Details for: Brd4
Associated with
Other Information
Genular Protein ID: 3036199418
Symbol: BRD4_MOUSE
Name: Bromodomain-containing protein 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10938129
Title: A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition.
PubMed ID: 10938129
PubMed ID: 11997514
Title: Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.
PubMed ID: 11997514
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 12840145
Title: The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.
PubMed ID: 12840145
PubMed ID: 16109376
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
PubMed ID: 16109376
PubMed ID: 17267518
Title: Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis.
PubMed ID: 17267518
PubMed ID: 21814200
Title: RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
PubMed ID: 21814200
DOI: 10.1038/nature10334
PubMed ID: 21964340
Title: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
PubMed ID: 21964340
DOI: 10.1038/nature10509
PubMed ID: 22567088
Title: Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress.
PubMed ID: 22567088
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
PubMed ID: 19828451
Title: Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution.
PubMed ID: 19828451
PubMed ID: 20715035
Title: Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains.
PubMed ID: 20715035
Sequence Information:
- Length: 1400
- Mass: 155895
- Checksum: 3D90F6D3254D5691
- Sequence:
MSTESGPGTR LRNLPVMGDG LETSQMSTTQ AQAQPQPANA ASTNPPPPET SNPNKPKRQT NQLQYLLRVV LKTLWKHQFA WPFQQPVDAV KLNLPDYYKI IKTPMDMGTI KKRLENNYYW NAQECIQDFN TMFTNCYIYN KPGDDIVLMA EALEKLFLQK INELPTEETE IMIVQAKGRG RGRKETGAAK PGVSTVPNTT QASTSPQTQT PQQNPPPPVQ ATTHPFPAVT PDLIAQPPVM TMVPPQPLQT PSPVPPQPPP PPAPVPQPVQ SHPPIIATTP QPVKTKKGVK RKADTTTPTT IDPIHEPPSL APEPKTAKLG PRRESSRPVK PPKKDVPDSQ QHPGPEKSSK ISEQLKCCSG ILKEMFAKKH AAYAWPFYKP VDVEALGLHD YCDIIKHPMD MSTIKSKLES REYRDAQEFG ADVRLMFSNC YKYNPPDHEV VAMARKLQDV FEMRFAKMPD EPEEPVVTVS SPAVPPPTKV VAPPSSSDSS SDSSSDSDSS TDDSEEERAQ RLAELQEQLK AVHEQLAALS QPQQNKPKKK EKDKKEKKKE KHKKKEEVEE NKKSKTKELP PKKTKKNNSS NSNVSKKEPV PTKTKPPPTY ESEEEDKCKP MSYEEKRQLS LDINKLPGEK LGRVVHIIQS REPSLKNSNP DEIEIDFETL KPSTLRELER YVTSCLRKKR KPQAEKVDVI AGSSKMKGFS SSESESTSES SSSDSEDSET EMAPKSKKKG HTGRDQKKHH HHHHPQMQPA PAPVPQQPPP PPQQPPPPPP PQQQQQQPPP PPPPPSMPQQ TAPAMKSSPP PFITAQVPVL EPQLPGSVFD PIGHFTQPIL HLPQPELPPH LPQPPEHSTP PHLNQHAVVS PPALHNALPQ QPSRPSNRAA ALPPKPTRPP AVSPALAQPP LLPQPPMAQP PQVLLEDEEP PAPPLTSMQM QLYLQQLQKV QPPTPLLPSV KVQSQPPPPL PPPPHPSVQQ QQLQPQPPPP PPPQPQPPPQ QQHQPPPRPV HLPSMPFSAH IQQPPPPPGQ QPTHPPPGQQ PPPPQPAKPQ QVIQHHPSPR HHKSDPYSAG HLREAPSPLM IHSPQMPQFQ SLTHQSPPQQ NVQPKKQVKG RAEPQPPGPV MGQGQGCPPA SPAAVPMLSQ ELRPPSVVQP QPLVVVKEEK IHSPIIRSEP FSTSLRPEPP KHPENIKAPV HLPQRPEMKP VDIGRPVIRP PEQSAPPPGA PDKDKQKQEP KTPVAPKKDL KIKNMGSWAS LVQKHPTTPS STAKSSSDSF EHFRRAAREK EEREKALKAQ AEHAEKEKER LRQERMRSRE DEDALEQARR AHEEARRRQE QQQQQQQQRQ EQQQQQQQAA AVAAASAPQA QSSQPQSMLD QQRELARKRE QERRRREAMA ATIDMNFQSD LLSIFEENLF
Genular Protein ID: 3738318519
Symbol: B2RSE4_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 723
- Mass: 80605
- Checksum: F1115540F58A56B8
- Sequence:
MSTESGPGTR LRNLPVMGDG LETSQMSTTQ AQAQPQPANA ASTNPPPPET SNPNKPKRQT NQLQYLLRVV LKTLWKHQFA WPFQQPVDAV KLNLPDYYKI IKTPMDMGTI KKRLENNYYW NAQECIQDFN TMFTNCYIYN KPGDDIVLMA EALEKLFLQK INELPTEETE IMIVQAKGRG RGRKETGAAK PGVSTVPNTT QASTSPQTQT PQQNPPPPVQ ATTHPFPAVT PDLIAQPPVM TMVPPQPLQT PSPVPPQPPP PPAPVPQPVQ SHPPIIATTP QPVKTKKGVK RKADTTTPTT IDPIHEPPSL APEPKTAKLG PRRESSRPVK PPKKDVPDSQ QHPGPEKSSK ISEQLKCCSG ILKEMFAKKH AAYAWPFYKP VDVEALGLHD YCDIIKHPMD MSTIKSKLES REYRDAQEFG ADVRLMFSNC YKYNPPDHEV VAMARKLQDV FEMRFAKMPD EPEEPVVTVS SPAVPPPTKV VAPPSSSDSS SDSSSDSDSS TDDSEEERAQ RLAELQEQLK AVHEQLAALS QPQQNKPKKK EKDKKEKKKE KHKKKEEVEE NKKSKTKELP PKKTKKNNSS NSNVSKKEPV PTKTKPPPTY ESEEEDKCKP MSYEEKRQLS LDINKLPGEK LGRVVHIIQS REPSLKNSNP DEIEIDFETL KPSTLRELER YVTSCLRKKR KPQAEKVDVI AGSSKMKGFS SSESESTSES SSSDSEDSET GPA
Genular Protein ID: 1008512879
Symbol: Q3UH70_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10349636
Title: High-efficiency full-length cDNA cloning.
PubMed ID: 10349636
PubMed ID: 11042159
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
PubMed ID: 11042159
DOI: 10.1101/gr.145100
PubMed ID: 11076861
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
PubMed ID: 11076861
DOI: 10.1101/gr.152600
PubMed ID: 11217851
Title: Functional annotation of a full-length mouse cDNA collection.
PubMed ID: 11217851
DOI: 10.1038/35055500
PubMed ID: 12466851
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
PubMed ID: 12466851
DOI: 10.1038/nature01266
PubMed ID: 16141073
Title: Antisense Transcription in the Mammalian Transcriptome.
PubMed ID: 16141073
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
Sequence Information:
- Length: 1401
- Mass: 156051
- Checksum: CCBD767AA9F3EBED
- Sequence:
MSTESGPGTR LRNLPVMGDG LETSQMSTTQ AQAQPQPANA ASTNPPPPET SNPNKPKRQT NQLQYLLRVV LKTLWKHQFA WPFQQPVDAV KLNLPDYYKI IKTPMDMGTI KKRLENNYYW NAQECIQDFN TMFTNCYIYN KPGDDIVLMA EALEKLFLQK INELPTEETE IMIVQAKGRG RGRKETGRAA KPGVSTVPNT TQASTSPQTQ TPQQNPPPPV QATTHPFPAV TPDLIAQPPV MTMVPPQPLQ TPSPVPPQPP PPPAPVPQPV QSHPPIIATT PQPVKTKKGV KRKADTTTPT TIDPIHEPPS LAPEPKTAKL GPRRESSRPV KPPKKDVPDS QQHPGPEKSS KISEQLKCCS GILKEMFAKK HAAYAWPFYK PVDVEALGLH DYCDIIKHPM DMSTIKSKLE SREYRDAQEF GADVRLMFSN CYKYNPPDHE VVAMARKLQD VFEMRFAKMP DEPEEPVVTV SSPAVPPPTK VVAPPSSSDS SSDSSSDSDS STDDSEEERA QRLAELQEQL KAVHEQLAAL SQPQQNKPKK KEKDKKEKKK EKHKKKEEVE ENKKSKTKEL PPKKTKKNNS SNSNVSKKEP VPTKTKPPPT YESEEEDKCK PMSYEEKRQL SLDINKLPGE KLGRVVHIIQ SREPSLKNSN PDEIEIDFET LKPSTLRELE RYVTSCLRKK RKPQAEKVDV IAGSSKMKGF SSSESESTSE SSSSDSEDSE TEMAPKSKKK GHTGRDQKKH HHHHHPQMQP APAPVPQQPP PPPQQPPPPP PPQQQQQQPP PPPPPPSMPQ QTAPAMKSSP PPFITAQVPV LEPQLPGSVF DPIGHFTQPI LHLPQPELPP HLPQPPEHST PPHLNQHAVV SPPALHNALP QQPSRPSNRA AALPPKPTRP PAVSPALAQP PLLPQPPMAQ PPQVLLEDEE PPAPPLTSMQ MQLYLQQLQK VQPPTPLLPS VKVQSQPPPP LPPPPHPSVQ QQQLQPQPPP PPPPQPQPPP QQQHQPPPRP VHLPSMPFSA HIQQPPPPPG QQPTHPPPGQ QPPPPQPAKP QQVIQHHPSP RHHKSDPYSA GHLREAPSPL MIHSPQMPQF QSLTHQSPPQ QNVQPKKQVK GRAEPQPPGP VMGQGQGCPP ASPAAVPMLS QELRPPSVVQ PQPLVVVKEE KIHSPIIRSE PFSTSLRPEP PKHPENIKAP VHLPQRPEMK PVDIGRPVIR PPEQSAPPPG APDKDKQKQE PKTPVAPKKD LKIKNMGSWA SLVQKHPTTP SSTAKSSSDS FEHFRRAARE KEEREKALKA QAEHAEKEKE RLRQERMRSR EDEDALEQAR RAHEEARRRQ EQQQQQQQQR QEQQQQQQQA AAVAAASAPQ AQSSQPQSML DQQRELARKR EQERRRREAM AATIDMNFQS DLLSIFEENL F
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.