Details for: MICAL3

Gene ID: 57553

Symbol: MICAL3

Ensembl ID: ENSG00000243156

Description: microtubule associated monooxygenase, calponin and LIM domain containing 3

Associated with

Other Information

Genular Protein ID: 2625794065

Symbol: MICA3_HUMAN

Name: [F-actin]-monooxygenase MICAL3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 12110185

Title: MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.

PubMed ID: 12110185

DOI: 10.1016/s0092-8674(02)00794-8

PubMed ID: 15694364

Title: The MICAL proteins and rab1: a possible link to the cytoskeleton?

PubMed ID: 15694364

DOI: 10.1016/j.bbrc.2004.12.182

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21596566

Title: Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers.

PubMed ID: 21596566

DOI: 10.1016/j.cub.2011.04.030

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24440334

Title: Redox modification of nuclear actin by MICAL-2 regulates SRF signaling.

PubMed ID: 24440334

DOI: 10.1016/j.cell.2013.12.035

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26485645

Title: The ciliopathy protein CC2D2A associates with NINL and functions in RAB8-MICAL3-regulated vesicle trafficking.

PubMed ID: 26485645

DOI: 10.1371/journal.pgen.1005575

PubMed ID: 27528609

Title: MICAL3 flavoprotein monooxygenase forms a complex with centralspindlin and regulates cytokinesis.

PubMed ID: 27528609

DOI: 10.1074/jbc.m116.748186

PubMed ID: 27552051

Title: bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.

PubMed ID: 27552051

DOI: 10.7554/elife.18675

Sequence Information:

  • Length: 2002
  • Mass: 224295
  • Checksum: F85C97FD4D647B80
  • Sequence:
  • MEERKHETMN PAHVLFDRFV QATTCKGTLK AFQELCDHLE LKPKDYRSFY HKLKSKLNYW 
    KAKALWAKLD KRGSHKDYKK GKACTNTKCL IIGAGPCGLR TAIDLSLLGA KVVVIEKRDA 
    FSRNNVLHLW PFTIHDLRGL GAKKFYGKFC AGAIDHISIR QLQLILLKVA LILGIEIHVN 
    VEFQGLIQPP EDQENERIGW RALVHPKTHP VSEYEFEVII GGDGRRNTLE GFRRKEFRGK 
    LAIAITANFI NRNTTAEAKV EEISGVAFIF NQKFFQELRE ATGIDLENIV YYKDDTHYFV 
    MTAKKQSLLD KGVILHDYAD TELLLSRENV DQEALLSYAR EAADFSTQQQ LPSLDFAINH 
    YGQPDVAMFD FTCMYASENA ALVREQNGHQ LLVALVGDSL LEPFWPMGTG IARGFLAAMD 
    SAWMVRSWSL GTSPLEVLAE RESIYRLLPQ TTPENVSKNF SQYSIDPVTR YPNINVNFLR 
    PSQVRHLYDT GETKDIHLEM ESLVNSRTTP KLTRNESVAR SSKLLGWCQR QTDGYAGVNV 
    TDLTMSWKSG LALCAIIHRY RPDLIDFDSL DEQNVEKNNQ LAFDIAEKEL GISPIMTGKE 
    MASVGEPDKL SMVMYLTQFY EMFKDSLPSS DTLDLNAEEK AVLIASTRSP ISFLSKLGQT 
    ISRKRSPKDK KEKDLDGAGK RRKTSQSEEE EAPRGHRGER PTLVSTLTDR RMDVAVGNQN 
    KVKYMATQLL AKFEENAPAQ SIGIRRQGSM KKEFPQNLGG SDTCYFCQKR VYVMERLSAE 
    GKFFHRSCFK CEYCATTLRL SAYAYDIEDG KFYCKPHYCY RLSGYAQRKR PAVAPLSGKE 
    AKGPLQDGAT TDANGRANAV ASSTERTPGS GVNGLEEPSI AKRLRGTPER IELENYRLSL 
    RQAEALQEVP EETQAEHNLS SVLDTGAEED VASSSSESEM EEEGEEEEEE PRLPPSDLGG 
    VPWKEAVRIH ALLKGKSEEE LEASKSFGPG NEEEEEEEEE YEEEEEEDYD EEEEESSEAG 
    NQRLQQVMHA ADPLEIQADV HWTHIREREE EERMAPASES SASGAPLDEN DLEEDVDSEP 
    AEIEGEAAED GDPGDTGAEL DDDQHWSDSP SDADRELRLP CPAEGEAELE LRVSEDEEKL 
    PASPKHQERG PSQATSPIRS PQESALLFIP VHSPSTEGPQ LPPVPAATQE KSPEERLFPE 
    PLLPKEKPKA DAPSDLKAVH SPIRSQPVTL PEARTPVSPG SPQPQPPVAA STPPPSPLPI 
    CSQPQPSTEA TVPSPTQSPI RFQPAPAKTS TPLAPLPVQS QSDTKDRLGS PLAVDEALRR 
    SDLVEEFWMK SAEIRRSLGL TPVDRSKGPE PSFPTPAFRP VSLKSYSVEK SPQDEGLHLL 
    KPLSIPKRLG LPKPEGEPLS LPTPRSPSDR ELRSAQEERR ELSSSSGLGL HGSSSNMKTL 
    GSQSFNTSDS AMLTPPSSPP PPPPPGEEPA TLRRKLREAE PNASVVPPPL PATWMRPPRE 
    PAQPPREEVR KSFVESVEEI PFADDVEDTY DDKTEDSSLQ EKFFTPPSCW PRPEKPRHPP 
    LAKENGRLPA LEGTLQPQKR GLPLVSAEAK ELAEERMRAR EKSVKSQALR DAMARQLSRM 
    QQMELASGAP RPRKASSAPS QGKERRPDSP TRPTLRGSEE PTLKHEATSE EVLSPPSDSG 
    GPDGSFTSSE GSSGKSKKRS SLFSPRRNKK EKKSKGEGRP PEKPSSNLLE EAAAKPKSLW 
    KSVFSGYKKD KKKKADDKSC PSTPSSGATV DSGKHRVLPV VRAELQLRRQ LSFSEDSDLS 
    SDDVLEKSSQ KSRREPRTYT EEELNAKLTR RVQKAARRQA KQEELKRLHR AQIIQRQLQQ 
    VEERQRRLEE RGVAVEKALR GEAGMGKKDD PKLMQEWFKL VQEKNAMVRY ESELMIFARE 
    LELEDRQSRL QQELRERMAV EDHLKTEEEL SEEKQILNEM LEVVEQRDSL VALLEEQRLR 
    EREEDKDLEA AMLSKGFSLN WS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.