Details for: SH3RF1

Gene ID: 57630

Symbol: SH3RF1

Ensembl ID: ENSG00000154447

Description: SH3 domain containing ring finger 1

Associated with

Other Information

Genular Protein ID: 628621594

Symbol: SH3R1_HUMAN

Name: E3 ubiquitin-protein ligase SH3RF1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10819331

Title: Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10819331

DOI: 10.1093/dnares/7.2.143

PubMed ID: 12514131

Title: POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

PubMed ID: 12514131

DOI: 10.1093/emboj/cdg021

PubMed ID: 14504284

Title: Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.

PubMed ID: 14504284

DOI: 10.1074/jbc.m307357200

PubMed ID: 15659549

Title: The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production.

PubMed ID: 15659549

DOI: 10.1073/pnas.0408717102

PubMed ID: 16230351

Title: Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

PubMed ID: 16230351

DOI: 10.1074/jbc.m509060200

PubMed ID: 16571722

Title: Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.

PubMed ID: 16571722

DOI: 10.1074/jbc.m601056200

PubMed ID: 17535800

Title: Regulation of the pro-apoptotic scaffolding protein POSH by Akt.

PubMed ID: 17535800

DOI: 10.1074/jbc.m704321200

PubMed ID: 17420289

Title: The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp.

PubMed ID: 17420289

DOI: 10.1083/jcb.200611036

PubMed ID: 19710010

Title: POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.

PubMed ID: 19710010

DOI: 10.1074/jbc.m109.041582

PubMed ID: 20696164

Title: POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain.

PubMed ID: 20696164

DOI: 10.1016/j.febslet.2010.07.060

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 888
  • Mass: 93129
  • Checksum: B3018000F03D0CF1
  • Sequence:
  • MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 
    EELPSNILLV RLLDGIKQRP WKPGPGGGSG TNCTNALRSQ SSTVANCSSK DLQSSQGGQQ 
    PRVQSWSPPV RGIPQLPCAK ALYNYEGKEP GDLKFSKGDI IILRRQVDEN WYHGEVNGIH 
    GFFPTNFVQI IKPLPQPPPQ CKALYDFEVK DKEADKDCLP FAKDDVLTVI RRVDENWAEG 
    MLADKIGIFP ISYVEFNSAA KQLIEWDKPP VPGVDAGECS SAAAQSSTAP KHSDTKKNTK 
    KRHSFTSLTM ANKSSQASQN RHSMEISPPV LISSSNPTAA ARISELSGLS CSAPSQVHIS 
    TTGLIVTPPP SSPVTTGPSF TFPSDVPYQA ALGTLNPPLP PPPLLAATVL ASTPPGATAA 
    AAAAGMGPRP MAGSTDQIAH LRPQTRPSVY VAIYPYTPRK EDELELRKGE MFLVFERCQD 
    GWFKGTSMHT SKIGVFPGNY VAPVTRAVTN ASQAKVPMST AGQTSRGVTM VSPSTAGGPA 
    QKLQGNGVAG SPSVVPAAVV SAAHIQTSPQ AKVLLHMTGQ MTVNQARNAV RTVAAHNQER 
    PTAAVTPIQV QNAAGLSPAS VGLSHHSLAS PQPAPLMPGS ATHTAAISIS RASAPLACAA 
    AAPLTSPSIT SASLEAEPSG RIVTVLPGLP TSPDSASSAC GNSSATKPDK DSKKEKKGLL 
    KLLSGASTKR KPRVSPPASP TLEVELGSAE LPLQGAVGPE LPPGGGHGRA GSCPVDGDGP 
    VTTAVAGAAL AQDAFHRKAS SLDSAVPIAP PPRQACSSLG PVLNESRPVV CERHRVVVSY 
    PPQSEAELEL KEGDIVFVHK KREDGWFKGT LQRNGKTGLF PGSFVENI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.