Details for: WDR35

Gene ID: 57539

Symbol: WDR35

Ensembl ID: ENSG00000118965

Description: WD repeat domain 35

Associated with

Other Information

Genular Protein ID: 3610248394

Symbol: WDR35_HUMAN

Name: Intraflagellar transport protein 121 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19450523

Title: SnapShot: Intraflagellar transport.

PubMed ID: 19450523

DOI: 10.1016/j.cell.2009.04.053

PubMed ID: 20193664

Title: Naofen, a novel WD40-repeat protein, mediates spontaneous and tumor necrosis factor-induced apoptosis.

PubMed ID: 20193664

DOI: 10.1016/j.bbrc.2010.02.133

PubMed ID: 20889716

Title: TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.

PubMed ID: 20889716

DOI: 10.1101/gad.1966210

PubMed ID: 27932497

Title: Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.

PubMed ID: 27932497

DOI: 10.1091/mbc.e16-11-0813

PubMed ID: 29220510

Title: Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis.

PubMed ID: 29220510

DOI: 10.1093/hmg/ddx421

PubMed ID: 21473986

Title: Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis.

PubMed ID: 21473986

DOI: 10.1016/j.ajhg.2011.03.015

PubMed ID: 20817137

Title: Exome sequencing identifies WDR35 variants involved in Sensenbrenner syndrome.

PubMed ID: 20817137

DOI: 10.1016/j.ajhg.2010.08.004

PubMed ID: 27158779

Title: The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery.

PubMed ID: 27158779

DOI: 10.1038/ng.3558

PubMed ID: 28400947

Title: Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia.

PubMed ID: 28400947

DOI: 10.1186/s13630-017-0051-y

Sequence Information:

  • Length: 1181
  • Mass: 133547
  • Checksum: 1C0FFAAD0287F129
  • Sequence:
  • MFFYLSKKIS IPNNVKLQCV SWNKEQGFIA CGGEDGLLKV LKLETQTDDA KLRGLAAPSN 
    LSMNQTLEGH SGSVQVVTWN EQYQKLTTSD ENGLIIVWML YKGSWIEEMI NNRNKSVVRS 
    MSWNADGQKI CIVYEDGAVI VGSVDGNRIW GKDLKGIQLS HVTWSADSKV LLFGMANGEI 
    HIYDNQGNFM IKMKLSCLVN VTGAISIAGI HWYHGTEGYV EPDCPCLAVC FDNGRCQIMR 
    HENDQNPVLI DTGMYVVGIQ WNHMGSVLAV AGFQKAAMQD KDVNIVQFYT PFGEHLGTLK 
    VPGKEISALS WEGGGLKIAL AVDSFIYFAN IRPNYKWGYC SNTVVYAYTR PDRPEYCVVF 
    WDTKNNEKYV KYVKGLISIT TCGDFCILAT KADENHPQEE NEMETFGATF VLVLCNSIGT 
    PLDPKYIDIV PLFVAMTKTH VIAASKEAFY TWQYRVAKKL TALEINQITR SRKEGRERIY 
    HVDDTPSGSM DGVLDYSKTI QGTRDPICAI TASDKILIVG RESGTIQRYS LPNVGLIQKY 
    SLNCRAYQLS LNCNSSRLAI IDISGVLTFF DLDARVTDST GQQVVGELLK LERRDVWDMK 
    WAKDNPDLFA MMEKTRMYVF RNLDPEEPIQ TSGYICNFED LEIKSVLLDE ILKDPEHPNK 
    DYLINFEIRS LRDSRALIEK VGIKDASQFI EDNPHPRLWR LLAEAALQKL DLYTAEQAFV 
    RCKDYQGIKF VKRLGKLLSE SMKQAEVVGY FGRFEEAERT YLEMDRRDLA IGLRLKLGDW 
    FRVLQLLKTG SGDADDSLLE QANNAIGDYF ADRQKWLNAV QYYVQGRNQE RLAECYYMLE 
    DYEGLENLAI SLPENHKLLP EIAQMFVRVG MCEQAVTAFL KCSQPKAAVD TCVHLNQWNK 
    AVELAKNHSM KEIGSLLARY ASHLLEKNKT LDAIELYRKA NYFFDAAKLM FKIADEEAKK 
    GSKPLRVKKL YVLSALLIEQ YHEQMKNAQR GKVKGKSSEA TSALAGLLEE EVLSTTDRFT 
    DNAWRGAEAY HFFILAQRQL YEGCVDTALK TALHLKDYED IIPPVEIYSL LALCACASRA 
    FGTCSKAFIK LKSLETLSSE QKQQYEDLAL EIFTKHTSKD NRKPELDSLM EGGEGKLPTC 
    VATGSPITEY QFWMCSVCKH GVLAQEISHY SFCPLCHSPV G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.