Details for: PCDH19

Gene ID: 57526

Symbol: PCDH19

Ensembl ID: ENSG00000165194

Description: protocadherin 19

Associated with

Other Information

Genular Protein ID: 3273508289

Symbol: PCD19_HUMAN

Name: Protocadherin-19

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 18469813

Title: X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.

PubMed ID: 18469813

DOI: 10.1038/ng.149

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 11549318

Title: Identification and characterization of three members of a novel subclass of protocadherins.

PubMed ID: 11549318

DOI: 10.1006/geno.2001.6592

PubMed ID: 20830798

Title: Novel de novo PCDH19 mutations in three unrelated females with epilepsy female restricted mental retardation syndrome.

PubMed ID: 20830798

DOI: 10.1002/ajmg.a.33611

PubMed ID: 19214208

Title: Sporadic infantile epileptic encephalopathy caused by mutations in PCDH19 resembles Dravet syndrome but mainly affects females.

PubMed ID: 19214208

DOI: 10.1371/journal.pgen.1000381

PubMed ID: 19752159

Title: Epilepsy and mental retardation limited to females with PCDH19 mutations can present de novo or in single generation families.

PubMed ID: 19752159

DOI: 10.1136/jmg.2009.068817

PubMed ID: 20713952

Title: Protocadherin 19 mutations in girls with infantile-onset epilepsy.

PubMed ID: 20713952

DOI: 10.1212/wnl.0b013e3181ed9e67

PubMed ID: 21480887

Title: Spectrum of phenotypes in female patients with epilepsy due to protocadherin 19 mutations.

PubMed ID: 21480887

DOI: 10.1111/j.1528-1167.2011.03063.x

PubMed ID: 21053371

Title: Mutations and deletions in PCDH19 account for various familial or isolated epilepsies in females.

PubMed ID: 21053371

DOI: 10.1002/humu.21373

PubMed ID: 21519002

Title: Recurrence risk of epilepsy and mental retardation in females due to parental mosaicism of PCDH19 mutations.

PubMed ID: 21519002

DOI: 10.1212/wnl.0b013e318217e7b6

PubMed ID: 22050978

Title: PCDH19 mutation in Japanese females with epilepsy.

PubMed ID: 22050978

DOI: 10.1016/j.eplepsyres.2011.10.014

PubMed ID: 22267240

Title: PCDH19-related infantile epileptic encephalopathy: An unusual X-linked inheritance disorder.

PubMed ID: 22267240

DOI: 10.1002/humu.22029

PubMed ID: 25818041

Title: Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

PubMed ID: 25818041

DOI: 10.1111/epi.12954

PubMed ID: 26993267

Title: Improving diagnosis and broadening the phenotypes in early-onset seizure and severe developmental delay disorders through gene panel analysis.

PubMed ID: 26993267

DOI: 10.1136/jmedgenet-2015-103263

PubMed ID: 27864847

Title: Diagnostic targeted resequencing in 349 patients with drug-resistant pediatric epilepsies identifies causative mutations in 30 different genes.

PubMed ID: 27864847

DOI: 10.1002/humu.23149

Sequence Information:

  • Length: 1148
  • Mass: 126253
  • Checksum: AF8721355A33C1C2
  • Sequence:
  • MESLLLPVLL LLAILWTQAA ALINLKYSVE EEQRAGTVIA NVAKDAREAG FALDPRQASA 
    FRVVSNSAPH LVDINPSSGL LVTKQKIDRD LLCRQSPKCI ISLEVMSSSM EICVIKVEIK 
    DLNDNAPSFP AAQIELEISE AASPGTRIPL DSAYDPDSGS FGVQTYELTP NELFGLEIKT 
    RGDGSRFAEL VVEKSLDRET QSHYSFRITA LDGGDPPRLG TVGLSIKVTD SNDNNPVFSE 
    STYAVSVPEN SPPNTPVIRL NASDPDEGTN GQVVYSFYGY VNDRTRELFQ IDPHSGLVTV 
    TGALDYEEGH VYELDVQAKD LGPNSIPAHC KVTVSVLDTN DNPPVINLLS VNSELVEVSE 
    SAPPGYVIAL VRVSDRDSGL NGRVQCRLLG NVPFRLQEYE SFSTILVDGR LDREQHDQYN 
    LTIQARDGGV PMLQSAKSFT VLITDENDNH PHFSKPYYQV IVQENNTPGA YLLSVSARDP 
    DLGLNGSVSY QIVPSQVRDM PVFTYVSINP NSGDIYALRS FNHEQTKAFE FKVLAKDGGL 
    PSLQSNATVR VIILDVNDNT PVITAPPLIN GTAEVYIPRN SGIGYLVTVV KAEDYDEGEN 
    GRVTYDMTEG DRGFFEIDQV NGEVRTTRTF GESSKSSYEL IVVAHDHGKT SLSASALVLI 
    YLSPALDAQE SMGSVNLSLI FIIALGSIAG ILFVTMIFVA IKCKRDNKEI RTYNCSNCLT 
    ITCLLGCFIK GQNSKCLHCI SVSPISEEQD KKTEEKVSLR GKRIAEYSYG HQKKSSKKKK 
    ISKNDIRLVP RDVEETDKMN VVSCSSLTSS LNYFDYHQQT LPLGCRRSES TFLNVENQNT 
    RNTSANHIYH HSFNSQGPQQ PDLIINGVPL PETENYSFDS NYVNSRAHLI KSSSTFKDLE 
    GNSLKDSGHE ESDQTDSEHD VQRSLYCDTA VNDVLNTSVT SMGSQMPDHD QNEGFHCREE 
    CRILGHSDRC WMPRNPMPIR SKSPEHVRNI IALSIEATAA DVEAYDDCGP TKRTFATFGK 
    DVSDHPAEER PTLKGKRTVD VTICSPKVNS VIREAGNGCE AISPVTSPLH LKSSLPTKPS 
    VSYTIALAPP ARDLEQYVNN VNNGPTRPSE AEPRGADSEK VMHEVSPILK EGRNKESPGV 
    KRLKDIVL

Genular Protein ID: 710277866

Symbol: B3KU71_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 602
  • Mass: 66614
  • Checksum: 6989369240381CDC
  • Sequence:
  • MPVFTYVSIN PNSGDIYALR SFNHEQTKAF EFKVLAKDGG LPSLQSNATV RVIILDVNDN 
    TPVITAPPLI NGTAEVYIPR NSGIGYLVTV VKAEDYDEGE NGRVTYDMTE GDRGFFEIDQ 
    VNGEVRTTRT FGESSKSSYE LIVVAHDHGK TSLSASALVL IYLSPALDAQ ESMGSVNLSL 
    IFIIALGSIA GILFVTMIFV AIKCKRDNKE IRTYNCRIAE YSYGHQKKSS KKKKISKNDI 
    RLVPRDVEET DKMNVVSCSS LTSSLNYFDY HQQTLPLGCR RSESTFLNVE NQNTRNTSAN 
    HIYHHSFNSQ GPQQPDLIIN GVPLPETENY SFDSNYVNSR AHLIKSSSTF KDLEGNSLKD 
    SGHEESDQTD SEHDVQRSLY CDTAVNDVLN TSVTSMGSQM PDHDQNEGFH CREECRILGH 
    SDRCWMPRNP MPIRSKSPEH VRNIIALSIE ATAADVEAYD DCGPTKRTFA TFGKDVSDHP 
    AEERPTLKGK RTVDVTICSP KVNSVIREAG NGCEAISPVT SPLHLKSSLP TKPSVSYTIA 
    LAPPARDLEQ YVNNVNNGPT RPSEAEPRGA DSEKVMHEVS PILKEGRNKE SPGVKRLKDI 
    VL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.