Details for: Gsdma

Gene ID: 57911

Symbol: Gsdma

Ensembl ID: ENSMUSG00000017204

Description: gasdermin A

Associated with

Other Information

Genular Protein ID: 2538035021

Symbol: GSDMA_MOUSE

Name: Gasdermin-A

UniProtKB Accession Codes:

Q9EST1 A3KFN3

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 1 GO 11 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10967128

Title: Gasdermin (Gsdm) localizing to mouse chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells.

PubMed ID: 10967128

DOI: 10.1007/s003350010138

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 17350798

Title: Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner.

PubMed ID: 17350798

DOI: 10.1016/j.ygeno.2007.01.003

PubMed ID: 35110732

Title: Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis.

PubMed ID: 35110732

DOI: 10.1038/s41586-021-04384-4

PubMed ID: 35545676

Title: Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes.

PubMed ID: 35545676

DOI: 10.1038/s41586-022-04717-x

Sequence Information:

  • Length: 446
  • Mass: 49593
  • Checksum: 603673EC007CB305
  • Sequence:
    • MTMFENVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG ARYVHTDYTL 
LDVLEPGSSP SDPTDSGNFS FKNMLDARVE GDVDVPKTVK VKGTAGLSRS STLEVQTLSV 
APTALENLHK ERKLSADHPF LKEMRERGEN LYVVMEVVET LQEVTLERAG KAEGCFSLPF 
FAPLGLQGSV NHKEAVTIPK GCVLAYRVRQ LMVNGKDEWG IPHICNDSMQ TFPPGEKPGE 
GKFILIQASD VGEMHEDFKT LKEEVQRETQ EVEKLSPVGR SSLLTSLSHL LGKKKELQDL 
EQTLEGALDK GHEVTLEALP KDVLLSKDAM DAILYFLGAL TVLSEAQQKL LVKSLEKKIL 
PVQLKLVEST MEKNFLQDKE GVFPLQPDLL SSLGEEELIL TEALVGLSGL EVQRSGPQYT 
WDPDTLPHLC ALYAGLSLLQ LLSKNS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.