Details for: PLEKHG5

Gene ID: 57449

Symbol: PLEKHG5

Ensembl ID: ENSG00000171680

Description: pleckstrin homology and RhoGEF domain containing G5

Associated with

Other Information

Genular Protein ID: 1030804860

Symbol: PKHG5_HUMAN

Name: Pleckstrin homology domain-containing family G member 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12761501

Title: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

PubMed ID: 12761501

DOI: 10.1038/sj.onc.1206406

PubMed ID: 11704860

Title: The gene for a new brain specific RhoA exchange factor maps to the highly unstable chromosomal region 1p36.2-1p36.3.

PubMed ID: 11704860

DOI: 10.1038/sj.onc.1204921

PubMed ID: 16467373

Title: A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype.

PubMed ID: 16467373

DOI: 10.1091/mbc.e06-01-0002

PubMed ID: 23777631

Title: PLEKHG5 deficiency leads to an intermediate form of autosomal-recessive Charcot-Marie-Tooth disease.

PubMed ID: 23777631

DOI: 10.1093/hmg/ddt274

PubMed ID: 28847484

Title: The Rho-specific guanine nucleotide exchange factor Plekhg5 modulates cell polarity, adhesion, migration, and podosome organization in macrophages and osteoclasts.

PubMed ID: 28847484

DOI: 10.1016/j.yexcr.2017.08.025

PubMed ID: 17564964

Title: The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset.

PubMed ID: 17564964

DOI: 10.1086/518900

PubMed ID: 23844677

Title: Mutations in the PLEKHG5 gene is relevant with autosomal recessive intermediate Charcot-Marie-Tooth disease.

PubMed ID: 23844677

DOI: 10.1186/1750-1172-8-104

Sequence Information:

  • Length: 1006
  • Mass: 111231
  • Checksum: 2260D175D3C27D76
  • Sequence:
  • MHYDGHVRFD LPPQGSVLAR NVSTRSCPPR TSPAVDLEEE EEESSVDGKG DRKSTGLKLS 
    KKKARRRHTD DPSKECFTLK FDLNVDIETE IVPAMKKKSL GEVLLPVFER KGIALGKVDI 
    YLDQSNTPLS LTFEAYRFGG HYLRVKAPAK PGDEGKVEQG MKDSKSLSLP ILRPAGTGPP 
    ALERVDAQSR RESLDILAPG RRRKNMSEFL GEASIPGQEP PTPSSCSLPS GSSGSTNTGD 
    SWKNRAASRF SGFFSSGPST SAFGREVDKM EQLEGKLHTY SLFGLPRLPR GLRFDHDSWE 
    EEYDEDEDED NACLRLEDSW RELIDGHEKL TRRQCHQQEA VWELLHTEAS YIRKLRVIIN 
    LFLCCLLNLQ ESGLLCEVEA ERLFSNIPEI AQLHRRLWAS VMAPVLEKAR RTRALLQPGD 
    FLKGFKMFGS LFKPYIRYCM EEEGCMEYMR GLLRDNDLFR AYITWAEKHP QCQRLKLSDM 
    LAKPHQRLTK YPLLLKSVLR KTEEPRAKEA VVAMIGSVER FIHHVNACMR QRQERQRLAA 
    VVSRIDAYEV VESSSDEVDK LLKEFLHLDL TAPIPGASPE ETRQLLLEGS LRMKEGKDSK 
    MDVYCFLFTD LLLVTKAVKK AERTRVIRPP LLVDKIVCRE LRDPGSFLLI YLNEFHSAVG 
    AYTFQASGQA LCRGWVDTIY NAQNQLQQLR AQEPPGSQQP LQSLEEEEDE QEEEEEEEEE 
    EEEGEDSGTS AASSPTIMRK SSGSPDSQHC ASDGSTETLA MVVVEPGDTL SSPEFDSGPF 
    SSQSDETSLS TTASSATPTS ELLPLGPVDG RSCSMDSAYG TLSPTSLQDF VAPGPMAELV 
    PRAPESPRVP SPPPSPRLRR RTPVQLLSCP PHLLKSKSEA SLLQLLAGAG THGTPSAPSR 
    SLSELCLAVP APGIRTQGSP QEAGPSWDCR GAPSPGSGPG LVGCLAGEPA GSHRKRCGDL 
    PSGASPRVQP EPPPGVSAQH RKLTLAQLYR IRTTLLLNST LTASEV

Genular Protein ID: 3145960689

Symbol: A0A804EMX3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 1075
  • Mass: 118479
  • Checksum: FEC80DA35C9023F7
  • Sequence:
  • MGTGPGVSGR LAASRPGPGL PLRDSEPSWA GGRARDGDSQ VCHHADCQQL HRRGPLNLCE 
    ACDSKFHSTM HYDGHVRFDL PPQGSVLARN VSTRSCPPRT SPAVDLEEEE EESSVDGKGD 
    RKSTGLKLSK KKARRRHTDD PSKECFTLKF DLNVDIETEI VPAMKKKSLG EVLLPVFERK 
    GIALGKVDIY LDQSNTPLSL TFEAYRFGGH YLRVKAPAKP GDEGKVEQGM KDSKSLSLPI 
    LRPAGTGPPA LERVDAQSRR ESLDILAPGR RRKNMSEFLG EASIPGQEPP TPSSCSLPSG 
    SSGSTNTGDS WKNRAASRFS GFFSSGPSTS AFGREVDKME QLEGKLHTYS LFGLPRLPRG 
    LRFDHDSWEE EYDEDEDEDN ACLRLEDSWR ELIDGHEKLT RRQCHQQEAV WELLHTEASY 
    IRKLRVIINL FLCCLLNLQE SGLLCEVEAE RLFSNIPEIA QLHRRLWASV MAPVLEKARR 
    TRALLQPGDF LKGFKMFGSL FKPYIRYCME EEGCMEYMRG LLRDNDLFRA YITWAEKHPQ 
    CQRLKLSDML AKPHQRLTKY PLLLKSVLRK TEEPRAKEAV VAMIGSVERF IHHVNACMRQ 
    RQERQRLAAV VSRIDAYEVV ESSSDEVDKL LKEFLHLDLT APIPGASPEE TRQLLLEGSL 
    RMKEGKDSKM DVYCFLFTDL LLVTKAVKKA ERTRVIRPPL LVDKIVCREL RDPGSFLLIY 
    LNEFHSAVGA YTFQASGQAL CRGWVDTIYN AQNQLQQLRA QEPPGSQQPL QSLEEEEDEQ 
    EEEEEEEEEE EEGEDSGTSA ASSPTIMRKS SGSPDSQHCA SDGSTETLAM VVVEPGDTLS 
    SPEFDSGPFS SQSDETSLST TASSATPTSE LLPLGPVDGR SCSMDSAYGT LSPTSLQDFV 
    APGPMAELVP RAPESPRVPS PPPSPRLRRR TPVQLLSCPP HLLKSKSEAS LLQLLAGAGT 
    HGTPSAPSRS LSELCLAVPA PGIRTQGSPQ EAGPSWDCRG APSPGSGPGL VGCLAGEPAG 
    SHRKRCGDLP SGASPRVQPE PPPGVSAQHR KLTLAQLYRI RTTLLLNSTL TASEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.