ABHD6 | ENSG00000163686 | NCBI 57406

Details for: ABHD6

Gene ID: 57406

Symbol: ABHD6

Ensembl ID: ENSG00000163686

Description: abhydrolase domain containing 6, acylglycerol lipase

Associated with

Arachidonate production from dag
(R-HSA-426048)
Effects of pip2 hydrolysis
(R-HSA-114508)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Hemostasis
(R-HSA-109582)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Acylglycerol catabolic process
(GO:0046464)
Acylglycerol lipase activity
(GO:0047372)
Ampa glutamate receptor complex
(GO:0032281)
Arachidonic acid metabolic process
(GO:0019369)
Gaba-ergic synapse
(GO:0098982)
Glutamatergic synapse
(GO:0098978)
Late endosome membrane
(GO:0031902)
Long-term synaptic depression
(GO:0060292)
Lysobisphosphatidic acid metabolic process
(GO:2001311)
Lysosomal membrane
(GO:0005765)
Membrane
(GO:0016020)
Mitochondrial membrane
(GO:0031966)
Mitochondrion
(GO:0005739)
Monoacylglycerol catabolic process
(GO:0052651)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of cold-induced thermogenesis
(GO:0120163)
Phospholipase activity
(GO:0004620)
Phospholipid catabolic process
(GO:0009395)
Plasma membrane
(GO:0005886)
Positive regulation of lipid biosynthetic process
(GO:0046889)
Postsynaptic membrane
(GO:0045211)
Protein binding
(GO:0005515)
Regulation of endocannabinoid signaling pathway
(GO:2000124)
Regulation of retrograde trans-synaptic signaling by endocanabinoid
(GO:0099178)

Other Information

Proteins

ABHD6_HUMAN

Genular Protein ID: 1101626379

Symbol: ABHD6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9BV23 B2R7Y9 Q6ZMF7

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22969151

Title: Biochemical and pharmacological characterization of human alpha/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).

PubMed ID: 22969151

DOI: 10.1194/jlr.m030411

PubMed ID: 26491015

Title: alpha/beta hydrolase domain-containing 6 (ABHD6) degrades the late endosomal/lysosomal lipid bis(monoacylglycero)phosphate.

PubMed ID: 26491015

DOI: 10.1074/jbc.m115.669168

Sequence Information:

Length: 337
Mass: 38331
Checksum: D87CEE8316F94910
Sequence:

MDLDVVNMFV IAGGTLAIPI LAFVASFLLW PSALIRIYYW YWRRTLGMQV RYVHHEDYQF 
CYSFRGRPGH KPSILMLHGF SAHKDMWLSV VKFLPKNLHL VCVDMPGHEG TTRSSLDDLS 
IDGQVKRIHQ FVECLKLNKK PFHLVGTSMG GQVAGVYAAY YPSDVSSLCL VCPAGLQYST 
DNQFVQRLKE LQGSAAVEKI PLIPSTPEEM SEMLQLCSYV RFKVPQQILQ GLVDVRIPHN 
NFYRKLFLEI VSEKSRYSLH QNMDKIKVPT QIIWGKQDQV LDVSGADMLA KSIANCQVEL 
LENCGHSVVM ERPRKTAKLI IDFLASVHNT DNNKKLD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ABHD6

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334