CYP4F11 | ENSG00000171903 | NCBI 57834

Details for: CYP4F11

Gene ID: 57834

Symbol: CYP4F11

Ensembl ID: ENSG00000171903

Description: cytochrome P450 family 4 subfamily F member 11

Associated with

Arachidonic acid metabolism
(R-HSA-2142753)
Biological oxidations
(R-HSA-211859)
Cytochrome p450 - arranged by substrate type
(R-HSA-211897)
Eicosanoids
(R-HSA-211979)
Fatty acid metabolism
(R-HSA-8978868)
Fatty acids
(R-HSA-211935)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Miscellaneous substrates
(R-HSA-211958)
Phase i - functionalization of compounds
(R-HSA-211945)
Synthesis of leukotrienes (lt) and eoxins (ex)
(R-HSA-2142691)
Arachidonic acid metabolic process
(GO:0019369)
Aromatase activity
(GO:0070330)
Blood coagulation
(GO:0007596)
Cytochrome metabolic process
(GO:1903604)
Endoplasmic reticulum membrane
(GO:0005789)
Fatty acid binding
(GO:0005504)
Fatty acid metabolic process
(GO:0006631)
Heme binding
(GO:0020037)
Iron ion binding
(GO:0005506)
Long-chain fatty acid omega-hydroxylase activity
(GO:0102033)
Menaquinone catabolic process
(GO:0042361)
Monooxygenase activity
(GO:0004497)
Omega-hydroxylase p450 pathway
(GO:0097267)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, nad(p)h as one donor, and incorporation of one atom of oxygen
(GO:0016709)
Oxylipin biosynthetic process
(GO:0031408)
Phylloquinone catabolic process
(GO:0042376)
Protein binding
(GO:0005515)
Vitamin k catabolic process
(GO:0042377)

Other Information

Proteins

CP4FB_HUMAN

Genular Protein ID: 4281810767

Symbol: CP4FB_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9HBI6 A0A024R7G0 A8K059 O75254 Q96AQ5

Database IDs:

Citations:

PubMed ID: 10964514

Title: A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization.

PubMed ID: 10964514

DOI: 10.1006/geno.2000.6276

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15364545

Title: Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

PubMed ID: 15364545

DOI: 10.1016/j.taap.2003.12.033

PubMed ID: 18065749

Title: Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

PubMed ID: 18065749

DOI: 10.1194/jlr.m700450-jlr200

PubMed ID: 19932081

Title: Human cytochrome P450 4F11: heterologous expression in bacteria, purification, and characterization of catalytic function.

PubMed ID: 19932081

DOI: 10.1016/j.abb.2009.11.017

PubMed ID: 24138531

Title: Cytochrome P450-dependent catabolism of vitamin K: omega-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

PubMed ID: 24138531

DOI: 10.1021/bi401208m

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 36565673

Title: Deciphering the biotransformation mechanism of dialkylresorcinols by CYP4F11.

PubMed ID: 36565673

DOI: 10.1016/j.bioorg.2022.106330

Sequence Information:

Length: 524
Mass: 60146
Checksum: 8B0F14C52E657CB2
Sequence:

MPQLSLSWLG LGPVAASPWL LLLLVGGSWL LARVLAWTYT FYDNCRRLQC FPQPPKQNWF 
WGHQGLVTPT EEGMKTLTQL VTTYPQGFKL WLGPTFPLLI LCHPDIIRPI TSASAAVAPK 
DMIFYGFLKP WLGDGLLLSG GDKWSRHRRM LTPAFHFNIL KPYMKIFNKS VNIMHDKWQR 
LASEGSARLD MFEHISLMTL DSLQKCVFSF ESNCQEKPSE YIAAILELSA FVEKRNQQIL 
LHTDFLYYLT PDGQRFRRAC HLVHDFTDAV IQERRCTLPT QGIDDFLKNK AKSKTLDFID 
VLLLSKDEDG KELSDEDIRA EADTFMFEGH DTTASGLSWV LYHLAKHPEY QEQCRQEVQE 
LLKDREPIEI EWDDLAQLPF LTMCIKESLR LHPPVPVISR CCTQDFVLPD GRVIPKGIVC 
LINIIGIHYN PTVWPDPEVY DPFRFDQENI KERSPLAFIP FSAGPRNCIG QAFAMAEMKV 
VLALTLLHFR ILPTHTEPRR KPELILRAEG GLWLRVEPLG ANSQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CYP4F11

Associated with

Other Information

A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization. PubMed ID: 10964514

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. PubMed ID: 15364545

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11. PubMed ID: 18065749

Human cytochrome P450 4F11: heterologous expression in bacteria, purification, and characterization of catalytic function. PubMed ID: 19932081

Cytochrome P450-dependent catabolism of vitamin K: omega-hydroxylation catalyzed by human CYP4F2 and CYP4F11. PubMed ID: 24138531

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Deciphering the biotransformation mechanism of dialkylresorcinols by CYP4F11. PubMed ID: 36565673