceri mediated mapk activation
(R-MMU-2871796)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-MMU-2029480)
G alpha (12/13) signalling events
(R-MMU-416482)
Gpcr downstream signalling
(R-MMU-388396)
Gpvi-mediated activation cascade
(R-MMU-114604)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Nervous system development
(R-MMU-9675108)
Nrage signals death through jnk
(R-MMU-193648)
P75 ntr receptor-mediated signalling
(R-MMU-193704)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Regulation of actin dynamics for phagocytic cup formation
(R-MMU-2029482)
Rhoa gtpase cycle
(R-MMU-8980692)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by gpcr
(R-MMU-372790)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by vegf
(R-MMU-194138)
Signal transduction
(R-MMU-162582)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated vascular permeability
(R-MMU-5218920)
Angiogenesis
(GO:0001525)
B cell receptor signaling pathway
(GO:0050853)
Cell migration
(GO:0016477)
Cell projection assembly
(GO:0030031)
Cytoplasm
(GO:0005737)
Dna damage response
(GO:0006974)
Epidermal growth factor receptor binding
(GO:0005154)
Guanyl-nucleotide exchange factor activity
(GO:0005085)
Immunological synapse
(GO:0001772)
Integrin-mediated signaling pathway
(GO:0007229)
Intracellular signal transduction
(GO:0035556)
Lamellipodium assembly
(GO:0030032)
Metal ion binding
(GO:0046872)
Neutrophil chemotaxis
(GO:0030593)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Protein binding
(GO:0005515)
Regulation of gtpase activity
(GO:0043087)
Response to xenobiotic stimulus
(GO:0009410)
Small gtpase-mediated signal transduction
(GO:0007264)
Vesicle fusion
(GO:0006906)

Other Information

Proteins

Guanine nucleotide exchange factor VAV3

Genular Protein ID: 3489680484

Symbol: VAV3_MOUSE

Name: Guanine nucleotide exchange factor VAV3

UniProtKB Accession Codes:

Q9R0C8 A2CFD7 Q7TS85 Q8BRV2 Q8CCF5 Q8R076 Q9JLS6

Database IDs:

Citations:

PubMed ID: 10713454

Title: Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors.

PubMed ID: 10713454

DOI: 10.1016/s0378-1119(00)00026-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15711558

Title: Vav3 regulates osteoclast function and bone mass.

PubMed ID: 15711558

DOI: 10.1038/nm1194

PubMed ID: 16782872

Title: Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

PubMed ID: 16782872

DOI: 10.1128/mcb.02215-05

PubMed ID: 19147786

Title: Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.

PubMed ID: 19147786

DOI: 10.1182/blood-2008-07-166702

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 847
Mass: 97968
Checksum: 727C9BF50DF8CF19
Sequence:

MEPWKQCAQW LIHSKVLPPN HRVTWDSAQV FDLAQTLRDG VLLCQLLNNL RPHSINLKEI 
NLRPQMSQFL CLKNIRTFLA ACCDTFGMRK SELFEAFDLF DVRDFGKVIE TLSRLSRTPI 
ALATGIRPFP TEESINDEDI YKGLPDLIDE TRVEDEEDLY DCVYGEDEGG EVYEDLMKAE 
EAQQPKSQEN DIRSCCLAEI RQTEEKYTET LESIEKYFMA PLKRFLTAAE FDSVFINIPD 
LVKVHRSLMQ EIHDSIVNKD DQNLYQVFIN YKERLVIYGQ YCSGVESAIS NLDYISKTKE 
DVKLKLEECS KRANNGKFTL RDLLVVPMQR VLKYHLLLQE LVKHTHDPME KANLKLALDA 
MKDLAQYVNE VKRDNETLRE IKQFQLSIEN LNQPVLLFGR PQGDGEIRIT TLDKHTKQER 
HIFLFDLAVI VCKRKGDNYE MKEIIDLQQY KIANNPTTDK ENKKWSYGFY LIHTQGQNGL 
EFYCKTKDLK KKWLEQFEMA LSNIRPDYAD SNFHDFKMHT FTRVTSCRVC QMLLRGTFYQ 
GYLCFKCGAK AHKECLGRVD NCGRVNSVEQ GPFKPPEKRT NGLRRASRQV DPGLPKMQVI 
RNYTGTPAPG LHEGPPLHIQ AGDTVELLRG DAHSVFWQGR NLASGEVGFF PSDAVKPSPC 
VPKPVDYSCQ PWYAGPMERL QAETELINRV NSTYLVRHRT KESGEYAISI KYNNEAKHIK 
ILTRDGFFHI AENRKFKSLM ELVEYYKHHS LKEGFRTLDT TLQFPYKEPE QPAGQRGNRT 
GNSLLSPKVL GIAIARYDFC ARDMRELSLL KGDMVKIYTK MSANGWWRGE VNGRVGWFPS 
TYVEEDE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vav3

Associated with

Other Information

Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors. PubMed ID: 10713454

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Vav3 regulates osteoclast function and bone mass. PubMed ID: 15711558

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. PubMed ID: 16782872

Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils. PubMed ID: 19147786

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079