Details for: XPO5

Gene ID: 57510

Symbol: XPO5

Ensembl ID: ENSG00000124571

Description: exportin 5

Associated with

Other Information

Genular Protein ID: 1676126847

Symbol: XPO5_HUMAN

Name: Exportin-5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12426392

Title: Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.

PubMed ID: 12426392

DOI: 10.1093/emboj/cdf613

PubMed ID: 11777942

Title: Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.

PubMed ID: 11777942

DOI: 10.1083/jcb.200110082

PubMed ID: 10574462

Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10574462

DOI: 10.1093/dnares/6.5.337

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12426393

Title: Exportin-5-mediated nuclear export of eukaryotic elongation factor 1A and tRNA.

PubMed ID: 12426393

DOI: 10.1093/emboj/cdf620

PubMed ID: 14681208

Title: Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs.

PubMed ID: 14681208

DOI: 10.1101/gad.1158803

PubMed ID: 12509441

Title: Exportin-5 mediates nuclear export of minihelix-containing RNAs.

PubMed ID: 12509441

DOI: 10.1074/jbc.c200668200

PubMed ID: 14570900

Title: Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3.

PubMed ID: 14570900

DOI: 10.1074/jbc.m306808200

PubMed ID: 15254228

Title: Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5.

PubMed ID: 15254228

DOI: 10.1128/mcb.24.15.6608-6619.2004

PubMed ID: 14730017

Title: Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs.

PubMed ID: 14730017

DOI: 10.1261/rna.5167604

PubMed ID: 14631048

Title: Nuclear export of microRNA precursors.

PubMed ID: 14631048

DOI: 10.1126/science.1090599

PubMed ID: 15613540

Title: Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.

PubMed ID: 15613540

DOI: 10.1261/rna.7233305

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19124606

Title: RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1.

PubMed ID: 19124606

DOI: 10.1128/mcb.01519-08

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 19965479

Title: A high-resolution structure of the pre-microRNA nuclear export machinery.

PubMed ID: 19965479

DOI: 10.1126/science.1178705

PubMed ID: 26878725

Title: Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome.

PubMed ID: 26878725

DOI: 10.1038/ng.3512

Sequence Information:

  • Length: 1204
  • Mass: 136311
  • Checksum: 3295A17DF7C37602
  • Sequence:
  • MAMDQVNALC EQLVKAVTVM MDPNSTQRYR LEALKFCEEF KEKCPICVPC GLRLAEKTQV 
    AIVRHFGLQI LEHVVKFRWN GMSRLEKVYL KNSVMELIAN GTLNILEEEN HIKDALSRIV 
    VEMIKREWPQ HWPDMLIELD TLSKQGETQT ELVMFILLRL AEDVVTFQTL PPQRRRDIQQ 
    TLTQNMERIF SFLLNTLQEN VNKYQQVKTD TSQESKAQAN CRVGVAALNT LAGYIDWVSM 
    SHITAENCKL LEILCLLLNE QELQLGAAEC LLIAVSRKGK LEDRKPLMVL FGDVAMHYIL 
    SAAQTADGGG LVEKHYVFLK RLCQVLCALG NQLCALLGAD SDVETPSNFG KYLESFLAFT 
    THPSQFLRSS TQMTWGALFR HEILSRDPLL LAIIPKYLRA SMTNLVKMGF PSKTDSPSCE 
    YSRFDFDSDE DFNAFFNSSR AQQGEVMRLA CRLDPKTSFQ MAGEWLKYQL STFLDAGSVN 
    SCSAVGTGEG SLCSVFSPSF VQWEAMTLFL ESVITQMFRT LNREEIPVND GIELLQMVLN 
    FDTKDPLILS CVLTNVSALF PFVTYRPEFL PQVFSKLFSS VTFETVEESK APRTRAVRNV 
    RRHACSSIIK MCRDYPQLVL PNFDMLYNHV KQLLSNELLL TQMEKCALME ALVLISNQFK 
    NYERQKVFLE ELMAPVASIW LSQDMHRVLS DVDAFIAYVG TDQKSCDPGL EDPCGLNRAR 
    MSFCVYSILG VVKRTCWPTD LEEAKAGGFV VGYTSSGNPI FRNPCTEQIL KLLDNLLALI 
    RTHNTLYAPE MLAKMAEPFT KALDMLDAEK SAILGLPQPL LELNDSPVFK TVLERMQRFF 
    STLYENCFHI LGKAGPSMQQ DFYTVEDLAT QLLSSAFVNL NNIPDYRLRP MLRVFVKPLV 
    LFCPPEHYEA LVSPILGPLF TYLHMRLSQK WQVINQRSLL CGEDEAADEN PESQEMLEEQ 
    LVRMLTREVM DLITVCCVSK KGADHSSAPP ADGDDEEMMA TEVTPSAMAE LTDLGKCLMK 
    HEDVCTALLI TAFNSLAWKD TLSCQRTTSQ LCWPLLKQVL SGTLLADAVT WLFTSVLKGL 
    QMHGQHDGCM ASLVHLAFQI YEALRPRYLE IRAVMEQIPE IQKDSLDQFD CKLLNPSLQK 
    VADKRRKDQF KRLIAGCIGK PLGEQFRKEV HIKNLPSLFK KTKPMLETEV LDNDGGGLAT 
    IFEP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.