Details for: ADGRB2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 32.1471
Cell Significance Index: -13.0600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 30.4582
Cell Significance Index: -14.3800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 13.6791
Cell Significance Index: -13.0600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.5562
Cell Significance Index: 44.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4330
Cell Significance Index: 287.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.3173
Cell Significance Index: 42.1900 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.1357
Cell Significance Index: 15.1500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.9076
Cell Significance Index: 61.0300 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.7679
Cell Significance Index: 5.8900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.7495
Cell Significance Index: 74.1400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.6595
Cell Significance Index: 29.1700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6471
Cell Significance Index: 584.2800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.6172
Cell Significance Index: 23.3700 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.5798
Cell Significance Index: 14.0500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5209
Cell Significance Index: 186.8300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3840
Cell Significance Index: 62.4500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2728
Cell Significance Index: 51.9200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2367
Cell Significance Index: 14.2100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2179
Cell Significance Index: 4.7200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2178
Cell Significance Index: 150.6200 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.2076
Cell Significance Index: 2.2900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2034
Cell Significance Index: 5.8600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1671
Cell Significance Index: 10.2700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1565
Cell Significance Index: 10.8200 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.1278
Cell Significance Index: 1.5900 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.1062
Cell Significance Index: 1.0100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0418
Cell Significance Index: 1.4700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0304
Cell Significance Index: 1.3800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0248
Cell Significance Index: 0.6200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0085
Cell Significance Index: 0.1500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0030
Cell Significance Index: 0.3500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0011
Cell Significance Index: -1.7700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0018
Cell Significance Index: -1.0000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0035
Cell Significance Index: -6.4400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0039
Cell Significance Index: -7.4100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0043
Cell Significance Index: -5.8700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0130
Cell Significance Index: -0.6600 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0133
Cell Significance Index: -0.5800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0171
Cell Significance Index: -7.5400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0191
Cell Significance Index: -14.4300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0197
Cell Significance Index: -14.4100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0205
Cell Significance Index: -15.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0212
Cell Significance Index: -13.4400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0243
Cell Significance Index: -11.0100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0266
Cell Significance Index: -15.0200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.0314
Cell Significance Index: -0.4400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0319
Cell Significance Index: -0.6800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0404
Cell Significance Index: -1.6600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0408
Cell Significance Index: -11.7500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0442
Cell Significance Index: -7.9700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0482
Cell Significance Index: -9.5600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0505
Cell Significance Index: -1.2100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0508
Cell Significance Index: -7.3800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0549
Cell Significance Index: -1.7500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0573
Cell Significance Index: -0.8200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0595
Cell Significance Index: -8.1700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0605
Cell Significance Index: -3.8100 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0661
Cell Significance Index: -0.7200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0693
Cell Significance Index: -14.5900 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.0756
Cell Significance Index: -0.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0780
Cell Significance Index: -9.5900 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: -0.0895
Cell Significance Index: -0.7400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0960
Cell Significance Index: -16.3900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1029
Cell Significance Index: -3.3700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1048
Cell Significance Index: -13.4400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1074
Cell Significance Index: -13.8800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1078
Cell Significance Index: -8.2700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1130
Cell Significance Index: -11.5400 - Cell Name: glioblast (CL0000030)
Fold Change: -0.1131
Cell Significance Index: -0.7100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1211
Cell Significance Index: -14.2800 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.1214
Cell Significance Index: -2.0000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1249
Cell Significance Index: -14.3100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1301
Cell Significance Index: -7.3000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1304
Cell Significance Index: -13.5800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1335
Cell Significance Index: -7.0100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1457
Cell Significance Index: -2.8800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1531
Cell Significance Index: -3.2500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1634
Cell Significance Index: -12.1800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1685
Cell Significance Index: -2.8200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1785
Cell Significance Index: -2.6900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1824
Cell Significance Index: -14.4500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1881
Cell Significance Index: -11.5300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1972
Cell Significance Index: -13.9500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2066
Cell Significance Index: -5.7800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2201
Cell Significance Index: -7.7100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2364
Cell Significance Index: -15.2500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2393
Cell Significance Index: -5.1700 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.2403
Cell Significance Index: -3.3600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2426
Cell Significance Index: -12.6000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2432
Cell Significance Index: -6.2500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2484
Cell Significance Index: -12.9400 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.2516
Cell Significance Index: -4.3500 - Cell Name: neuron (CL0000540)
Fold Change: -0.2648
Cell Significance Index: -2.5100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2785
Cell Significance Index: -13.0900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2798
Cell Significance Index: -6.9800 - Cell Name: neural cell (CL0002319)
Fold Change: -0.3124
Cell Significance Index: -3.6500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3163
Cell Significance Index: -6.3500 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3354
Cell Significance Index: -8.8200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3417
Cell Significance Index: -15.9300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.3581
Cell Significance Index: -8.9300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2009775877
Symbol: AGRB2_HUMAN
Name: Brain-specific angiogenesis inhibitor 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9533023
Title: Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1).
PubMed ID: 9533023
DOI: 10.1159/000134693
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 20367554
Title: Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing.
PubMed ID: 20367554
PubMed ID: 21787750
Title: Identification of brain-specific angiogenesis inhibitor 2 as an interaction partner of glutaminase interacting protein.
PubMed ID: 21787750
PubMed ID: 25326458
Title: Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.
PubMed ID: 25326458
PubMed ID: 25713288
Title: International union of basic and clinical pharmacology. XCIV. Adhesion G protein-coupled receptors.
PubMed ID: 25713288
PubMed ID: 28891236
Title: A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity.
PubMed ID: 28891236
DOI: 10.1002/humu.23336
Sequence Information:
- Length: 1585
- Mass: 172656
- Checksum: 56D253AE0AB1552D
- Sequence:
MENTGWMGKG HRMTPACPLL LSVILSLRLA TAFDPAPSAC SALASGVLYG AFSLQDLFPT IASGCSWTLE NPDPTKYSLY LRFNRQEQVC AHFAPRLLPL DHYLVNFTCL RPSPEEAVAQ AESEVGRPEE EEAEAAAGLE LCSGSGPFTF LHFDKNFVQL CLSAEPSEAP RLLAPAALAF RFVEVLLINN NNSSQFTCGV LCRWSEECGR AAGRACGFAQ PGCSCPGEAG AGSTTTTSPG PPAAHTLSNA LVPGGPAPPA EADLHSGSSN DLFTTEMRYG EEPEEEPKVK TQWPRSADEP GLYMAQTGDP AAEEWSPWSV CSLTCGQGLQ VRTRSCVSSP YGTLCSGPLR ETRPCNNSAT CPVHGVWEEW GSWSLCSRSC GRGSRSRMRT CVPPQHGGKA CEGPELQTKL CSMAACPVEG QWLEWGPWGP CSTSCANGTQ QRSRKCSVAG PAWATCTGAL TDTRECSNLE CPATDSKWGP WNAWSLCSKT CDTGWQRRFR MCQATGTQGY PCEGTGEEVK PCSEKRCPAF HEMCRDEYVM LMTWKKAAAG EIIYNKCPPN ASGSASRRCL LSAQGVAYWG LPSFARCISH EYRYLYLSLR EHLAKGQRML AGEGMSQVVR SLQELLARRT YYSGDLLFSV DILRNVTDTF KRATYVPSAD DVQRFFQVVS FMVDAENKEK WDDAQQVSPG SVHLLRVVED FIHLVGDALK AFQSSLIVTD NLVISIQREP VSAVSSDITF PMRGRRGMKD WVRHSEDRLF LPKEVLSLSS PGKPATSGAA GSPGRGRGPG TVPPGPGHSH QRLLPADPDE SSYFVIGAVL YRTLGLILPP PRPPLAVTSR VMTVTVRPPT QPPAEPLITV ELSYIINGTT DPHCASWDYS RADASSGDWD TENCQTLETQ AAHTRCQCQH LSTFAVLAQP PKDLTLELAG SPSVPLVIGC AVSCMALLTL LAIYAAFWRF IKSERSIILL NFCLSILASN ILILVGQSRV LSKGVCTMTA AFLHFFFLSS FCWVLTEAWQ SYLAVIGRMR TRLVRKRFLC LGWGLPALVV AVSVGFTRTK GYGTSSYCWL SLEGGLLYAF VGPAAVIVLV NMLIGIIVFN KLMARDGISD KSKKQRAGSE RCPWASLLLP CSACGAVPSP LLSSASARNA MASLWSSCVV LPLLALTWMS AVLAMTDRRS VLFQALFAVF NSAQGFVITA VHCFLRREVQ DVVKCQMGVC RADESEDSPD SCKNGQLQIL SDFEKDVDLA CQTVLFKEVN TCNPSTITGT LSRLSLDEDE EPKSCLVGPE GSLSFSPLPG NILVPMAASP GLGEPPPPQE ANPVYMCGEG GLRQLDLTWL RPTEPGSEGD YMVLPRRTLS LQPGGGGGGG EDAPRARPEG TPRRAAKTVA HTEGYPSFLS VDHSGLGLGP AYGSLQNPYG MTFQPPPPTP SARQVPEPGE RSRTMPRTVP GSTMKMGSLE RKKLRYSDLD FEKVMHTRKR HSELYHELNQ KFHTFDRYRS QSTAKREKRW SVSSGGAAER SVCTDKPSPG ERPSLSQHRR HQSWSTFKSM TLGSLPPKPR ERLTLHRAAA WEPTEPPDGD FQTEV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.