LSM2 | ENSG00000204392 | NCBI 57819

Details for: LSM2

Gene ID: 57819

Symbol: LSM2

Ensembl ID: ENSG00000204392

Description: LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated

Associated with

Deadenylation-dependent mrna decay
(R-HSA-429914)
Metabolism of rna
(R-HSA-8953854)
Mrna decay by 5' to 3' exoribonuclease
(R-HSA-430039)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Catalytic step 2 spliceosome
(GO:0071013)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Lsm1-7-pat1 complex
(GO:1990726)
Lsm2-8 complex
(GO:0120115)
Mrna catabolic process
(GO:0006402)
Mrna splicing, via spliceosome
(GO:0000398)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
P-body
(GO:0000932)
Precatalytic spliceosome
(GO:0071011)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Small gtpase binding
(GO:0031267)
Spliceosomal tri-snrnp complex assembly
(GO:0000244)
U2-type precatalytic spliceosome
(GO:0071005)
U4/u6 x u5 tri-snrnp complex
(GO:0046540)
U6 snrna binding
(GO:0017070)
U6 snrnp
(GO:0005688)

Other Information

Proteins

U6 snRNA-associated Sm-like protein LSm2

Genular Protein ID: 4212546486

Symbol: LSM2_HUMAN

Name: U6 snRNA-associated Sm-like protein LSm2

UniProtKB Accession Codes:

Q9Y333 Q6FGG1

Database IDs:

Citations:

PubMed ID: 10523320

Title: A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

PubMed ID: 10523320

DOI: 10.1093/emboj/18.20.5789

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 26912367

Title: Molecular architecture of the human U4/U6.U5 tri-snRNP.

PubMed ID: 26912367

DOI: 10.1126/science.aad2085

PubMed ID: 28781166

Title: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

PubMed ID: 28781166

DOI: 10.1016/j.cell.2017.07.011

Sequence Information:

Length: 95
Mass: 10835
Checksum: 623591A09A6ABACE
Sequence:

MLFYSFFKSL VGKDVVVELK NDLSICGTLH SVDQYLNIKL TDISVTDPEK YPHMLSVKNC 
FIRGSVVRYV QLPADEVDTQ LLQDAARKEA LQQKQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: LSM2

Associated with

Other Information

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. PubMed ID: 10523320

Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. PubMed ID: 14656967

Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. PubMed ID: 10931946

The DNA sequence and analysis of human chromosome 6. PubMed ID: 14574404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. PubMed ID: 11991638

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

Initial characterization of the human central proteome. PubMed ID: 21269460

Molecular architecture of the human U4/U6.U5 tri-snRNP. PubMed ID: 26912367

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. PubMed ID: 28781166