NKX3 2 | ENSG00000109705 | NCBI 579

Details for: NKX3 2

Gene ID: 579

Symbol: NKX3 2

Ensembl ID: ENSG00000109705

Description: NK3 homeobox 2

Associated with

Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Regulation of runx2 expression and activity
(R-HSA-8939902)
Rna polymerase ii transcription
(R-HSA-73857)
Transcriptional regulation by runx2
(R-HSA-8878166)
Animal organ formation
(GO:0048645)
Cell differentiation
(GO:0030154)
Chromatin
(GO:0000785)
Determination of left/right symmetry
(GO:0007368)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Embryonic skeletal system development
(GO:0048706)
Intestinal epithelial cell development
(GO:0060576)
Middle ear morphogenesis
(GO:0042474)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of chondrocyte differentiation
(GO:0032331)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Pancreas development
(GO:0031016)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Skeletal system development
(GO:0001501)
Skeletal system morphogenesis
(GO:0048705)
Spleen development
(GO:0048536)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

Homeobox protein Nkx-3.2

Genular Protein ID: 2102903824

Symbol: NKX32_HUMAN

Name: Homeobox protein Nkx-3.2

UniProtKB Accession Codes:

P78367 Q2M2I7

Database IDs:

Citations:

PubMed ID: 9426254

Title: Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe.

PubMed ID: 9426254

DOI: 10.1016/s0378-1119(97)00520-9

PubMed ID: 9344671

Title: Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.

PubMed ID: 9344671

DOI: 10.1006/geno.1997.4926

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9256352

Title: Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton.

PubMed ID: 9256352

DOI: 10.1016/s0925-4773(97)00067-1

PubMed ID: 20004766

Title: Homozygous inactivating mutations in the NKX3-2 gene result in spondylo-megaepiphyseal-metaphyseal dysplasia.

PubMed ID: 20004766

DOI: 10.1016/j.ajhg.2009.11.005

Sequence Information:

Length: 333
Mass: 34814
Checksum: 8C406E188D27780B
Sequence:

MAVRGANTLT SFSIQAILNK KEERGGLAAP EGRPAPGGTA ASVAAAPAVC CWRLFGERDA 
GALGGAEDSL LASPAGTRTA AGRTAESPEG WDSDSALSEE NESRRRCADA RGASGAGLAG 
GSLSLGQPVC ELAASKDLEE EAAGRSDSEM SASVSGDRSP RTEDDGVGPR GAHVSALCSG 
AGGGGGSGPA GVAEEEEEPA APKPRKKRSR AAFSHAQVFE LERRFNHQRY LSGPERADLA 
ASLKLTETQV KIWFQNRRYK TKRRQMAADL LASAPAAKKV AVKVLVRDDQ RQYLPGEVLR 
PPSLLPLQPS YYYPYYCLPG WALSTCAAAA GTQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NKX3 2

Associated with

Other Information

Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe. PubMed ID: 9426254

Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia. PubMed ID: 9344671

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334