Details for: ADGRB1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.6904
Cell Significance Index: 103.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.5693
Cell Significance Index: 314.8000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.3702
Cell Significance Index: 39.1000 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.0682
Cell Significance Index: 14.2500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.9292
Cell Significance Index: 41.1000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.8131
Cell Significance Index: 30.7900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6157
Cell Significance Index: 425.8500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5595
Cell Significance Index: 200.6900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.4729
Cell Significance Index: 31.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.4026
Cell Significance Index: 12.9000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3181
Cell Significance Index: 60.5400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3133
Cell Significance Index: 31.0000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2854
Cell Significance Index: 257.7100 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.1956
Cell Significance Index: 1.5000 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.1064
Cell Significance Index: 1.3800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0779
Cell Significance Index: 12.6800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.0573
Cell Significance Index: 0.9900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0478
Cell Significance Index: 2.9400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0165
Cell Significance Index: 1.8000 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.0127
Cell Significance Index: 0.1400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0110
Cell Significance Index: 0.5000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0028
Cell Significance Index: 0.0400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0007
Cell Significance Index: 0.0200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0039
Cell Significance Index: -0.1100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0046
Cell Significance Index: -2.0400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0055
Cell Significance Index: -10.4100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0061
Cell Significance Index: -11.1900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0079
Cell Significance Index: -12.2100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0103
Cell Significance Index: -14.0100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0107
Cell Significance Index: -0.5400 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0115
Cell Significance Index: -0.5000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0120
Cell Significance Index: -0.4200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0167
Cell Significance Index: -12.2700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0173
Cell Significance Index: -12.7900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0183
Cell Significance Index: -13.8600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0190
Cell Significance Index: -12.0700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0204
Cell Significance Index: -0.4900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0218
Cell Significance Index: -12.3000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0243
Cell Significance Index: -13.2900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0282
Cell Significance Index: -12.7900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0349
Cell Significance Index: -0.7400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0368
Cell Significance Index: -10.5800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0377
Cell Significance Index: -1.5400 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0454
Cell Significance Index: -0.9800 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0494
Cell Significance Index: -0.4700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0496
Cell Significance Index: -0.9800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0530
Cell Significance Index: -9.5600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0604
Cell Significance Index: -1.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0620
Cell Significance Index: -12.3100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0656
Cell Significance Index: -11.2000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0703
Cell Significance Index: -14.8000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0752
Cell Significance Index: -2.4000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0762
Cell Significance Index: -11.0700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0859
Cell Significance Index: -11.7900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0872
Cell Significance Index: -6.0300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0896
Cell Significance Index: -11.4900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0909
Cell Significance Index: -11.1800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0947
Cell Significance Index: -12.2300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0955
Cell Significance Index: -11.1300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1063
Cell Significance Index: -12.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1065
Cell Significance Index: -5.5900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1167
Cell Significance Index: -3.8200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1203
Cell Significance Index: -14.1900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1241
Cell Significance Index: -3.1900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1252
Cell Significance Index: -12.7900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1297
Cell Significance Index: -13.5100 - Cell Name: neuron (CL0000540)
Fold Change: -0.1361
Cell Significance Index: -1.2900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1415
Cell Significance Index: -2.8400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1450
Cell Significance Index: -7.5300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1461
Cell Significance Index: -10.3300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1504
Cell Significance Index: -3.1200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1619
Cell Significance Index: -12.4300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1829
Cell Significance Index: -13.6300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1915
Cell Significance Index: -6.7100 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.1937
Cell Significance Index: -2.1100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2019
Cell Significance Index: -11.3300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2032
Cell Significance Index: -4.2400 - Cell Name: neural cell (CL0002319)
Fold Change: -0.2109
Cell Significance Index: -2.4600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.2142
Cell Significance Index: -4.6400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2173
Cell Significance Index: -10.1300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2203
Cell Significance Index: -14.2100 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2209
Cell Significance Index: -5.5100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2289
Cell Significance Index: -13.7400 - Cell Name: mature astrocyte (CL0002627)
Fold Change: -0.2347
Cell Significance Index: -2.6100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2521
Cell Significance Index: -11.8500 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.2700
Cell Significance Index: -3.0900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2750
Cell Significance Index: -9.5600 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.2900
Cell Significance Index: -3.5200 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.2969
Cell Significance Index: -3.5500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.3160
Cell Significance Index: -6.2200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3195
Cell Significance Index: -8.4000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3217
Cell Significance Index: -4.0600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.3249
Cell Significance Index: -4.0300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.3322
Cell Significance Index: -7.0800 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.3386
Cell Significance Index: -2.8000 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: -0.3573
Cell Significance Index: -3.2300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.3600
Cell Significance Index: -4.0900 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.3614
Cell Significance Index: -4.5600 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.3762
Cell Significance Index: -2.9000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3879
Cell Significance Index: -14.2400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3183555813
Symbol: AGRB1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9393972
Title: A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis.
PubMed ID: 9393972
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 9647739
Title: Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.
PubMed ID: 9647739
PubMed ID: 9790924
Title: Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1.
PubMed ID: 9790924
PubMed ID: 10343108
Title: Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1.
PubMed ID: 10343108
DOI: 10.1159/000015219
PubMed ID: 10748157
Title: Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.
PubMed ID: 10748157
PubMed ID: 11875720
Title: Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis.
PubMed ID: 11875720
PubMed ID: 12074842
Title: Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells.
PubMed ID: 12074842
PubMed ID: 12507886
Title: Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression.
PubMed ID: 12507886
PubMed ID: 15782143
Title: Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor.
PubMed ID: 15782143
PubMed ID: 19176395
Title: Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.
PubMed ID: 19176395
PubMed ID: 22333914
Title: A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
PubMed ID: 22333914
PubMed ID: 22330140
Title: A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1.
PubMed ID: 22330140
DOI: 10.1038/onc.2012.1
PubMed ID: 23782696
Title: Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.
PubMed ID: 23782696
PubMed ID: 23595754
Title: The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.
PubMed ID: 23595754
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24509909
Title: Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells.
PubMed ID: 24509909
DOI: 10.1096/fj.13-243238
PubMed ID: 26710850
Title: Stalk-dependent and stalk-independent signaling by the adhesion G protein-coupled receptors GPR56 (ADGRG1) and BAI1 (ADGRB1).
PubMed ID: 26710850
PubMed ID: 26838550
Title: The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.
PubMed ID: 26838550
Sequence Information:
- Length: 1584
- Mass: 173501
- Checksum: A604E634DDD741F7
- Sequence:
MRGQAAAPGP VWILAPLLLL LLLLGRRARA AAGADAGPGP EPCATLVQGK FFGYFSAAAV FPANASRCSW TLRNPDPRRY TLYMKVAKAP VPCSGPGRVR TYQFDSFLES TRTYLGVESF DEVLRLCDPS APLAFLQASK QFLQMRRQQP PQHDGLRPRA GPPGPTDDFS VEYLVVGNRN PSRAACQMLC RWLDACLAGS RSSHPCGIMQ TPCACLGGEA GGPAAGPLAP RGDVCLRDAV AGGPENCLTS LTQDRGGHGA TGGWKLWSLW GECTRDCGGG LQTRTRTCLP APGVEGGGCE GVLEEGRQCN REACGPAGRT SSRSQSLRST DARRREELGD ELQQFGFPAP QTGDPAAEEW SPWSVCSSTC GEGWQTRTRF CVSSSYSTQC SGPLREQRLC NNSAVCPVHG AWDEWSPWSL CSSTCGRGFR DRTRTCRPPQ FGGNPCEGPE KQTKFCNIAL CPGRAVDGNW NEWSSWSACS ASCSQGRQQR TRECNGPSYG GAECQGHWVE TRDCFLQQCP VDGKWQAWAS WGSCSVTCGA GSQRRERVCS GPFFGGAACQ GPQDEYRQCG TQRCPEPHEI CDEDNFGAVI WKETPAGEVA AVRCPRNATG LILRRCELDE EGIAYWEPPT YIRCVSIDYR NIQMMTREHL AKAQRGLPGE GVSEVIQTLV EISQDGTSYS GDLLSTIDVL RNMTEIFRRA YYSPTPGDVQ NFVQILSNLL AEENRDKWEE AQLAGPNAKE LFRLVEDFVD VIGFRMKDLR DAYQVTDNLV LSIHKLPASG ATDISFPMKG WRATGDWAKV PEDRVTVSKS VFSTGLTEAD EASVFVVGTV LYRNLGSFLA LQRNTTVLNS KVISVTVKPP PRSLRTPLEI EFAHMYNGTT NQTCILWDET DVPSSSAPPQ LGPWSWRGCR TVPLDALRTR CLCDRLSTFA ILAQLSADAN MEKATLPSVT LIVGCGVSSL TLLMLVIIYV SVWRYIRSER SVILINFCLS IISSNALILI GQTQTRNKVV CTLVAAFLHF FFLSSFCWVL TEAWQSYMAV TGHLRNRLIR KRFLCLGWGL PALVVAISVG FTKAKGYSTM NYCWLSLEGG LLYAFVGPAA AVVLVNMVIG ILVFNKLVSK DGITDKKLKE RAGASLWSSC VVLPLLALTW MSAVLAVTDR RSALFQILFA VFDSLEGFVI VMVHCILRRE VQDAVKCRVV DRQEEGNGDS GGSFQNGHAQ LMTDFEKDVD LACRSVLNKD IAACRTATIT GTLKRPSLPE EEKLKLAHAK GPPTNFNSLP ANVSKLHLHG SPRYPGGPLP DFPNHSLTLK RDKAPKSSFV GDGDIFKKLD SELSRAQEKA LDTSYVILPT ATATLRPKPK EEPKYSIHID QMPQTRLIHL STAPEASLPA RSPPSRQPPS GGPPEAPPAQ PPPPPPPPPP PPQQPLPPPP NLEPAPPSLG DPGEPAAHPG PSTGPSTKNE NVATLSVSSL ERRKSRYAEL DFEKIMHTRK RHQDMFQDLN RKLQHAAEKD KEVLGPDSKP EKQQTPNKRP WESLRKAHGT PTWVKKELEP LQPSPLELRS VEWERSGATI PLVGQDIIDL QTEV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.