pycard | ENSDARG00000040076 | NCBI 57923

Details for: pycard

Gene ID: 57923

Symbol: pycard

Ensembl ID: ENSDARG00000040076

Description: PYD and CARD domain containing

Associated with

Apoptosis
(R-DRE-109581)
Apoptotic factor-mediated response
(R-DRE-111471)
Cytochrome c-mediated apoptotic response
(R-DRE-111461)
Formation of apoptosome
(R-DRE-111458)
Immune system
(R-DRE-168256)
Inflammasomes
(R-DRE-622312)
Innate immune system
(R-DRE-168249)
Intrinsic pathway for apoptosis
(R-DRE-109606)
Neutrophil degranulation
(R-DRE-6798695)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-DRE-168643)
Programmed cell death
(R-DRE-5357801)
Regulation of the apoptosome activity
(R-DRE-9627069)
The nlrp1 inflammasome
(R-DRE-844455)
The nlrp3 inflammasome
(R-DRE-844456)
Apoptotic process
(GO:0006915)
Canonical inflammasome complex
(GO:0061702)
Cytoplasm
(GO:0005737)
Defense response to bacterium
(GO:0042742)
Immune system process
(GO:0002376)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Nlrp3 inflammasome complex
(GO:0072559)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)
Protein binding
(GO:0005515)
Pyrin domain binding
(GO:0032090)
Regulation of apoptotic process
(GO:0042981)
Regulation of inflammatory response
(GO:0050727)

Other Information

Proteins

Q4VBV3_DANRE

Genular Protein ID: 2173481906

Symbol: Q4VBV3_DANRE

Name: N/A

UniProtKB Accession Codes:

Q4VBV3

Database IDs:

Citations:

PubMed ID: 11250163

Title: The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation.

PubMed ID: 11250163

DOI: 10.1016/S0960-9822(01)00056-2

PubMed ID: 12464617

Title: Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development.

PubMed ID: 12464617

DOI: 10.1074/jbc.M203944200

PubMed ID: 17850868

Title: Molecular cloning and expression analysis of the ASC gene from mandarin fish and its regulation of NF-kappaB activation.

PubMed ID: 17850868

DOI: 10.1016/j.dci.2007.07.006

PubMed ID: 19699229

Title: Structure and expression pattern of teleost caspase recruitment domain (CARD) containing proteins that are potentially involved in NF-kappaB signalling.

PubMed ID: 19699229

DOI: 10.1016/j.dci.2009.08.002

PubMed ID: 22988238

Title: Activation of NF-kappaB protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish.

PubMed ID: 22988238

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 29791979

Title: Functional and structural characterization of zebrafish ASC.

PubMed ID: 29791979

DOI: 10.1111/febs.14514

PubMed ID: 30150286

Title: Characterization of an NLRP1 Inflammasome from Zebrafish Reveals a Unique Sequential Activation Mechanism Underlying Inflammatory Caspases in Ancient Vertebrates.

PubMed ID: 30150286

DOI: 10.4049/jimmunol.1800498

PubMed ID: 30693866

Title: Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection.

PubMed ID: 30693866

PubMed ID: 31174991

Title: Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1.

PubMed ID: 31174991

PubMed ID: 31160464

Title: Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner.

PubMed ID: 31160464

Sequence Information:

Length: 203
Mass: 22849
Checksum: 47D02BBC4DA20516
Sequence:

MAESFKEHLQ EAFEDLGADN LRKFKSKLGD RRQEPRVTKS AIEKLKDEID LADLMVGVFT 
SKDAVSVTVE ILRAIKCIAV ADDLLRNTGQ SESKGAPSDE SKCASSKAVS KVAFSKVNFI 
DEHWKELIDR VNNVDPILDI LRQKKVITNE DYCTIRNKET PQKKMRELLT GPITCAGNKG 
KEVLYDALRE SNKFLMDDLE DAQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: pycard

Associated with

Other Information

The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation. PubMed ID: 11250163

Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development. PubMed ID: 12464617

Molecular cloning and expression analysis of the ASC gene from mandarin fish and its regulation of NF-kappaB activation. PubMed ID: 17850868

Structure and expression pattern of teleost caspase recruitment domain (CARD) containing proteins that are potentially involved in NF-kappaB signalling. PubMed ID: 19699229

Activation of NF-kappaB protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish. PubMed ID: 22988238

The zebrafish reference genome sequence and its relationship to the human genome. PubMed ID: 23594743

Functional and structural characterization of zebrafish ASC. PubMed ID: 29791979

Characterization of an NLRP1 Inflammasome from Zebrafish Reveals a Unique Sequential Activation Mechanism Underlying Inflammatory Caspases in Ancient Vertebrates. PubMed ID: 30150286

Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection. PubMed ID: 30693866

Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. PubMed ID: 31174991

Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner. PubMed ID: 31160464